4-aminopyridine has been researched along with Acute Disease in 13 studies
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Hence, thalidomide (100, 200 and 400 mg/kg) was herein administered to mice to evaluate possible protection against seizures induced by the systemic administration of neurotoxins: 10 mg/kg of 4-aminopyridine (4-AP), 90 mg/kg of pentylenetetrazol (PTZ), or 380 mg/kg of pilocarpine." | 7.88 | Thalidomide protects against acute pentylenetetrazol and pilocarpine-induced seizures in mice. ( Campos-Rodriguez, C; Islas-Espinoza, AM; San Juan, ER, 2018) |
| " Hence, thalidomide (100, 200 and 400 mg/kg) was herein administered to mice to evaluate possible protection against seizures induced by the systemic administration of neurotoxins: 10 mg/kg of 4-aminopyridine (4-AP), 90 mg/kg of pentylenetetrazol (PTZ), or 380 mg/kg of pilocarpine." | 3.88 | Thalidomide protects against acute pentylenetetrazol and pilocarpine-induced seizures in mice. ( Campos-Rodriguez, C; Islas-Espinoza, AM; San Juan, ER, 2018) |
| " We tested the effects of inhibitors of calcium-dependent K(+) channels [iberiotoxin (50 nM) and tetraethylammonium (TEA, 1 mM)] on changes in arteriolar diameter during acute hypertension." | 3.70 | Potassium channels modulate cerebral autoregulation during acute hypertension. ( Faraci, FM; Heistad, DD; Paternò, R, 2000) |
| "We describe a patient with respiratory failure secondary to LEMS who responded to 3,4-diaminopyridine and review the 12 previously reported cases of ventilatory failure in LEMS." | 2.39 | Acute ventilatory failure in Lambert-Eaton myasthenic syndrome and its response to 3,4-diaminopyridine. ( Smith, AG; Wald, J, 1996) |
| "A closed-loop seizure control system was then implemented based on optimal eTBS parameters." | 1.40 | Suppression of acute seizures by theta burst electrical stimulation of the hippocampal commissure using a closed-loop system. ( Chiang, CC; Ju, MS; Lin, CC; Siah, BH, 2014) |
| "Regional myocardial ischemia was produced in an isolated, arterially perfused canine right ventricular wedge preparation." | 1.32 | Phase 2 reentry as a trigger to initiate ventricular fibrillation during early acute myocardial ischemia. ( Guo, D; Hlaing, T; Joshi, A; Kowey, PR; Martin, J; Xu, X; Yan, GX, 2004) |
| " The dose-response characteristics of acutely and chronically injured axons were compared." | 1.30 | Conduction block in acute and chronic spinal cord injury: different dose-response characteristics for reversal by 4-aminopyridine. ( Blight, AR; Kelly, TM; Shi, R, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Manto, KM | 1 |
| Govindappa, PK | 1 |
| Parisi, D | 1 |
| Karuman, Z | 1 |
| Martinazzi, B | 1 |
| Hegarty, JP | 1 |
| Talukder, MAH | 1 |
| Elfar, JC | 1 |
| Islas-Espinoza, AM | 1 |
| Campos-Rodriguez, C | 1 |
| San Juan, ER | 1 |
| Guevara, E | 1 |
| Pouliot, P | 1 |
| Nguyen, DK | 1 |
| Lesage, F | 1 |
| Siah, BH | 1 |
| Chiang, CC | 1 |
| Ju, MS | 1 |
| Lin, CC | 1 |
| Yan, GX | 1 |
| Joshi, A | 1 |
| Guo, D | 1 |
| Hlaing, T | 1 |
| Martin, J | 1 |
| Xu, X | 1 |
| Kowey, PR | 1 |
| Boërio, D | 1 |
| Lefaucheur, JP | 1 |
| Hogrel, JY | 1 |
| Créange, A | 1 |
| Fiszer, M | 1 |
| Kołaciński, Z | 1 |
| Rechciński, T | 1 |
| Haghighi, SS | 1 |
| Pugh, SL | 1 |
| Perez-Espejo, MA | 1 |
| Oro, JJ | 1 |
| Smith, AG | 1 |
| Wald, J | 1 |
| Fehlings, MG | 1 |
| Nashmi, R | 1 |
| Shi, R | 1 |
| Kelly, TM | 1 |
| Blight, AR | 1 |
| Paternò, R | 1 |
| Heistad, DD | 1 |
| Faraci, FM | 1 |
| Bowe, CM | 1 |
| Veale, K | 1 |
2 reviews available for 4-aminopyridine and Acute Disease
| Article | Year |
|---|---|
[Pathophysiology and treatment of fatigue in multiple sclerosis].
Topics: 4-Aminopyridine; Acute Disease; Amantadine; Amifampridine; Asthenia; Benzhydryl Compounds; Central N | 2006 |
Acute ventilatory failure in Lambert-Eaton myasthenic syndrome and its response to 3,4-diaminopyridine.
Topics: 4-Aminopyridine; Acute Disease; Amifampridine; Female; Humans; Lambert-Eaton Myasthenic Syndrome; Mi | 1996 |
11 other studies available for 4-aminopyridine and Acute Disease
| Article | Year |
|---|---|
(4-Aminopyridine)-PLGA-PEG as a Novel Thermosensitive and Locally Injectable Treatment for Acute Peripheral Nerve Injury.
Topics: 4-Aminopyridine; Acute Disease; Animals; Biocompatible Materials; Disease Models, Animal; Male; Mate | 2021 |
Thalidomide protects against acute pentylenetetrazol and pilocarpine-induced seizures in mice.
Topics: 4-Aminopyridine; Acute Disease; Animals; Anticonvulsants; Disease Models, Animal; Drug Therapy, Comb | 2018 |
Optical imaging of acute epileptic networks in mice.
Topics: 4-Aminopyridine; Acute Disease; Animals; Cerebral Cortex; Cerebrovascular Circulation; Epilepsy; Mal | 2013 |
Suppression of acute seizures by theta burst electrical stimulation of the hippocampal commissure using a closed-loop system.
Topics: 4-Aminopyridine; Acute Disease; Animals; Disease Models, Animal; Electric Stimulation Therapy; Forni | 2014 |
Phase 2 reentry as a trigger to initiate ventricular fibrillation during early acute myocardial ischemia.
Topics: 4-Aminopyridine; Action Potentials; Acute Disease; Animals; Cardiac Complexes, Premature; Cardiac Pa | 2004 |
[The application of 4-aminopyridine in calcium channel inhibitors acute poisoning].
Topics: 4-Aminopyridine; Acute Disease; Adrenergic beta-Antagonists; Adult; Antidotes; Antihypertensive Agen | 2007 |
Effect of 4-aminopyridine in acute spinal cord injury.
Topics: 4-Aminopyridine; Acute Disease; Animals; Disease Models, Animal; Evoked Potentials, Somatosensory; N | 1995 |
A new model of acute compressive spinal cord injury in vitro.
Topics: 4-Aminopyridine; Action Potentials; Acute Disease; Animals; Axons; Disease Models, Animal; Electroph | 1997 |
Conduction block in acute and chronic spinal cord injury: different dose-response characteristics for reversal by 4-aminopyridine.
Topics: 4-Aminopyridine; Action Potentials; Acute Disease; Animals; Chronic Disease; Dose-Response Relations | 1997 |
Potassium channels modulate cerebral autoregulation during acute hypertension.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4-Aminopyridine; Acute Disease; | 2000 |
Sensitivity to 4-aminopyridine observed in mammalian sciatic nerves during acute pyridoxine-induced sensory neuropathy and recovery.
Topics: 4-Aminopyridine; Action Potentials; Acute Disease; Aminopyridines; Animals; Female; Nerve Fibers, My | 1988 |