4-aminopyridine has been researched along with Absence Status in 18 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "2 channel and of its major modulator, voltage-dependent potassium channel-interacting protein (KChIP1), is altered following lithium-pilocarpine induced status epilepticus (SE) and the chronic-epilepsy phase in the rat model." | 7.74 | Altered expression of voltage-gated potassium channel 4.2 and voltage-gated potassium channel 4-interacting protein, and changes in intracellular calcium levels following lithium-pilocarpine-induced status epilepticus. ( Cong, WD; Deng, WY; Liao, WP; Long, YS; Luo, AH; Su, T; Sun, WW, 2008) |
| "We investigated the effects of valproate (VPA) on an in vivo model of status epilepticus (SE) induced by intrahippocampal application of 4-aminopyridine (4-AP)." | 7.72 | Valproate suppresses status epilepticus induced by 4-aminopyridine in CA1 hippocampus region. ( Martín, ED; Pozo, MA, 2003) |
| " Furthermore, real-time measurement of lactate and oxygen concentration dynamics concurrently with network electrical activity during status epilepticus induced by 4-aminopyridine (4-AP) demonstrated phasic changes in lactate levels that correlated with bursts of electrical activity, while tonic levels of lactate remained stable during seizures." | 4.84 | Amperometric bio-sensing of lactate and oxygen concurrently with local field potentials during status epilepticus. ( Barbosa, RM; Fernandes, E; Gerhardt, GA; Ledo, A, 2024) |
| " In this study we used the pilocarpine-induced status epilepticus model of TLE (i." | 3.91 | Altered A-type potassium channel function in the nucleus tractus solitarii in acquired temporal lobe epilepsy. ( Derera, ID; Smith, BN; Smith, KC, 2019) |
| "2 channel and of its major modulator, voltage-dependent potassium channel-interacting protein (KChIP1), is altered following lithium-pilocarpine induced status epilepticus (SE) and the chronic-epilepsy phase in the rat model." | 3.74 | Altered expression of voltage-gated potassium channel 4.2 and voltage-gated potassium channel 4-interacting protein, and changes in intracellular calcium levels following lithium-pilocarpine-induced status epilepticus. ( Cong, WD; Deng, WY; Liao, WP; Long, YS; Luo, AH; Su, T; Sun, WW, 2008) |
| "We investigated the potential of 4-AP (50-100 microM) to induce seizure-like events (SLEs) in combined entorhinal cortex-hippocampal slices from Sprague Dawley rats which developed spontaneous limbic seizures following kainic acid induced status epilepticus." | 3.74 | Reduced ictogenic potential of 4-aminopyridine in the perirhinal and entorhinal cortex of kainate-treated chronic epileptic rats. ( Derst, C; Gruber, C; Heinemann, U; Tolner, EA; Veh, RW; Zahn, RK, 2008) |
| "We investigated the effects of valproate (VPA) on an in vivo model of status epilepticus (SE) induced by intrahippocampal application of 4-aminopyridine (4-AP)." | 3.72 | Valproate suppresses status epilepticus induced by 4-aminopyridine in CA1 hippocampus region. ( Martín, ED; Pozo, MA, 2003) |
| "Status epilepticus (SE) is defined as a seizure lasting more than 5min or a period of recurrent seizures without recovery between them." | 1.43 | High frequency oscillations can pinpoint seizures progressing to status epilepticus. ( Avoli, M; Lévesque, M; Salami, P, 2016) |
| "IL-1R1 knockout or IL-1RA enhanced the seizure refractory phenomenon without influencing the baseline seizure threshold in intermittent MES model." | 1.42 | The Pro-inflammatory Cytokine Interleukin-1β is a Key Regulatory Factor for the Postictal Suppression in Mice. ( Chen, B; Chen, Z; Hu, WW; Shi, LY; Tang, YS; Tao, AF; Wang, Y; Wu, XH; Xu, CL; Xu, ZH; Zhang, J; Zhang, SH; Zhao, HW, 2015) |
| "The behavioral signs of the developing epileptic seizures were scored in all rats." | 1.35 | Status epilepticus affects the gigantocellular network of the pontine reticular formation. ( Baracskay, P; Czurkó, A; Juhász, G; Kékesi, KA; Kiglics, V, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 6 (33.33) | 29.6817 |
| 2010's | 6 (33.33) | 24.3611 |
| 2020's | 4 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Maghbooli, M | 2 |
| Jourahmad, Z | 2 |
| Golizadeh, M | 2 |
| Fernandes, E | 1 |
| Ledo, A | 1 |
| Gerhardt, GA | 1 |
| Barbosa, RM | 1 |
| Lisgaras, CP | 1 |
| Mikroulis, A | 1 |
| Psarropoulou, C | 1 |
| Van Looy, E | 1 |
| Van Dycke, A | 1 |
| Vanopdenbosch, L | 1 |
| Panicucci, E | 1 |
| Cohen, M | 1 |
| Bourg, V | 1 |
| Rocher, F | 1 |
| Thomas, P | 1 |
| Lebrun, C | 1 |
| Farrell, R | 1 |
| Derera, ID | 1 |
| Smith, KC | 1 |
| Smith, BN | 1 |
| Tao, AF | 1 |
| Xu, ZH | 1 |
| Chen, B | 1 |
| Wang, Y | 1 |
| Wu, XH | 1 |
| Zhang, J | 1 |
| Tang, YS | 1 |
| Xu, CL | 1 |
| Zhao, HW | 1 |
| Hu, WW | 1 |
| Shi, LY | 1 |
| Zhang, SH | 1 |
| Chen, Z | 1 |
| Salami, P | 1 |
| Lévesque, M | 1 |
| Avoli, M | 1 |
| Su, T | 1 |
| Cong, WD | 1 |
| Long, YS | 1 |
| Luo, AH | 1 |
| Sun, WW | 1 |
| Deng, WY | 1 |
| Liao, WP | 1 |
| Burton, JM | 1 |
| Bell, CM | 1 |
| Walker, SE | 1 |
| O'Connor, PW | 1 |
| Baracskay, P | 1 |
| Kiglics, V | 1 |
| Kékesi, KA | 1 |
| Juhász, G | 1 |
| Czurkó, A | 1 |
| de Gusmao, CM | 1 |
| Ortega, MR | 1 |
| Wallace, DM | 1 |
| Martín, ED | 2 |
| Pozo, MA | 2 |
| Ceña, V | 1 |
| Zahn, RK | 1 |
| Tolner, EA | 1 |
| Derst, C | 1 |
| Gruber, C | 1 |
| Veh, RW | 1 |
| Heinemann, U | 1 |
| Hochman, DW | 1 |
| Baraban, SC | 1 |
| Owens, JW | 1 |
| Schwartzkroin, PA | 1 |
| Giménez-Llort, L | 1 |
| De Vera, N | 1 |
| Martínez, E | 1 |
1 review available for 4-aminopyridine and Absence Status
17 other studies available for 4-aminopyridine and Absence Status
| Article | Year |
|---|---|
Amperometric bio-sensing of lactate and oxygen concurrently with local field potentials during status epilepticus.
Topics: 4-Aminopyridine; Animals; Biosensing Techniques; Brain; Epilepsy; Humans; Lactic Acid; Oxygen; Rats; | 2024 |
Region-specific Effects of Early-life Status Epilepticus on the Adult Hippocampal CA3 - Medial Entorhinal Cortex Circuitry In vitro: Focus on Interictal Spikes and Concurrent High-frequency Oscillations.
Topics: 4-Aminopyridine; Animals; Entorhinal Cortex; Hippocampus; Pentylenetetrazole; Rats; Status Epileptic | 2021 |
Two related cases of super-refractory status epilepticus due to 4-aminopyridine intoxication and an overview of the literature.
Topics: 4-Aminopyridine; Anticonvulsants; Humans; Status Epilepticus | 2021 |
De novo convulsive status epilepticus in patients with multiple sclerosis treated with dalfampridine.
Topics: 4-Aminopyridine; Adult; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Multiple Sclerosis, R | 2019 |
Clinical commentary on "De novo convulsive status epilepticus in patients with multiple sclerosis treated with dalfampridine".
Topics: 4-Aminopyridine; Humans; Multiple Sclerosis; Potassium Channel Blockers; Status Epilepticus | 2019 |
Altered A-type potassium channel function in the nucleus tractus solitarii in acquired temporal lobe epilepsy.
Topics: 4-Aminopyridine; Action Potentials; Animals; Brugada Syndrome; Disease Models, Animal; Epilepsy, Tem | 2019 |
The Pro-inflammatory Cytokine Interleukin-1β is a Key Regulatory Factor for the Postictal Suppression in Mice.
Topics: 4-Aminopyridine; Animals; Disease Models, Animal; Electroshock; Hippocampus; Humans; Interleukin 1 R | 2015 |
High frequency oscillations can pinpoint seizures progressing to status epilepticus.
Topics: 4-Aminopyridine; Animals; Brain Waves; Disease Models, Animal; Disease Progression; Electroencephalo | 2016 |
Altered expression of voltage-gated potassium channel 4.2 and voltage-gated potassium channel 4-interacting protein, and changes in intracellular calcium levels following lithium-pilocarpine-induced status epilepticus.
Topics: 4-Aminopyridine; Animals; Calcium; Disease Models, Animal; Extracellular Fluid; Female; Gene Express | 2008 |
4-aminopyridine toxicity with unintentional overdose in four patients with multiple sclerosis.
Topics: 4-Aminopyridine; Canada; Chromatography, Liquid; Critical Care; Drug Compounding; Drug Overdose; Fem | 2008 |
Status epilepticus affects the gigantocellular network of the pontine reticular formation.
Topics: 4-Aminopyridine; Action Potentials; Animals; Cell Shape; Electrodes, Implanted; Electroencephalograp | 2009 |
Status epilepticus associated with dalfampridine in a patient with multiple sclerosis.
Topics: 4-Aminopyridine; Cocaine; Humans; Male; Middle Aged; Multiple Sclerosis; Potassium Channel Blockers; | 2012 |
Valproate suppresses status epilepticus induced by 4-aminopyridine in CA1 hippocampus region.
Topics: 4-Aminopyridine; Animals; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; E | 2003 |
Cholinergic modulation of status epilepticus in the rat barrel field region of primary somatosensory cortex.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Disease Models, Animal; Electroencephalography; Electromyog | 2005 |
Reduced ictogenic potential of 4-aminopyridine in the perirhinal and entorhinal cortex of kainate-treated chronic epileptic rats.
Topics: 4-Aminopyridine; Animals; Cell Count; Disease Models, Animal; Dose-Response Relationship, Drug; Elec | 2008 |
Dissociation of synchronization and excitability in furosemide blockade of epileptiform activity.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Bicuculline; Electric Stimulation; Entorhinal Cortex; Ext | 1995 |
Analysis of chemically-induced alterations of the motor activity in rats.
Topics: 4-Aminopyridine; Animals; Convulsants; Epilepsy, Tonic-Clonic; Kainic Acid; Male; Motor Activity; Pe | 1998 |