4-aminopyrazolo(3,4-d)pyrimidine has been researched along with Chagas Disease in 3 studies
*Chagas Disease: Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Bouton, J; Caljon, G; Cardoso Santos, C; Ferreira de Almeida Fiuza, L; Karalic, I; Maes, L; Mazzarella, MA; Soeiro, MNC; Van Calenbergh, S | 1 |
| Avila, A; Avila, JL; Monzón, H; Muñoz, E | 1 |
| Berens, RL; LaFon, SW; Looker, DL; Marr, JJ; Nelson, DJ | 1 |
3 other study(ies) available for 4-aminopyrazolo(3,4-d)pyrimidine and Chagas Disease
| Article | Year |
|---|---|
Revisiting Pyrazolo[3,4-
Topics: Animals; Chagas Disease; Drug Design; Drug Stability; Humans; Leishmania infantum; Male; Mice; Microsomes, Liver; Molecular Structure; Nucleosides; Pyrazoles; Pyrimidines; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi | 2021 |
Trypanosoma cruzi: 4-aminopyrazolopyrimidine in the treatment of experimental Chagas' disease.
Topics: Adenine; Animals; Antiprotozoal Agents; Chagas Disease; Liver; Mice; Mice, Inbred C57BL; Spleen; Trypanosoma cruzi | 1983 |
Efficacy of pyrazolopyrimidine ribonucleosides against Trypanosoma cruzi: studies in vitro and in vivo with sensitive and resistant strains.
Topics: Adenine; Allopurinol; Animals; Antiprotozoal Agents; Chagas Disease; Drug Resistance; Formycins; Inosine; Mice; Mice, Inbred DBA; Ribonucleosides; Thionucleosides; Trypanosoma cruzi | 1984 |