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4-aminopropiophenone and Methemoglobinemia

4-aminopropiophenone has been researched along with Methemoglobinemia in 12 studies

*Methemoglobinemia: The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed) [MeSH]

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19908 (66.67)18.7374
1990's1 (8.33)18.2507
2000's1 (8.33)29.6817
2010's1 (8.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Arrow, J; Brown, S; Hopkins, B; Marks, CA; Trought, K1
BODANSKY, O; TEPPERMAN, J2
BODANSKY, O; JANDORF, BJ; TEPPERMAN, J1
Eason, CT; Hix, S; Macmorran, DB; Murphy, EC1
Bauman, RA; Widholm, JJ1
Marrs, TC; Scawin, JW; Swanston, DW1
Guertler, AT; Lagutchik, MS; Martin, DG1
Huang, RH; Liu, LT1
Bright, JE; Marrs, TC2
Bright, JE; Marrs, TC; Wood, SG; Woodman, AC1

Other Studies

12 other study(ies) available for 4-aminopropiophenone and Methemoglobinemia

ArticleYear
Monitoring methaemoglobinaemia in birds using 5 μL of whole blood.
    PloS one, 2023, Volume: 18, Issue:3

    Topics: Animals; Hemoglobins; Methemoglobin; Methemoglobinemia; Mustelidae; Propiophenones

2023
The role of hepatic detoxification in p-aminopropiophenone induced methemoglobinemia.
    The Journal of pharmacology and experimental therapeutics, 1946, Volume: 88, Issue:3

    Topics: Hemoglobins; Inactivation, Metabolic; Liver; Methemoglobinemia; Propiophenones

1946
The effect of para-aminopropiophenone-induced methemoglobinemia on oxygenation of working muscle in human subjects.
    The American journal of physiology, 1946, Volume: 146

    Topics: Cell Respiration; Hemoglobins; Humans; Methemoglobinemia; Muscles; Propiophenones

1946
Effect of p-aminopropiophenone induced methemoglobinemia on the oxygenation of working muscle in human subjects.
    Federation proceedings, 1946, Volume: 5, Issue:1 Pt 2

    Topics: Cell Respiration; Hemoglobins; Humans; Methemoglobinemia; Muscles; Oxygen; Oxygen Consumption; Propiophenones; Respiration; Tissues

1946
Development of a new humane toxin for predator control in New Zealand.
    Integrative zoology, 2010, Volume: 5, Issue:1

    Topics: Animal Welfare; Animals; Cats; Methemoglobinemia; Mustelidae; New Zealand; Pest Control; Pesticides; Propiophenones; Regression Analysis; Time Factors

2010
Operant leverpressing and wheelrunning were differentially reduced by PAPP (p-aminopropiophenone)-induced methemoglobinemia.
    Pharmacology, biochemistry, and behavior, 2007, Volume: 87, Issue:4

    Topics: Algorithms; Animals; Area Under Curve; Body Weight; Conditioning, Operant; Darkness; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Kinetics; Light; Male; Methemoglobin; Methemoglobinemia; Motor Activity; Muscle, Skeletal; Oxygen Consumption; Propiophenones; Rats; Rats, Sprague-Dawley

2007
The acute oral and intravenous toxicity of p-aminopropiophenone (PAPP) to laboratory rodents.
    Toxicology letters, 1984, Volume: 23, Issue:3

    Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Female; Guinea Pigs; Heinz Bodies; Injections, Intravenous; Lethal Dose 50; Male; Methemoglobinemia; Mice; Propiophenones; Rats; Time Factors

1984
Topical anesthetic-induced methemoglobinemia in sheep: a comparison of benzocaine and lidocaine.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1992, Volume: 18, Issue:2

    Topics: Administration, Topical; Anesthesia; Animals; Benzocaine; Dose-Response Relationship, Drug; Female; Hemoglobins; Lidocaine; Methemoglobin; Methemoglobinemia; Propiophenones; Radiation-Protective Agents; Sheep

1992
[Pharmacokinetics and pharmacodynamics of p-aminopropiophenone in rabbits].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1988, Volume: 9, Issue:2

    Topics: Animals; Female; Male; Methemoglobinemia; Propiophenones; Rabbits; Sodium Cyanide

1988
Kinetics of methaemoglobin production. (1). Kinetics of methaemoglobinaemia induced by the cyanide antidotes, p-aminopropiophenone, p-hydroxyaminopropiophenone or p-dimethylaminophenol after intravenous administration.
    Human toxicology, 1986, Volume: 5, Issue:5

    Topics: Aminophenols; Animals; Antidotes; Computer Simulation; Cyanides; Dogs; Female; Injections, Intravenous; Kinetics; Methemoglobin; Methemoglobinemia; Models, Biological; Propiophenones

1986
Kinetics of methaemoglobin production. (2). Kinetics of the cyanide antidote p-aminopropiophenone during oral administration.
    Human toxicology, 1986, Volume: 5, Issue:5

    Topics: Administration, Oral; Animals; Computer Simulation; Cyanides; Dogs; Female; Kinetics; Methemoglobin; Methemoglobinemia; Models, Biological; Propiophenones

1986
Sex differences in the production of methaemoglobinaemia by 4-aminopropiophenone.
    Xenobiotica; the fate of foreign compounds in biological systems, 1987, Volume: 17, Issue:1

    Topics: Animals; Dogs; Dose-Response Relationship, Drug; Female; Male; Methemoglobinemia; Propiophenones

1987