4-aminophenol has been researched along with Methemoglobinemia in 4 studies
4-aminophenol: RN given refers to parent cpd
4-aminophenol : An amino phenol (one of the three possible isomers) which has the single amino substituent located para to the phenolic -OH group.
Methemoglobinemia: The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methemoglobinemia after aniline and certain aniline derivatives is thought to be mediated by toxic metabolites formed during the hepatic clearance of the parent compounds." | 7.67 | Contribution of aniline metabolites to aniline-induced methemoglobinemia. ( Harrison, JH; Jollow, DJ, 1987) |
| "Methemoglobinemia after aniline and certain aniline derivatives is thought to be mediated by toxic metabolites formed during the hepatic clearance of the parent compounds." | 3.67 | Contribution of aniline metabolites to aniline-induced methemoglobinemia. ( Harrison, JH; Jollow, DJ, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| GREENBERG, LA | 1 |
| LESTER, D | 1 |
| McConkey, SE | 1 |
| Grant, DM | 1 |
| Cribb, AE | 1 |
| IKEDA, M | 1 |
| KITA, A | 1 |
| Harrison, JH | 1 |
| Jollow, DJ | 1 |
4 other studies available for 4-aminophenol and Methemoglobinemia
| Article | Year |
|---|---|
The metabolic fate of acetanilid and other aniline derivatives; the role of p-aminophenol in the production of methemoglobinemia after acetanilid.
Topics: Acetanilides; Aminophenols; Aniline Compounds; Methemoglobinemia | 1947 |
The role of para-aminophenol in acetaminophen-induced methemoglobinemia in dogs and cats.
Topics: Acetaminophen; Acetyltransferases; Aminophenols; Animals; Cat Diseases; Cats; Dog Diseases; Dogs; Do | 2009 |
EXCRETION OF P-NITROPHENOL AND P-AMINOPHENOL IN THE URINE OF A PATIENT EXPOSED TO NITROBENZENE.
Topics: Alanine Transaminase; Alkaline Phosphatase; Aminophenols; Aspartate Aminotransferases; Bilirubin; Bl | 1964 |
Contribution of aniline metabolites to aniline-induced methemoglobinemia.
Topics: Aminophenols; Aniline Compounds; Animals; Erythrocytes; Hydroxylamines; Kinetics; Male; Methemoglobi | 1987 |