4-aminophenol has been researched along with Melanoma in 3 studies
4-aminophenol: RN given refers to parent cpd
4-aminophenol : An amino phenol (one of the three possible isomers) which has the single amino substituent located para to the phenolic -OH group.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "New tyrosinase-targeted compounds based on structural variants of the prototype unit 4-aminophenol have been synthesized and screened for their potential as antitumour agents against malignant melanoma." | 7.68 | Synthesis and cytotoxic properties of new N-substituted 4-aminophenol derivatives with a potential as antimelanoma agents. ( d'Ischia, M; Ghanem, G; Lejeune, F; Mascagna, D; Misuraca, G; Morandini, R; Prota, G, 1992) |
| "New tyrosinase-targeted compounds based on structural variants of the prototype unit 4-aminophenol have been synthesized and screened for their potential as antitumour agents against malignant melanoma." | 3.68 | Synthesis and cytotoxic properties of new N-substituted 4-aminophenol derivatives with a potential as antimelanoma agents. ( d'Ischia, M; Ghanem, G; Lejeune, F; Mascagna, D; Misuraca, G; Morandini, R; Prota, G, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yan, S | 1 |
| Huang, R | 1 |
| Wang, C | 1 |
| Zhou, Y | 1 |
| Wang, J | 1 |
| Fu, B | 1 |
| Weng, X | 1 |
| Zhou, X | 1 |
| Knaggs, S | 1 |
| Malkin, H | 1 |
| Osborn, HM | 1 |
| Williams, NA | 1 |
| Yaqoob, P | 1 |
| Mascagna, D | 1 |
| Ghanem, G | 1 |
| Morandini, R | 1 |
| d'Ischia, M | 1 |
| Misuraca, G | 1 |
| Lejeune, F | 1 |
| Prota, G | 1 |
3 other studies available for 4-aminophenol and Melanoma
| Article | Year |
|---|---|
A two-photon fluorescent probe for intracellular detection of tyrosinase activity.
Topics: 2-Naphthylamine; Aminophenols; Cell Line, Tumor; Enzyme Activation; Enzyme Assays; Fluorescent Dyes; | 2012 |
New prodrugs derived from 6-aminodopamine and 4-aminophenol as candidates for melanocyte-directed enzyme prodrug therapy (MDEPT).
Topics: Aminophenols; Cell Line, Tumor; Cell Survival; Dopamine; Drug Delivery Systems; Drug Screening Assay | 2005 |
Synthesis and cytotoxic properties of new N-substituted 4-aminophenol derivatives with a potential as antimelanoma agents.
Topics: Aminophenols; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Screening Assays, Antitumor; Fib | 1992 |