Page last updated: 2024-10-17
4-aminophenol and Ache
4-aminophenol has been researched along with Ache in 3 studies
4-aminophenol: RN given refers to parent cpd
4-aminophenol : An amino phenol (one of the three possible isomers) which has the single amino substituent located para to the phenolic -OH group.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Paracetamol, one of the most widely used pain-relieving drugs, is deacetylated to 4-aminophenol (4-AP) that undergoes fatty acid amide hydrolase (FAAH)-dependent biotransformation into N-arachidonoylphenolamine (AM404), which mediates TRPV1-dependent antinociception in the brain of rodents." | 4.02 | Paracetamol analogues conjugated by FAAH induce TRPV1-mediated antinociception without causing acute liver toxicity. ( Å Nilsson, JL; Blomgren, A; Blomqvist, A; Boudieu, L; Eschalier, A; Grundemar, L; Mallet, C; Nilsson, UJ; Shionoya, K; Sundin, AP; Zygmunt, PM, 2021) |
| "Acetaminophen itself was not toxic to developing mouse cortical neurons at therapeutic concentrations of 10-250 μg/ml." | 1.38 | Effects of the analgesic acetaminophen (Paracetamol) and its para-aminophenol metabolite on viability of mouse-cultured cortical neurons. ( DeSilva, M; Gu, TT; Qiang, M; Schultz, S; Whang, K, 2012) |
Research
Studies (3)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Å Nilsson, JL | 1 |
| Mallet, C | 1 |
| Shionoya, K | 1 |
| Blomgren, A | 1 |
| Sundin, AP | 1 |
| Grundemar, L | 1 |
| Boudieu, L | 1 |
| Blomqvist, A | 1 |
| Eschalier, A | 1 |
| Nilsson, UJ | 1 |
| Zygmunt, PM | 1 |
| Schultz, S | 1 |
| DeSilva, M | 1 |
| Gu, TT | 1 |
| Qiang, M | 1 |
| Whang, K | 1 |
| Terezhalmy, GT | 1 |
| Bowen, LL | 1 |
| Rye, LA | 1 |
Reviews
1 review available for 4-aminophenol and Ache
| Article | Year |
|---|---|
Pharmacotherapeutics in urgent dental care.
Topics: Aminophenols; Anesthetics, Local; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anxiety; Aspirin; | 1986 |
Other Studies
2 other studies available for 4-aminophenol and Ache
| Article | Year |
|---|---|
Paracetamol analogues conjugated by FAAH induce TRPV1-mediated antinociception without causing acute liver toxicity.
Topics: Acetaminophen; Amidohydrolases; Aminophenols; Analgesics; Animals; Antipyretics; Arachidonic Acids; | 2021 |
Effects of the analgesic acetaminophen (Paracetamol) and its para-aminophenol metabolite on viability of mouse-cultured cortical neurons.
Topics: Acetaminophen; Aminophenols; Analgesics; Animals; Brain; Cell Survival; Cells, Cultured; Mice; Mice, | 2012 |