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4-aminophenol and Ache

4-aminophenol has been researched along with Ache in 3 studies

4-aminophenol: RN given refers to parent cpd
4-aminophenol : An amino phenol (one of the three possible isomers) which has the single amino substituent located para to the phenolic -OH group.

Research Excerpts

ExcerptRelevanceReference
"Paracetamol, one of the most widely used pain-relieving drugs, is deacetylated to 4-aminophenol (4-AP) that undergoes fatty acid amide hydrolase (FAAH)-dependent biotransformation into N-arachidonoylphenolamine (AM404), which mediates TRPV1-dependent antinociception in the brain of rodents."4.02Paracetamol analogues conjugated by FAAH induce TRPV1-mediated antinociception without causing acute liver toxicity. ( Å Nilsson, JL; Blomgren, A; Blomqvist, A; Boudieu, L; Eschalier, A; Grundemar, L; Mallet, C; Nilsson, UJ; Shionoya, K; Sundin, AP; Zygmunt, PM, 2021)
"Acetaminophen itself was not toxic to developing mouse cortical neurons at therapeutic concentrations of 10-250 μg/ml."1.38Effects of the analgesic acetaminophen (Paracetamol) and its para-aminophenol metabolite on viability of mouse-cultured cortical neurons. ( DeSilva, M; Gu, TT; Qiang, M; Schultz, S; Whang, K, 2012)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Å Nilsson, JL1
Mallet, C1
Shionoya, K1
Blomgren, A1
Sundin, AP1
Grundemar, L1
Boudieu, L1
Blomqvist, A1
Eschalier, A1
Nilsson, UJ1
Zygmunt, PM1
Schultz, S1
DeSilva, M1
Gu, TT1
Qiang, M1
Whang, K1
Terezhalmy, GT1
Bowen, LL1
Rye, LA1

Reviews

1 review available for 4-aminophenol and Ache

ArticleYear
Pharmacotherapeutics in urgent dental care.
    Dental clinics of North America, 1986, Volume: 30, Issue:3

    Topics: Aminophenols; Anesthetics, Local; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anxiety; Aspirin;

1986

Other Studies

2 other studies available for 4-aminophenol and Ache

ArticleYear
Paracetamol analogues conjugated by FAAH induce TRPV1-mediated antinociception without causing acute liver toxicity.
    European journal of medicinal chemistry, 2021, Mar-05, Volume: 213

    Topics: Acetaminophen; Amidohydrolases; Aminophenols; Analgesics; Animals; Antipyretics; Arachidonic Acids;

2021
Effects of the analgesic acetaminophen (Paracetamol) and its para-aminophenol metabolite on viability of mouse-cultured cortical neurons.
    Basic & clinical pharmacology & toxicology, 2012, Volume: 110, Issue:2

    Topics: Acetaminophen; Aminophenols; Analgesics; Animals; Brain; Cell Survival; Cells, Cultured; Mice; Mice,

2012