4-aminobenzoic acid has been researched along with Granulocytic Leukemia, Chronic in 1 studies
para-Aminobenzoates: Benzoic acids, salts, or esters that contain an amino group attached to carbon number 4 of the benzene ring structure.
4-aminobenzoate : An aromatic amino-acid anion that is the conjugate base of 4-aminobenzoic acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, pharmacokinetic studies in murine models (CD-1 mice) revealed that both SH-4-054 and SH-5-007 are susceptible to glutathione conjugation at the para position of the pentafluorophenyl group via nucleophilic aromatic substitution (SN Ar)." | 1.43 | Disarming an Electrophilic Warhead: Retaining Potency in Tyrosine Kinase Inhibitor (TKI)-Resistant CML Lines While Circumventing Pharmacokinetic Liabilities. ( Ali, AM; Ball, DP; de Araujo, ED; Deininger, MW; Eiring, AM; Gómez-Biagi, RF; Gunning, PT; Heaton, WL; Lai, PS; O'Hare, T; Park, JS; Patel, AB; Rosa, DA; Shouksmith, AE; Vellore, NA, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ali, AM | 1 |
| Gómez-Biagi, RF | 1 |
| Rosa, DA | 1 |
| Lai, PS | 1 |
| Heaton, WL | 1 |
| Park, JS | 1 |
| Eiring, AM | 1 |
| Vellore, NA | 1 |
| de Araujo, ED | 1 |
| Ball, DP | 1 |
| Shouksmith, AE | 1 |
| Patel, AB | 1 |
| Deininger, MW | 1 |
| O'Hare, T | 1 |
| Gunning, PT | 1 |
1 other study available for 4-aminobenzoic acid and Granulocytic Leukemia, Chronic
| Article | Year |
|---|---|
Disarming an Electrophilic Warhead: Retaining Potency in Tyrosine Kinase Inhibitor (TKI)-Resistant CML Lines While Circumventing Pharmacokinetic Liabilities.
Topics: Animals; Antineoplastic Agents; Biological Availability; Cell Line, Tumor; Cell Proliferation; Dose- | 2016 |