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4-aminobenzoic acid and Carcinogenesis

4-aminobenzoic acid has been researched along with Carcinogenesis in 2 studies

para-Aminobenzoates: Benzoic acids, salts, or esters that contain an amino group attached to carbon number 4 of the benzene ring structure.
4-aminobenzoate : An aromatic amino-acid anion that is the conjugate base of 4-aminobenzoic acid.

Carcinogenesis: The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.

Research Excerpts

ExcerptRelevanceReference
"In patients with lung cancer, tankyrase levels negatively correlate with p-AMPK levels and poor survival."1.51Tankyrase disrupts metabolic homeostasis and promotes tumorigenesis by inhibiting LKB1-AMPK signalling. ( Chen, J; Chen, Z; Deng, W; Fong, LWR; Hung, MC; Jiang, W; Li, N; Li, X; Lin, SH; Neri, S; Qiao, Y; Stephan, C; Wang, Y; Ye, R; Yu, Y; Zhang, S; Zhen, Y, 2019)
" Here we tested two orally bioavailable small molecule inhibitors of PAI-1 (TM5275 and TM5441) for their efficacy in pre-clinical models of cancer."1.42Small Molecule Inhibitors of Plasminogen Activator Inhibitor-1 Elicit Anti-Tumorigenic and Anti-Angiogenic Activity. ( DeClerck, YA; Ichimura, A; Miyata, T; Placencio, VR, 2015)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, N1
Wang, Y1
Neri, S1
Zhen, Y1
Fong, LWR1
Qiao, Y1
Li, X1
Chen, Z1
Stephan, C1
Deng, W1
Ye, R1
Jiang, W1
Zhang, S1
Yu, Y1
Hung, MC1
Chen, J1
Lin, SH1
Placencio, VR1
Ichimura, A1
Miyata, T1
DeClerck, YA1

Other Studies

2 other studies available for 4-aminobenzoic acid and Carcinogenesis

ArticleYear
Tankyrase disrupts metabolic homeostasis and promotes tumorigenesis by inhibiting LKB1-AMPK signalling.
    Nature communications, 2019, 09-25, Volume: 10, Issue:1

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Carcinogenesis; Cell L

2019
Small Molecule Inhibitors of Plasminogen Activator Inhibitor-1 Elicit Anti-Tumorigenic and Anti-Angiogenic Activity.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Carcinogenesis; Cell Line, Tumor

2015