4-aminobenzoic acid has been researched along with Carcinogenesis in 2 studies
para-Aminobenzoates: Benzoic acids, salts, or esters that contain an amino group attached to carbon number 4 of the benzene ring structure.
4-aminobenzoate : An aromatic amino-acid anion that is the conjugate base of 4-aminobenzoic acid.
Carcinogenesis: The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In patients with lung cancer, tankyrase levels negatively correlate with p-AMPK levels and poor survival." | 1.51 | Tankyrase disrupts metabolic homeostasis and promotes tumorigenesis by inhibiting LKB1-AMPK signalling. ( Chen, J; Chen, Z; Deng, W; Fong, LWR; Hung, MC; Jiang, W; Li, N; Li, X; Lin, SH; Neri, S; Qiao, Y; Stephan, C; Wang, Y; Ye, R; Yu, Y; Zhang, S; Zhen, Y, 2019) |
| " Here we tested two orally bioavailable small molecule inhibitors of PAI-1 (TM5275 and TM5441) for their efficacy in pre-clinical models of cancer." | 1.42 | Small Molecule Inhibitors of Plasminogen Activator Inhibitor-1 Elicit Anti-Tumorigenic and Anti-Angiogenic Activity. ( DeClerck, YA; Ichimura, A; Miyata, T; Placencio, VR, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, N | 1 |
| Wang, Y | 1 |
| Neri, S | 1 |
| Zhen, Y | 1 |
| Fong, LWR | 1 |
| Qiao, Y | 1 |
| Li, X | 1 |
| Chen, Z | 1 |
| Stephan, C | 1 |
| Deng, W | 1 |
| Ye, R | 1 |
| Jiang, W | 1 |
| Zhang, S | 1 |
| Yu, Y | 1 |
| Hung, MC | 1 |
| Chen, J | 1 |
| Lin, SH | 1 |
| Placencio, VR | 1 |
| Ichimura, A | 1 |
| Miyata, T | 1 |
| DeClerck, YA | 1 |
2 other studies available for 4-aminobenzoic acid and Carcinogenesis
| Article | Year |
|---|---|
Tankyrase disrupts metabolic homeostasis and promotes tumorigenesis by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Carcinogenesis; Cell L | 2019 |
Small Molecule Inhibitors of Plasminogen Activator Inhibitor-1 Elicit Anti-Tumorigenic and Anti-Angiogenic Activity.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Carcinogenesis; Cell Line, Tumor | 2015 |