4-aminobenzoic acid has been researched along with Astrocytoma, Grade IV in 4 studies
para-Aminobenzoates: Benzoic acids, salts, or esters that contain an amino group attached to carbon number 4 of the benzene ring structure.
4-aminobenzoate : An aromatic amino-acid anion that is the conjugate base of 4-aminobenzoic acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study examined the mouse double minute 2 (MDM2) inhibitor RG7388 together with radiotherapy and analyzed strategies to overcome acquired MDM2 inhibitor resistance in glioblastoma." | 7.91 | Targeting Resistance against the MDM2 Inhibitor RG7388 in Glioblastoma Cells by the MEK Inhibitor Trametinib. ( Bendszus, M; Berberich, A; Breckwoldt, MO; Ciprut, S; Fischer, M; Hielscher, T; Hucke, N; Kessler, T; Lemke, D; Oezen, I; Platten, M; Pusch, S; Ruebmann, P; Sahm, F; Schmitt, LM; Thomé, CM; von Deimling, A; Wick, W, 2019) |
| "Even with aggressive treatment involving radiation therapy plus temozolomide (TMZ), the prognosis for glioblastoma remains poor." | 7.83 | Inhibition of STAT3 enhances the radiosensitizing effect of temozolomide in glioblastoma cells in vitro and in vivo. ( Cho, BJ; Choi, EJ; Han, TJ; Kim, DH; Kim, IA; Paek, SH; Song, SH, 2016) |
| "Glioblastoma (GBM) is a malignant brain tumor with a poor long-term prognosis due to recurrence from highly resistant GBM cancer stem cells (CSCs), for which the current standard of treatment with temozolomide (TMZ) alone will unlikely produce a viable cure." | 4.02 | Development of CD133 Targeting Multi-Drug Polymer Micellar Nanoparticles for Glioblastoma - In Vitro Evaluation in Glioblastoma Stem Cells. ( Ayyagari, P; Das, SK; Pollok, KE; Shannon, HE; Smiley, SB; Vannier, MW; Veronesi, MC; Yun, Y, 2021) |
| " This study examined the mouse double minute 2 (MDM2) inhibitor RG7388 together with radiotherapy and analyzed strategies to overcome acquired MDM2 inhibitor resistance in glioblastoma." | 3.91 | Targeting Resistance against the MDM2 Inhibitor RG7388 in Glioblastoma Cells by the MEK Inhibitor Trametinib. ( Bendszus, M; Berberich, A; Breckwoldt, MO; Ciprut, S; Fischer, M; Hielscher, T; Hucke, N; Kessler, T; Lemke, D; Oezen, I; Platten, M; Pusch, S; Ruebmann, P; Sahm, F; Schmitt, LM; Thomé, CM; von Deimling, A; Wick, W, 2019) |
| "Even with aggressive treatment involving radiation therapy plus temozolomide (TMZ), the prognosis for glioblastoma remains poor." | 3.83 | Inhibition of STAT3 enhances the radiosensitizing effect of temozolomide in glioblastoma cells in vitro and in vivo. ( Cho, BJ; Choi, EJ; Han, TJ; Kim, DH; Kim, IA; Paek, SH; Song, SH, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Smiley, SB | 1 |
| Yun, Y | 1 |
| Ayyagari, P | 1 |
| Shannon, HE | 1 |
| Pollok, KE | 2 |
| Vannier, MW | 1 |
| Das, SK | 1 |
| Veronesi, MC | 1 |
| Herrera-Perez, RM | 1 |
| Voytik-Harbin, SL | 1 |
| Sarkaria, JN | 1 |
| Fishel, ML | 1 |
| Rickus, JL | 1 |
| Berberich, A | 1 |
| Kessler, T | 1 |
| Thomé, CM | 1 |
| Pusch, S | 1 |
| Hielscher, T | 1 |
| Sahm, F | 1 |
| Oezen, I | 1 |
| Schmitt, LM | 1 |
| Ciprut, S | 1 |
| Hucke, N | 1 |
| Ruebmann, P | 1 |
| Fischer, M | 1 |
| Lemke, D | 1 |
| Breckwoldt, MO | 1 |
| von Deimling, A | 1 |
| Bendszus, M | 1 |
| Platten, M | 1 |
| Wick, W | 1 |
| Han, TJ | 1 |
| Cho, BJ | 1 |
| Choi, EJ | 1 |
| Kim, DH | 1 |
| Song, SH | 1 |
| Paek, SH | 1 |
| Kim, IA | 1 |
4 other studies available for 4-aminobenzoic acid and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Development of CD133 Targeting Multi-Drug Polymer Micellar Nanoparticles for Glioblastoma - In Vitro Evaluation in Glioblastoma Stem Cells.
Topics: AC133 Antigen; Animals; Brain Neoplasms; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug De | 2021 |
Presence of stromal cells in a bioengineered tumor microenvironment alters glioblastoma migration and response to STAT3 inhibition.
Topics: Bioengineering; Cell Line, Tumor; Cell Movement; Glioblastoma; Humans; Neoplasm Proteins; para-Amino | 2018 |
Targeting Resistance against the MDM2 Inhibitor RG7388 in Glioblastoma Cells by the MEK Inhibitor Trametinib.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Drug Resistance, Neoplasm | 2019 |
Inhibition of STAT3 enhances the radiosensitizing effect of temozolomide in glioblastoma cells in vitro and in vivo.
Topics: Animals; Annexin A5; Apoptosis; Benzoic Acid; Cell Line, Tumor; Cell Movement; Dacarbazine; DNA Modi | 2016 |