4-aminobenzoic acid has been researched along with Alzheimer Disease in 6 studies
para-Aminobenzoates: Benzoic acids, salts, or esters that contain an amino group attached to carbon number 4 of the benzene ring structure.
4-aminobenzoate : An aromatic amino-acid anion that is the conjugate base of 4-aminobenzoic acid.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Flores, J | 2 |
| Noël, A | 2 |
| Foveau, B | 2 |
| Beauchet, O | 1 |
| LeBlanc, AC | 2 |
| Akhter, H | 1 |
| Huang, WT | 1 |
| van Groen, T | 1 |
| Kuo, HC | 1 |
| Miyata, T | 1 |
| Liu, RM | 1 |
| Lynham, J | 1 |
| Lecrux, C | 1 |
| Shrivastava, SK | 1 |
| Sinha, SK | 1 |
| Srivastava, P | 1 |
| Tripathi, PN | 1 |
| Sharma, P | 1 |
| Tripathi, MK | 1 |
| Tripathi, A | 1 |
| Choubey, PK | 1 |
| Waiker, DK | 1 |
| Aggarwal, LM | 1 |
| Dixit, M | 1 |
| Kheruka, SC | 1 |
| Gambhir, S | 1 |
| Shankar, S | 1 |
| Srivastava, RK | 1 |
| Russo, O | 1 |
| Cachard-Chastel, M | 1 |
| Rivière, C | 1 |
| Giner, M | 1 |
| Soulier, JL | 1 |
| Berthouze, M | 1 |
| Richard, T | 1 |
| Monti, JP | 1 |
| Sicsic, S | 1 |
| Lezoualc'h, F | 1 |
| Berque-Bestel, I | 1 |
| Neumaier, B | 1 |
| Deisenhofer, S | 1 |
| Fürst, D | 1 |
| von Arnim, CA | 1 |
| Thees, S | 1 |
| Buck, AK | 1 |
| Glatting, G | 1 |
| Landwehrmeyer, GB | 1 |
| Krause, BJ | 1 |
| Müller, HD | 1 |
| Sommer, C | 1 |
| Reske, SN | 1 |
| Mottaghy, FM | 1 |
6 other studies available for 4-aminobenzoic acid and Alzheimer Disease
| Article | Year |
|---|---|
Pre-symptomatic Caspase-1 inhibitor delays cognitive decline in a mouse model of Alzheimer disease and aging.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Behavior, Animal; Cognitive Dysfunction; C | 2020 |
A Small Molecule Inhibitor of Plasminogen Activator Inhibitor-1 Reduces Brain Amyloid-β Load and Improves Memory in an Animal Model of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Cell Line, | 2018 |
Caspase-1 inhibition alleviates cognitive impairment and neuropathology in an Alzheimer's disease mouse model.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Caspase 1; Caspase Inhibitors; Cognition; | 2018 |
Design and development of novel p-aminobenzoic acid derivatives as potential cholinesterase inhibitors for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Brain; Butyrylcholinesterase; Catalytic Domain; Ch | 2019 |
Design, synthesis, and biological evaluation of new 5-HT4 receptor agonists: application as amyloid cascade modulators and potential therapeutic utility in Alzheimer's disease.
Topics: Alzheimer Disease; Aminobenzoates; Amyloid; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; A | 2009 |
Radiosynthesis and evaluation of [11C]BTA-1 and [11C]3'-Me-BTA-1 as potential radiotracers for in vivo imaging of beta-amyloid plaques.
Topics: 4-Aminobenzoic Acid; Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Biological T | 2007 |