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4-aminobenzoic acid and Alzheimer Disease

4-aminobenzoic acid has been researched along with Alzheimer Disease in 6 studies

para-Aminobenzoates: Benzoic acids, salts, or esters that contain an amino group attached to carbon number 4 of the benzene ring structure.
4-aminobenzoate : An aromatic amino-acid anion that is the conjugate base of 4-aminobenzoic acid.

Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Flores, J2
Noël, A2
Foveau, B2
Beauchet, O1
LeBlanc, AC2
Akhter, H1
Huang, WT1
van Groen, T1
Kuo, HC1
Miyata, T1
Liu, RM1
Lynham, J1
Lecrux, C1
Shrivastava, SK1
Sinha, SK1
Srivastava, P1
Tripathi, PN1
Sharma, P1
Tripathi, MK1
Tripathi, A1
Choubey, PK1
Waiker, DK1
Aggarwal, LM1
Dixit, M1
Kheruka, SC1
Gambhir, S1
Shankar, S1
Srivastava, RK1
Russo, O1
Cachard-Chastel, M1
Rivière, C1
Giner, M1
Soulier, JL1
Berthouze, M1
Richard, T1
Monti, JP1
Sicsic, S1
Lezoualc'h, F1
Berque-Bestel, I1
Neumaier, B1
Deisenhofer, S1
Fürst, D1
von Arnim, CA1
Thees, S1
Buck, AK1
Glatting, G1
Landwehrmeyer, GB1
Krause, BJ1
Müller, HD1
Sommer, C1
Reske, SN1
Mottaghy, FM1

Other Studies

6 other studies available for 4-aminobenzoic acid and Alzheimer Disease

ArticleYear
Pre-symptomatic Caspase-1 inhibitor delays cognitive decline in a mouse model of Alzheimer disease and aging.
    Nature communications, 2020, 09-11, Volume: 11, Issue:1

    Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Behavior, Animal; Cognitive Dysfunction; C

2020
A Small Molecule Inhibitor of Plasminogen Activator Inhibitor-1 Reduces Brain Amyloid-β Load and Improves Memory in an Animal Model of Alzheimer's Disease.
    Journal of Alzheimer's disease : JAD, 2018, Volume: 64, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Cell Line,

2018
Caspase-1 inhibition alleviates cognitive impairment and neuropathology in an Alzheimer's disease mouse model.
    Nature communications, 2018, 09-25, Volume: 9, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Caspase 1; Caspase Inhibitors; Cognition;

2018
Design and development of novel p-aminobenzoic acid derivatives as potential cholinesterase inhibitors for the treatment of Alzheimer's disease.
    Bioorganic chemistry, 2019, Volume: 82

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Brain; Butyrylcholinesterase; Catalytic Domain; Ch

2019
Design, synthesis, and biological evaluation of new 5-HT4 receptor agonists: application as amyloid cascade modulators and potential therapeutic utility in Alzheimer's disease.
    Journal of medicinal chemistry, 2009, Apr-23, Volume: 52, Issue:8

    Topics: Alzheimer Disease; Aminobenzoates; Amyloid; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; A

2009
Radiosynthesis and evaluation of [11C]BTA-1 and [11C]3'-Me-BTA-1 as potential radiotracers for in vivo imaging of beta-amyloid plaques.
    Nuklearmedizin. Nuclear medicine, 2007, Volume: 46, Issue:6

    Topics: 4-Aminobenzoic Acid; Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Biological T

2007