4-aminobenzamidine and Christmas Disease studies

4-aminobenzamidine and Christmas Disease

4-aminobenzamidine: a urokinase inhibitor; inhibits acrosin; structure given in first source

Research Excerpts

Excerpt	Relevance	Reference
"A patient with severe haemophilia B with a glycine-to-valine missense mutation at residue 190 (c25, chymotrypsin numbering) in factor IX (FIX; FIX-G190V or FIX-FuChou) had <1% of normal FIX clotting activity and 36% of normal FIX antigen levels (cross-reacting material- reduced, CRMr)."	1.37	Characterisation of factor IX with a glycine-to-valine missense mutation at residue 190 in a patient with severe haemophilia B. ( Hamaguchi, N; Kao, CY; Kao, JT; Lin, CN; Lin, SW; Shen, MC; Yang, SJ; Yang, YL, 2011)

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (66.67)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (33.33)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

2 (66.67)

18.2507

2000's

0 (0.00)

29.6817

2010's

1 (33.33)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Kao, CY	1
Lin, CN	2
Yang, YL	1
Hamaguchi, N	2
Yang, SJ	1
Shen, MC	2
Kao, JT	1
Lin, SW	2
Smith, KJ	1
Nishimura, H	1
Takeya, H	1
Miyata, T	1
Suehiro, K	1
Okamura, T	1
Niho, Y	1
Iwanaga, S	1

Studies

Kao, CY

Lin, CN

Yang, YL

Hamaguchi, N

Yang, SJ

Shen, MC

Kao, JT

Lin, SW

Smith, KJ

Nishimura, H

Takeya, H

Miyata, T

Suehiro, K

Okamura, T

Niho, Y

Iwanaga, S

Other Studies

3 other studies available for 4-aminobenzamidine and Christmas Disease

Article	Year
Characterisation of factor IX with a glycine-to-valine missense mutation at residue 190 in a patient with severe haemophilia B. Thrombosis and haemostasis, 2011, Volume: 105, Issue:4 Topics: Animals; Benzamidines; Factor IX; Gene Transfer Techniques; Glycine; HEK293 Cells; Hemophilia B; Hum	2011
Characterization of a factor IX variant with a glycine207 to glutamic acid mutation. Blood, 1994, Sep-15, Volume: 84, Issue:6 Topics: Benzamidines; Binding Sites; Calcium; Codon; Computer Simulation; Electrophoresis, Polyacrylamide Ge	1994
Factor IX Fukuoka. Substitution of ASN92 by His in the second epidermal growth factor-like domain results in defective interaction with factors VIIa/X. The Journal of biological chemistry, 1993, Nov-15, Volume: 268, Issue:32 Topics: Adult; Asparagine; Benzamidines; Blood Coagulation Factors; Epidermal Growth Factor; Esterases; Fact	1993

Article

Year

Characterisation of factor IX with a glycine-to-valine missense mutation at residue 190 in a patient with severe haemophilia B.

Thrombosis and haemostasis, 2011, Volume: 105, Issue:4

Topics: Animals; Benzamidines; Factor IX; Gene Transfer Techniques; Glycine; HEK293 Cells; Hemophilia B; Hum

2011

Characterization of a factor IX variant with a glycine207 to glutamic acid mutation.

Blood, 1994, Sep-15, Volume: 84, Issue:6

Topics: Benzamidines; Binding Sites; Calcium; Codon; Computer Simulation; Electrophoresis, Polyacrylamide Ge

1994

Factor IX Fukuoka. Substitution of ASN92 by His in the second epidermal growth factor-like domain results in defective interaction with factors VIIa/X.

The Journal of biological chemistry, 1993, Nov-15, Volume: 268, Issue:32

Topics: Adult; Asparagine; Benzamidines; Blood Coagulation Factors; Epidermal Growth Factor; Esterases; Fact

1993