4-amino-5-hexynoic acid has been researched along with Akinetic-Rigid Variant of Huntington Disease in 1 studies
4-amino-5-hexynoic acid: structure
| Excerpt | Relevance | Reference |
|---|---|---|
| "645), a potent irreversible inhibitor of gamma-aminobutyric acid transaminase, was given orally in various dosage schedules to 14 patients with Huntington disease." | 6.65 | Treatment of Huntington disease with gamma-acetylenic GABA an irreversible inhibitor of GABA-transaminase: increased CSF GABA and homocarnosine without clinical amelioration. ( Agid, Y; Böhlen, P; Bonnet, AM; Chazot, G; Coquillat, G; Fischer, C; Koch-Weser, J; Schechter, PJ; Tell, G, 1981) |
| "645), a potent irreversible inhibitor of gamma-aminobutyric acid transaminase, was given orally in various dosage schedules to 14 patients with Huntington disease." | 2.65 | Treatment of Huntington disease with gamma-acetylenic GABA an irreversible inhibitor of GABA-transaminase: increased CSF GABA and homocarnosine without clinical amelioration. ( Agid, Y; Böhlen, P; Bonnet, AM; Chazot, G; Coquillat, G; Fischer, C; Koch-Weser, J; Schechter, PJ; Tell, G, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tell, G | 1 |
| Böhlen, P | 1 |
| Schechter, PJ | 1 |
| Koch-Weser, J | 1 |
| Agid, Y | 1 |
| Bonnet, AM | 1 |
| Coquillat, G | 1 |
| Chazot, G | 1 |
| Fischer, C | 1 |
1 trial available for 4-amino-5-hexynoic acid and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
Treatment of Huntington disease with gamma-acetylenic GABA an irreversible inhibitor of GABA-transaminase: increased CSF GABA and homocarnosine without clinical amelioration.
Topics: 4-Aminobutyrate Transaminase; Adult; Aged; Alkynes; Aminocaproates; Brain; Brain Chemistry; Carnosin | 1981 |