4-amino-1,8-naphthalimide has been researched along with Breast Neoplasms in 1 studies
4-amino-1,8-naphthalimide: inhibits ADP-ribosylation; sometimes abreviated as 4-AN;
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The purpose of the present study was to investigate the reversal mechanism of doxo resistance by the potent PARP [poly(ADP-ribose) polymerase] inhibitor ANI (4-amino-1,8-naphthalimide) in the p53-deficient breast cancer cell lines EVSA-T and MDA-MB-231." | 3.73 | PARP inhibition sensitizes p53-deficient breast cancer cells to doxorubicin-induced apoptosis. ( Aguilar-Quesada, R; Cañuelo, A; De Murcia, G; Martín-Oliva, D; Muñoz-Gámez, JA; Nuñez, MI; Oliver, FJ; Ruiz de Almodóvar, JM; Valenzuela, MT, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Muñoz-Gámez, JA | 1 |
| Martín-Oliva, D | 1 |
| Aguilar-Quesada, R | 1 |
| Cañuelo, A | 1 |
| Nuñez, MI | 1 |
| Valenzuela, MT | 1 |
| Ruiz de Almodóvar, JM | 1 |
| De Murcia, G | 1 |
| Oliver, FJ | 1 |
1 other study available for 4-amino-1,8-naphthalimide and Breast Neoplasms
| Article | Year |
|---|---|
PARP inhibition sensitizes p53-deficient breast cancer cells to doxorubicin-induced apoptosis.
Topics: 1-Naphthylamine; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Caspase 3; Caspases; Doxor | 2005 |