4-5-epoxymorphinan and Pain

4-5-epoxymorphinan has been researched along with Pain* in 1 studies

Reviews

1 review(s) available for 4-5-epoxymorphinan and Pain

Article	Year
Most recent developments and modifications of 14-alkylamino and 14-alkoxy-4,5-epoxymorphinan derivatives. Mini reviews in medicinal chemistry, 2011, Volume: 11, Issue:12 The 14-position of natural opiates (e.g. morphine) are unsubstituted, however synthetic approaches have uncovered that functionalizing position 14 gives rise to a wide range of diverse activities. This review focuses on SAR of the position, with the aim of aiding in the search for opioid analgesics with improved clinical profiles. Topics: Animals; Humans; Morphinans; Narcotic Antagonists; Pain; Receptors, Opioid; Structure-Activity Relationship	2011

Article

Year

Most recent developments and modifications of 14-alkylamino and 14-alkoxy-4,5-epoxymorphinan derivatives.

Mini reviews in medicinal chemistry, 2011, Volume: 11, Issue:12

The 14-position of natural opiates (e.g. morphine) are unsubstituted, however synthetic approaches have uncovered that functionalizing position 14 gives rise to a wide range of diverse activities. This review focuses on SAR of the position, with the aim of aiding in the search for opioid analgesics with improved clinical profiles.

Topics: Animals; Humans; Morphinans; Narcotic Antagonists; Pain; Receptors, Opioid; Structure-Activity Relationship

2011