4-5-epoxymorphinan has been researched along with Pain* in 1 studies
1 review(s) available for 4-5-epoxymorphinan and Pain
Article | Year |
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Most recent developments and modifications of 14-alkylamino and 14-alkoxy-4,5-epoxymorphinan derivatives.
The 14-position of natural opiates (e.g. morphine) are unsubstituted, however synthetic approaches have uncovered that functionalizing position 14 gives rise to a wide range of diverse activities. This review focuses on SAR of the position, with the aim of aiding in the search for opioid analgesics with improved clinical profiles. Topics: Animals; Humans; Morphinans; Narcotic Antagonists; Pain; Receptors, Opioid; Structure-Activity Relationship | 2011 |