4,5-dioxovaleric acid has been researched along with Porphyrias in 3 studies
*Porphyrias: A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adhikari, A; Bechara, EJ; Britto, LR; Penatti, CA; Resende, RR; Ulrich, H | 1 |
| Di Mascio, P; Dörnemann, D; Medeiros, MH; Onuki, J; Ummus, RE | 1 |
| Cadet, J; Di Mascio, P; Dörnemann, D; Douki, T; Medeiros, MH; Onuki, J; Teixeira, PC | 1 |
3 other study(ies) available for 4,5-dioxovaleric acid and Porphyrias
| Article | Year |
|---|---|
5-Aminolevulinate and 4, 5-dioxovalerate ions decrease GABA(A) receptor density in neuronal cells, synaptosomes and rat brain.
Topics: Aminolevulinic Acid; Animals; Brain; Cell Line; Cell Survival; Humans; Immunohistochemistry; Ions; Male; Neurons; Porphyrias; Rats; Rats, Wistar; Receptors, GABA-A; Synaptosomes; Valerates | 2006 |
Measurement of 4,5-dioxovaleric acid by high-performance liquid chromatography and fluorescence detection.
Topics: Chromatography, High Pressure Liquid; Genetic Carrier Screening; Humans; Mass Spectrometry; Porphyrias; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Valerates | 1999 |
DNA damage by 5-aminolevulinic and 4,5-dioxovaleric acids in the presence of ferritin.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aminolevulinic Acid; Deoxyguanosine; DNA Adducts; DNA Damage; Ferritins; Humans; Mass Spectrometry; Plasmids; Porphyrias; Reactive Oxygen Species; Valerates | 2000 |