4-4-difluoro-4-bora-3a-4a-diaza-s-indacene has been researched along with Triple-Negative-Breast-Neoplasms* in 2 studies
2 other study(ies) available for 4-4-difluoro-4-bora-3a-4a-diaza-s-indacene and Triple-Negative-Breast-Neoplasms
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A mitochondrion-targeted BODIPY-Ir(III) conjugate as a photoinduced ROS generator for the oxidative destruction of triple-negative breast cancer cells.
Photodynamic therapy (PDT) provides an alternative option to root out localized triple-negative breast cancer (TNBC) and has been experiencing a surge of research interest over recent years. In this study, we put forward a paradigm of designing novel transition metal-based PSs with the following characteristics: favorable cell-permeability, significant light-harvesting ability and prominent ROS yield. A novel BODIPY-Ir(III) conjugate has been designed as a photoinduced ROS ( Topics: Antineoplastic Agents; Boron Compounds; Cell Line, Tumor; Cell Proliferation; Coordination Complexes; Drug Screening Assays, Antitumor; Ferric Compounds; Humans; Mitochondria; Molecular Structure; Photochemotherapy; Photosensitizing Agents; Reactive Oxygen Species; Triple Negative Breast Neoplasms | 2021 |
Novel luminescent benzopyranothiophene- and BODIPY-derived aroylhydrazonic ligands and their dicopper(II) complexes: syntheses, antiproliferative activity and cellular uptake studies.
Two novel unsymmetrical binucleating aroylhydrazonic ligands and four dicopper(II) complexes carrying fluorescent benzopyranothiophene (BPT) or boron dipyrromethene (BODIPY) entities were synthesized and fully characterized. Complex 1, derived from the BPT-containing ligand H Topics: Antineoplastic Agents; Boron Compounds; Cell Line, Tumor; Copper; Female; Humans; Microscopy, Fluorescence; Molecular Structure; Thiophenes; Triple Negative Breast Neoplasms | 2021 |