4-4-difluoro-4-bora-3a-4a-diaza-s-indacene and Tauopathies

4-4-difluoro-4-bora-3a-4a-diaza-s-indacene has been researched along with Tauopathies* in 1 studies

Other Studies

1 other study(ies) available for 4-4-difluoro-4-bora-3a-4a-diaza-s-indacene and Tauopathies

Article	Year
Fused Cycloheptatriene-BODIPY Is a High-Performance Near-Infrared Probe to Image Tau Tangles. Journal of medicinal chemistry, 2022, 11-10, Volume: 65, Issue:21 Neurofibrillary tangles (NFTs), which are composed of abnormally hyperphosphorylated Tau, are one of the main pathologic hallmarks of Alzheimer's disease and other tauopathies. The fluorescent imaging probes currently used to target NFTs cannot distinguish them well from β-amyloid plaques, thus limiting their utility to diagnose diseases. Here, we developed a fused cycloheptatriene-BODIPY derivative ( Topics: Alzheimer Disease; Animals; Brain; Disease Models, Animal; Fluorescent Dyes; Mice; Mice, Transgenic; Molecular Docking Simulation; Neurofibrillary Tangles; Plaque, Amyloid; tau Proteins; Tauopathies	2022

Article

Year

Fused Cycloheptatriene-BODIPY Is a High-Performance Near-Infrared Probe to Image Tau Tangles.

Journal of medicinal chemistry, 2022, 11-10, Volume: 65, Issue:21

Neurofibrillary tangles (NFTs), which are composed of abnormally hyperphosphorylated Tau, are one of the main pathologic hallmarks of Alzheimer's disease and other tauopathies. The fluorescent imaging probes currently used to target NFTs cannot distinguish them well from β-amyloid plaques, thus limiting their utility to diagnose diseases. Here, we developed a fused cycloheptatriene-BODIPY derivative (

Topics: Alzheimer Disease; Animals; Brain; Disease Models, Animal; Fluorescent Dyes; Mice; Mice, Transgenic; Molecular Docking Simulation; Neurofibrillary Tangles; Plaque, Amyloid; tau Proteins; Tauopathies

2022