4-4-difluoro-4-bora-3a-4a-diaza-s-indacene has been researched along with Arrhythmias--Cardiac* in 1 studies
1 other study(ies) available for 4-4-difluoro-4-bora-3a-4a-diaza-s-indacene and Arrhythmias--Cardiac
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Red-light-sensitive BODIPY photoprotecting groups for amines and their biological application in controlling heart rhythm.
Control of biological function by the use of photoremovable protecting groups (PPGs) is a gateway towards many new medical developments. Herein, we report the synthesis and application of efficient and biocompatible BODIPY-based photoprotecting groups for amines, which are cleavable with red light in the phototherapeutic window region (λ > 650 nm). We use the most promising PPG for the protection of dopamine and apply it to control the beating frequency of human cardiomyocytes. Topics: Amines; Arrhythmias, Cardiac; Boron Compounds; Humans; Light; Molecular Structure; Myocytes, Cardiac; Photochemical Processes; Phototherapy | 2020 |