4,4'-diphenylmethane diisocyanate has been researched along with Disease Models, Animal in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (23.08) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 6 (46.15) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Vooght, V; Devos, F; Hoet, PH; Nemery, B; Pollaris, L; Seys, S; Vanoirbeek, JA | 1 |
| Pauluhn, J; Poole, A | 1 |
| Gordon, T; Redlich, CA; Wisnewski, AV | 1 |
| Colmsjö, A; Johansson, R; Karlsson, D; Låstbom, L; Melin, J; Nordqvist, Y; Skarping, G | 1 |
| Bloemen, L; Pauluhn, J; Woolhiser, MR | 1 |
| Pauluhn, J | 3 |
| Chang, KC; Karol, MH | 1 |
| Blaikie, L; Botham, PA; Hartop, PJ; Hext, P; Morrow, T; Rattray, NJ; Wilson, AP; Woodcock, D | 1 |
| Baur, X; Marczynski, B; Marek, W; Mensing, T; Potthast, J | 1 |
| Hanada, S; Nishimura, F; Takeoka, A; Tanaka, K | 1 |
| Schaffer, RB; Weyel, DA | 1 |
1 review(s) available for 4,4'-diphenylmethane diisocyanate and Disease Models, Animal
| Article | Year |
|---|---|
Mouse models of diisocyanate asthma.
Topics: Allergens; Animals; Asthma; Cyanates; Disease Models, Animal; Isocyanates; Mice; Models, Biological; Models, Chemical; Toluene 2,4-Diisocyanate | 2002 |
12 other study(ies) available for 4,4'-diphenylmethane diisocyanate and Disease Models, Animal
| Article | Year |
|---|---|
Toluene diisocyanate and methylene diphenyl diisocyanate: asthmatic response and cross-reactivity in a mouse model.
Topics: Air Pollutants, Occupational; Animals; Asthma; Cross Reactions; Disease Models, Animal; Immunoglobulin E; Isocyanates; Male; Mice, Inbred C57BL; Th1-Th2 Balance; Toluene 2,4-Diisocyanate | 2016 |
Brown Norway rat asthma model of diphenylmethane-4,4'-diisocyanate (MDI): determination of the elicitation threshold concentration of after inhalation sensitization.
Topics: Administration, Inhalation; Aerosols; Allergens; Animals; Asthma; Bronchoalveolar Lavage; Disease Models, Animal; Dose-Response Relationship, Drug; Inhalation Exposure; Isocyanates; Lung; Male; Maximum Allowable Concentration; Rats; Rats, Inbred BN | 2011 |
Effects of thermal degradation products from polyurethane foams based on toluene diisocyanate and diphenylmethane diisocyanate on isolated, perfused lung of guinea pig.
Topics: Aerosols; Air Pollutants, Occupational; Animals; Chemical Industry; Disease Models, Animal; Environmental Monitoring; Female; Guinea Pigs; Hot Temperature; Isocyanates; Lung; Male; Perfusion; Polyurethanes; Probability; Risk Assessment; Toluene 2,4-Diisocyanate | 2003 |
Repeated inhalation challenge with diphenylmethane-4,4'-diisocyanate in brown Norway rats leads to a time-related increase of neutrophils in bronchoalveolar lavage after topical induction.
Topics: Administration, Topical; Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Inflammation; Inhalation Exposure; Isocyanates; Lung; Male; Neutrophils; Occupational Exposure; Rats | 2005 |
Brown Norway rat asthma model of diphenylmethane 4,4'-diisocyanate.
Topics: Administration, Inhalation; Animals; Asthma; Bronchoalveolar Lavage; Disease Models, Animal; Humans; Hypersensitivity; Immunoglobulin E; Inflammation; Irritants; Isocyanates; Lung; Rats | 2005 |
Brown Norway rat asthma model of diphenylmethane-4,4'-diisocyanate (MDI): impact of vehicle for topical induction.
Topics: Acetone; Administration, Inhalation; Administration, Topical; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Decanoic Acids; Disease Models, Animal; Isocyanates; L-Lactate Dehydrogenase; Leukocyte Count; Lymph Nodes; Male; Olive Oil; Pharmaceutical Vehicles; Plant Oils; Rats; Rats, Inbred BN; Skin Absorption | 2008 |
Brown Norway rat asthma model of diphenylmethane-4,4'-diisocyanate (MDI): analysis of the elicitation dose-response relationship.
Topics: Administration, Inhalation; Administration, Topical; Allergens; Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Dose-Response Relationship, Drug; Hypersensitivity; Isocyanates; Leukocyte Count; Lung; Male; Neutrophils; Rats; Rats, Inbred BN; Respiratory Function Tests; Skin; Skin Absorption | 2008 |
Diphenylmethane diisocyanate (MDI)-induced asthma: evaluation of the immunologic responses and application of an animal model of isocyanate sensitivity.
Topics: Animals; Antibody Specificity; Asthma; Bronchial Provocation Tests; Cyanates; Disease Models, Animal; Female; Guinea Pigs; Humans; Immunoglobulin E; Intradermal Tests; Isocyanates; Male; Middle Aged; Occupational Diseases | 1984 |
A two-centre study for the evaluation and validation of an animal model for the assessment of the potential of small molecular weight chemicals to cause respiratory allergy.
Topics: Administration, Inhalation; Allergens; Animals; Antibody Specificity; Antigen-Antibody Complex; Dinitrochlorobenzene; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Guinea Pigs; Haptens; Injections, Intradermal; Isocyanates; Male; Molecular Weight; Phthalic Anhydrides; Respiration; Respiratory Hypersensitivity; Serum Albumin; Toluene 2,4-Diisocyanate | 1995 |
Subchronic exposure to diisocyanates increases guinea pig tracheal smooth muscle responses to acetylcholine.
Topics: Acetylcholine; Animals; Culture Techniques; Cyanates; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Guinea Pigs; Isocyanates; Lung Diseases; Muscle Contraction; Muscle, Smooth; Reference Values; Toluene 2,4-Diisocyanate; Trachea | 1999 |
Contact sensitivity induced in mice by methylene bisphenyl diisocyanate.
Topics: Administration, Cutaneous; Animals; Cross Reactions; Cyanates; Dermatitis, Contact; Disease Models, Animal; Hypersensitivity, Delayed; Immunization, Passive; Isocyanates; Male; Mice; Mice, Inbred C57BL; T-Lymphocytes; Toluene 2,4-Diisocyanate | 1987 |
Pulmonary and sensory irritation of diphenylmethane-4,4'- and dicyclohexylmethane-4,4'-diisocyanate.
Topics: Air Pollutants, Occupational; Animals; Cyanates; Disease Models, Animal; Dose-Response Relationship, Drug; Isocyanates; Lung; Lung Diseases; Male; Maximum Allowable Concentration; Mice; Organ Size; Respiration | 1985 |