4,4'-diphenylmethane diisocyanate and Asthma

4,4'-diphenylmethane diisocyanate has been researched along with Asthma in 69 studies

Research

Studies (69)

Timeframe	Studies, this research(%)	All Research%
pre-1990	25 (36.23)	18.7374
1990's	17 (24.64)	18.2507
2000's	20 (28.99)	29.6817
2010's	6 (8.70)	24.3611
2020's	1 (1.45)	2.80

Authors

Authors	Studies
Plehiers, PM; Schupp, T	1
Hettick, JM; Law, BF; Lin, CC; Siegel, PD; Wisnewski, AV	1
De Vooght, V; Devos, F; Hoet, PH; Nemery, B; Pollaris, L; Seys, S; Vanoirbeek, JA	1
Chang, HY; Chen, SH; Jan, RL; Shieh, CC; Wang, JY; Yeh, HJ	1
Choi, GS; Choi, SJ; Hur, GY; Lee, HY; Park, HJ; Park, HS; Sheen, SS; Ye, YM	1
Baur, X	2
Pauluhn, J; Poole, A	1
Dudek, W; Lipińska-Ojrzanowska, A; Pałczyński, C; Swierczyńska-Machura, D; Walusiak-Skorupa, J; Wiszniewska, M; Wittczak, T	1
Bernstein, DI; Boulet, LP; Cartier, A; Cruz, MJ; Fluharty, K; Gautrin, D; Germolec, DR; Johnson, VJ; Kissling, GE; Lummus, ZL; Luster, MI; Malo, JL; Munoz, X; Quirce, S; Sastre, J; Tarlo, SM; Yucesoy, B	1
Gordon, T; Redlich, CA; Wisnewski, AV	1
Liu, Q; Wisnewski, AV	1
Bramé, B; Ferrari, M; Moscato, G; Perfetti, L	1
Kanazawa, M; Kawabata, Y; Kurashima, K; Maeno, Y; Matsushima, H; Sato, N; Sugita, Y; Takayanagi, N; Tokunaga, D; Ubukata, M; Yanagisawa, T	1
Barrantes, OL; Conde-Salazar, L; Valks, R	1
Johnson, VJ; Luster, MI; Matheson, JM	1
Buick, JB; Donnelly, R; Macmahon, J	1
Bloemen, L; Pauluhn, J; Woolhiser, MR	1
Pauluhn, J	3
Bellini, V; Lisi, P; Stingeni, L	1
Choi, GS; Choi, SJ; Hur, GY; Kim, KS; Koh, DH; Park, HJ; Park, HS; Ye, YM	1
Hur, GY; Kang, YM; Kim, KS; Koh, DH; Park, HJ; Park, HS; Sheen, SS; Ye, YM; Yim, HE	1
Filieri, M; Gerosa, F; Paggiaro, P; Pezzini, A; Riviera, A; Spiazzi, A; Toma, G; Tridente, G	1
Bellone, JD; Kanellakes, TM; Levitz, D; Patterson, R; Pruzansky, JJ; Zeiss, CR	1
Baur, X; Fruhmann, G	1
Hurst, DJ	1
Butcher, BT	1
Burge, PS	1
Wang, SR; Wang, SS	1
Chang, KC; Karol, MH	1
Cartier, A; Levitz, D; Malo, JL; Ouimet, G; Zeiss, CR	1
Laitinen, J; Muittari, A; Sovijärvi, A	1
Chan, H; Chan-Yeung, M; Kijek, K; Sherkin, M; Zammit-Tabona, M	1
Harris, KE; Patterson, R; Pruzansky, JJ; Zeiss, CR	1
Boillat, MA; Lob, M	1
Bernstein, DI; Herd, ZL	1
Bonneau, JC	1
Akiyama, N; Arai, Y; Komatsu, T; Miyamoto, Y; Muto, H; Sano, Y; Satoh, F; Tanaka, Y	1
Lenaerts, L; Nemery, B	1
Calcagni, PG; Di Stefano, A; Fabbri, LM; Hosselet, JJ; Maestrelli, P; Mapp, CE; Saetta, M; Santonastaso, A	1
Wen, BY	1
Berman, L; Cullen, M; Miller, PL	1
Bernstein, DI; Bernstein, IL; Bernstein, JA; Herd, ZL; Korbee, L; Scinto, J; Stauder, T	1
Greaves, I; Hall, S; Schoenwetter, WF; Woellner, RC	1
Aliani, M; Carino, M; Ioli, F; Licitra, C; Sarno, N	1
Cartier, A; Leroyer, C; Malo, JL; Perfetti, L	1
Alam, R; Bernstein, DI; Bernstein, JA; Lummus, ZL	1
Aul, DJ; Bhaumik, A; Brown, WE; Kennedy, AL; Lesage, J; Malo, JL	1
Keskinen, HM; Luukkonen, R; Nordman, H; Piirilä, PL; Salo, SP; Tuomi, TO; Tuppurainen, M	1
Husberg, BJ; Lewis, DM; Petsonk, EL; Siegel, PD; Wang, ML	1
Estlander, T; Jolanki, R; Kanerva, L; Keskinen, H	1
Redlich, CA; Wisnewski, AV	1
Baur, X; Czuppon, AB; Hoffarth, HP; Marczynski, B; Marek, W	1
Baur, X; Fruhmann, G; Vogelmeier, C	1
Boccagni, P; Germano, P; Pezzini, A; Spiazzi, A	1
Kennedy, KS; Sales, JH	1
Belin, L; Wass, U	1
Cartier, A; L'Archevêque, J; Malo, JL	1
Cartier, A; Ghezzo, H; Grammer, L; Harris, K; Lagier, F; Malo, JL; Patterson, R	1
Cirla, AM; Innocenti, A; Mariano, A; Pisati, G	1
Boschetto, P; Dal Vecchio, L; Fabbri, LM; Mapp, CE	1
Ito, T; Kudo, T; Miki, T; Shima, S; Tachikawa, S; Yoshida, T	1
Banks, DE; Butcher, BT; Salvaggio, JE	1
Bernstein, IL; Korbee, L	1
Bernstein, DI; Bernstein, IL; Gallagher, JS; Liss, GM; Moller, DR; Stephenson, RL	1
Banks, DE; Barkman, HW; Butcher, BT; Glindmeyer, HW; Hammad, YY; Jones, RN; Rando, RJ; Weill, H	1
Chan, H; Chan-Yeung, M; Johnson, A; Tse, KS	1

Reviews

10 review(s) available for 4,4'-diphenylmethane diisocyanate and Asthma

Article	Year
Absorption, distribution, metabolism, and excretion of methylene diphenyl diisocyanate and toluene diisocyanate: Many similarities and few differences. Toxicology and industrial health, 2022, Volume: 38, Issue:9 Topics: Asthma; Chemical Phenomena; Humans; Isocyanates; Toluene 2,4-Diisocyanate	2022
[Bronchial challenge tests]. Pneumologie (Stuttgart, Germany), 2011, Volume: 65, Issue:6 Topics: Allergens; Alveolitis, Extrinsic Allergic; Asthma; Asthma, Occupational; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Contraindications; Humans; Isocyanates; Methacholine Chloride; Predictive Value of Tests; Respiratory Function Tests	2011
Mouse models of diisocyanate asthma. American journal of respiratory cell and molecular biology, 2002, Volume: 27, Issue:4 Topics: Allergens; Animals; Asthma; Cyanates; Disease Models, Animal; Isocyanates; Mice; Models, Biological; Models, Chemical; Toluene 2,4-Diisocyanate	2002
Recent developments in diisocyanate asthma. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2003, Volume: 90, Issue:5 Suppl 2 Topics: Asthma; Cyanates; Epithelial Cells; Follow-Up Studies; Genetic Predisposition to Disease; Humans; Isocyanates; Lung; Occupational Diseases; Occupational Exposure; Skin; Toluene 2,4-Diisocyanate	2003
Animal models for diisocyanate asthma: answers for lingering questions. Current opinion in allergy and clinical immunology, 2004, Volume: 4, Issue:2 Topics: Air Pollutants, Occupational; Allergens; Animals; Asthma; Cyanates; Humans; Isocyanates; Occupational Diseases	2004
Occupational asthma after exposure to plaster casts containing methylene diphenyl diisocyanate. Occupational medicine (Oxford, England), 2004, Volume: 54, Issue:6 Topics: Adult; Allergens; Asthma; Casts, Surgical; Female; Forced Expiratory Volume; Humans; Isocyanates; Nursing; Occupational Diseases; Occupational Exposure	2004
[Allergy to diphenylmethane diisocyanate: apropos of a case]. Allergie et immunologie, 1994, Volume: 26, Issue:10 Topics: Adult; Allergens; Asthma; Drug Eruptions; Eczema, Dyshidrotic; Female; Humans; Isocyanates; Occupational Diseases; Plasticizers; Plastics; Polyurethanes	1994
Death due to asthma at workplace in a diphenylmethane diisocyanate-sensitized subject. Respiration; international review of thoracic diseases, 1997, Volume: 64, Issue:1 Topics: Acute Disease; Adult; Allergens; Asthma; Fatal Outcome; Humans; Isocyanates; Male; Occupational Diseases; Occupational Exposure; Workplace	1997
Recent developments in diisocyanate asthma. Current opinion in allergy and clinical immunology, 2001, Volume: 1, Issue:2 Topics: Asthma; Cyanates; Genes, MHC Class II; Genetic Predisposition to Disease; Humans; Immunoglobulin E; Immunoglobulin G; Isocyanates; Skin; T-Lymphocytes, Helper-Inducer; Toluene 2,4-Diisocyanate	2001
Isocyanate-induced respiratory disease. Annals of allergy, 1986, Volume: 57, Issue:6 Topics: Asthma; Cyanates; Drug Hypersensitivity; Humans; Isocyanates; Occupational Diseases; Respiratory Hypersensitivity; Respiratory System; Toluene 2,4-Diisocyanate	1986

Other Studies

59 other study(ies) available for 4,4'-diphenylmethane diisocyanate and Asthma

Article	Year
Mass spectrometry-based analysis of murine bronchoalveolar lavage fluid following respiratory exposure to 4,4'-methylene diphenyl diisocyanate aerosol. Xenobiotica; the fate of foreign compounds in biological systems, 2018, Volume: 48, Issue:6 Topics: Aerosols; Animals; Argininosuccinate Synthase; Asthma; Bronchoalveolar Lavage; Cytochrome P-450 Enzyme System; Female; Isocyanates; Mass Spectrometry; Membrane Glycoproteins; Mice; Mice, Inbred BALB C	2018
Toluene diisocyanate and methylene diphenyl diisocyanate: asthmatic response and cross-reactivity in a mouse model. Archives of toxicology, 2016, Volume: 90, Issue:7 Topics: Air Pollutants, Occupational; Animals; Asthma; Cross Reactions; Disease Models, Animal; Immunoglobulin E; Isocyanates; Male; Mice, Inbred C57BL; Th1-Th2 Balance; Toluene 2,4-Diisocyanate	2016
Asthma-like syndrome in school children after accidental exposure to xylene and methylene diphenyl diisocyanate. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2008, Volume: 41, Issue:4 Topics: Adolescent; Asthma; Breath Tests; Chi-Square Distribution; Child; Chromatography, High Pressure Liquid; Female; Humans; Inhalation Exposure; Isocyanates; Male; Respiratory Function Tests; Schools; Xylenes	2008
Serum ferritin and transferrin levels as serologic markers of methylene diphenyl diisocyanate-induced occupational asthma. The Journal of allergy and clinical immunology, 2008, Volume: 122, Issue:4 Topics: Adult; Asthma; Biomarkers; Bronchoalveolar Lavage Fluid; Electrophoresis, Gel, Two-Dimensional; Enzyme-Linked Immunosorbent Assay; Female; Ferritins; Humans; Industry; Isocyanates; Male; Middle Aged; Occupational Exposure; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Transferrin	2008
Brown Norway rat asthma model of diphenylmethane-4,4'-diisocyanate (MDI): determination of the elicitation threshold concentration of after inhalation sensitization. Toxicology, 2011, Mar-15, Volume: 281, Issue:1-3 Topics: Administration, Inhalation; Aerosols; Allergens; Animals; Asthma; Bronchoalveolar Lavage; Disease Models, Animal; Dose-Response Relationship, Drug; Inhalation Exposure; Isocyanates; Lung; Male; Maximum Allowable Concentration; Rats; Rats, Inbred BN	2011
[The real value of diagnostic methods in case of long time of cessation of occupational exposure to diisocyanates among patients diagnosed in the nofer institute of occupational medicine in Łodź]. Medycyna pracy, 2011, Volume: 62, Issue:6 Topics: Adult; Air Pollutants, Occupational; Allergens; Asthma; Humans; Isocyanates; Middle Aged; Occupational Diseases; Occupational Exposure; Poland; Respiratory Function Tests; Retrospective Studies	2011
Genetic variants in antioxidant genes are associated with diisocyanate-induced asthma. Toxicological sciences : an official journal of the Society of Toxicology, 2012, Volume: 129, Issue:1 Topics: Adult; Antioxidants; Asthma; Canada; Cyanates; Female; Genetic Predisposition to Disease; Genetic Variation; Humans; Isocyanates; Male; Toluene 2,4-Diisocyanate	2012
Occupational asthma (OA) with sensitization to diphenylmethane diisocyanate (MDI) presenting at the onset like a reactive airways dysfunction syndrome (RADS). American journal of industrial medicine, 2003, Volume: 44, Issue:3 Topics: Asthma; Diagnosis, Differential; Drug Hypersensitivity; Female; Humans; Industry; Isocyanates; Middle Aged; Occupational Diseases; Respiratory Hypersensitivity	2003
[A case of combined hypersensitivity pneumonitis and bronchial asthma due to isocyanate (MDI)]. Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2003, Volume: 41, Issue:10 Topics: Adult; Alveolitis, Extrinsic Allergic; Asthma; Humans; Isocyanates; Male; Occupational Diseases; Occupational Exposure	2003
Occupational allergic contact urticaria and asthma from diphenylmethane-4,4'-diisocyanatae. Contact dermatitis, 2003, Volume: 49, Issue:3 Topics: Adhesives; Adult; Asthma; Dermatitis, Allergic Contact; Dermatitis, Occupational; Diagnosis, Differential; Emergency Treatment; Female; Humans; Isocyanates; Patch Tests; Urticaria	2003
Repeated inhalation challenge with diphenylmethane-4,4'-diisocyanate in brown Norway rats leads to a time-related increase of neutrophils in bronchoalveolar lavage after topical induction. Inhalation toxicology, 2005, Volume: 17, Issue:2 Topics: Administration, Topical; Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Inflammation; Inhalation Exposure; Isocyanates; Lung; Male; Neutrophils; Occupational Exposure; Rats	2005
Brown Norway rat asthma model of diphenylmethane 4,4'-diisocyanate. Inhalation toxicology, 2005, Dec-01, Volume: 17, Issue:13 Topics: Administration, Inhalation; Animals; Asthma; Bronchoalveolar Lavage; Disease Models, Animal; Humans; Hypersensitivity; Immunoglobulin E; Inflammation; Irritants; Isocyanates; Lung; Rats	2005
Brown Norway rat asthma model of diphenylmethane-4,4'-diisocyanate (MDI): impact of vehicle for topical induction. Regulatory toxicology and pharmacology : RTP, 2008, Volume: 50, Issue:1 Topics: Acetone; Administration, Inhalation; Administration, Topical; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Decanoic Acids; Disease Models, Animal; Isocyanates; L-Lactate Dehydrogenase; Leukocyte Count; Lymph Nodes; Male; Olive Oil; Pharmaceutical Vehicles; Plant Oils; Rats; Rats, Inbred BN; Skin Absorption	2008
Occupational airborne contact urticaria and asthma: simultaneous immediate and delayed allergy to diphenylmethane-4,4'-diisocyanate. Contact dermatitis, 2008, Volume: 58, Issue:2 Topics: Adhesives; Air Pollutants, Occupational; Asthma; Chemical Industry; Dermatitis, Occupational; Humans; Hypersensitivity, Delayed; Isocyanates; Male; Middle Aged; Patch Tests; Urticaria	2008
Clinical and immunologic findings of methylene diphenyl diisocyanate-induced occupational asthma in a car upholstery factory. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2008, Volume: 38, Issue:4 Topics: Adult; Antibodies; Asthma; Automobiles; Environmental Monitoring; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoglobulin E; Immunoglobulin G; Isocyanates; Korea; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Predictive Value of Tests; Prevalence; Reproducibility of Results; Respiratory Tract Diseases; Serum Albumin; Skin Tests; Spirometry; Surveys and Questionnaires	2008
Histamine release and inflammatory cell infiltration in airway Mucosa in methylene diphenyl diisocyanate (MDI)-induced occupational asthma. Journal of clinical immunology, 2008, Volume: 28, Issue:5 Topics: Adult; Asthma; Basophils; Bronchial Provocation Tests; Bronchoscopy; Cell Movement; Cytokines; Female; Histamine Release; Humans; Immunity, Mucosal; Immunohistochemistry; Inflammation Mediators; Isocyanates; Male; Middle Aged; Occupational Exposure; Respiratory Mucosa; Skin Tests; Textile Industry	2008
Brown Norway rat asthma model of diphenylmethane-4,4'-diisocyanate (MDI): analysis of the elicitation dose-response relationship. Toxicological sciences : an official journal of the Society of Toxicology, 2008, Volume: 104, Issue:2 Topics: Administration, Inhalation; Administration, Topical; Allergens; Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Dose-Response Relationship, Drug; Hypersensitivity; Isocyanates; Leukocyte Count; Lung; Male; Neutrophils; Rats; Rats, Inbred BN; Respiratory Function Tests; Skin; Skin Absorption	2008
Specific IgE antibodies in twenty-eight workers with diisocyanate-induced bronchial asthma. Clinical allergy, 1984, Volume: 14, Issue:5 Topics: Asthma; Bronchial Provocation Tests; Cyanates; Female; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Isocyanates; Male; Occupational Diseases; Toluene 2,4-Diisocyanate	1984
Immunoglobulin E-mediated asthma and hypersensitivity pneumonitis with precipitating anti-hapten antibodies due to diphenylmethane diisocyanate (MDI) exposure. The Journal of allergy and clinical immunology, 1980, Volume: 65, Issue:5 Topics: Adult; Alveolitis, Extrinsic Allergic; Antibodies; Asthma; Benzhydryl Compounds; Cross Reactions; Cyanates; Haptens; Humans; Immunoglobulin E; Immunoglobulin G; Isocyanates; Male; Middle Aged; Serum Albumin; Toluene 2,4-Diisocyanate	1980
Specific IgE antibodies in patients with isocyanate asthma. Chest, 1981, Volume: 80, Issue:1 Suppl Topics: Antibodies; Asthma; Benzhydryl Compounds; Cyanates; Humans; Immunoglobulin E; Isocyanates; Toluene 2,4-Diisocyanate	1981
Occupational asthma. The Journal of laboratory and clinical medicine, 1982, Volume: 99, Issue:5 Topics: Animals; Asthma; Bronchi; Cyanates; Dogs; Humans; Isocyanates; Occupational Diseases; Radioallergosorbent Test; Toluene 2,4-Diisocyanate	1982
Immunologic cross-reactivity between different albumin-bound isocyanates. The Journal of allergy and clinical immunology, 1983, Volume: 71, Issue:2 Topics: Adult; Aerosols; Asthma; Cyanates; Drug Hypersensitivity; Humans; Isocyanates; Middle Aged; Occupational Diseases; Radioallergosorbent Test; Serum Albumin; Skin Tests; Toluene 2,4-Diisocyanate	1983
Isocyanate induced asthma. European journal of respiratory diseases. Supplement, 1982, Volume: 123 Topics: Asthma; Bronchial Provocation Tests; Cyanates; Forced Expiratory Volume; Humans; Isocyanates; Occupational Diseases; Toluene 2,4-Diisocyanate	1982
Non-specific bronchial hyper-reactivity in workers exposed to toluene di-isocyanate, diphenyl methane di-isocyanate and colophony. European journal of respiratory diseases. Supplement, 1982, Volume: 123 Topics: Asthma; Bronchi; Cyanates; Electronics; Environmental Exposure; Histamine; Humans; Isocyanates; Occupational Diseases; Resins, Plant; Toluene 2,4-Diisocyanate	1982
[Asthma induced by diphenylmethane diisocyanate]. Zhonghua Minguo wei sheng wu ji mian yi xue za zhi = Chinese journal of microbiology and immunology, 1983, Volume: 16, Issue:1 Topics: Adult; Asthma; Chemical Phenomena; Chemistry; Cyanates; Humans; Isocyanates; Male; Middle Aged; Occupational Diseases; Risk; Toluene 2,4-Diisocyanate	1983
Diphenylmethane diisocyanate (MDI)-induced asthma: evaluation of the immunologic responses and application of an animal model of isocyanate sensitivity. Clinical allergy, 1984, Volume: 14, Issue:4 Topics: Animals; Antibody Specificity; Asthma; Bronchial Provocation Tests; Cyanates; Disease Models, Animal; Female; Guinea Pigs; Humans; Immunoglobulin E; Intradermal Tests; Isocyanates; Male; Middle Aged; Occupational Diseases	1984
Combined alveolitis and asthma due to hexamethylene diisocyanate (HDI), with demonstration of crossed respiratory and immunologic reactivities to diphenylmethane diisocyanate (MDI). The Journal of allergy and clinical immunology, 1983, Volume: 72, Issue:4 Topics: Alveolitis, Extrinsic Allergic; Asthma; Binding Sites, Antibody; Bronchial Provocation Tests; Cross Reactions; Cyanates; Humans; Isocyanates; Male; Middle Aged; Occupational Diseases; Paint; Respiratory Function Tests	1983
[Diisocyanate-induced asthma and alveolitis]. Duodecim; laaketieteellinen aikakauskirja, 1984, Volume: 100, Issue:4 Topics: Adult; Alveolitis, Extrinsic Allergic; Asthma; Construction Materials; Cyanates; Humans; Isocyanates; Male; Occupational Diseases; Paint; Respiratory Function Tests	1984
Asthma caused by diphenylmethane diisocyanate in foundry workers. Clinical, bronchial provocation, and immunologic studies. The American review of respiratory disease, 1983, Volume: 128, Issue:2 Topics: Age Factors; Antibody Specificity; Asthma; Bronchial Provocation Tests; Cyanates; Forced Expiratory Volume; Formaldehyde; Humans; Immunoglobulin E; Immunoglobulin G; Isocyanates; Male; Metallurgy; Methacholine Compounds; Occupational Diseases; Radioallergosorbent Test; Skin Tests; Smoking	1983
An animal model of occupational immunologic asthma due to diphenylmethane diisocyanate, with multiple systemic immunologic responses. The Journal of laboratory and clinical medicine, 1982, Volume: 99, Issue:5 Topics: Airway Resistance; Alveolitis, Extrinsic Allergic; Animals; Antibody Formation; Asthma; Bronchi; Cyanates; Dogs; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin E; Isocyanates; Lymphocytes; Occupational Diseases; Serum Albumin; Serum Albumin, Radio-Iodinated; Skin Tests	1982
[Delayed asthma on diphenylmethane diisocyanate (MDI). The importance of a professional history. The utility and danger of the inhalation tests. Apropos five cases]. Schweizerische medizinische Wochenschrift, 1981, Jan-31, Volume: 111, Issue:5 Topics: Aged; Asthma; Benzhydryl Compounds; Bronchial Provocation Tests; Cyanates; Humans; Isocyanates; Middle Aged; Occupational Diseases; Polyurethanes; Spirometry; Welding	1981
Antigen-specific stimulation of histamine releasing factors in diisocyanate-induced occupational asthma. American journal of respiratory and critical care medicine, 1994, Volume: 150, Issue:4 Topics: Allergens; Antibody Specificity; Asthma; Biomarkers; Biomarkers, Tumor; Cells, Cultured; Dose-Response Relationship, Immunologic; Epitopes; Female; Histamine Release; Humans; Isocyanates; Leukocytes, Mononuclear; Lymphokines; Male; Occupational Diseases; Statistics, Nonparametric; Toluene 2,4-Diisocyanate; Tumor Protein, Translationally-Controlled 1	1994
[A case of suspected occupational asthma in an orthopedist, due to cast materials containing MDI]. Nihon Kyobu Shikkan Gakkai zasshi, 1994, Volume: 32, Issue:6 Topics: Adult; Allergens; Asthma; Casts, Surgical; Humans; Isocyanates; Male; Occupational Diseases; Orthopedics	1994
Exposure to methylene diphenyl diisocyanate in coal mines. Lancet (London, England), 1993, Jan-30, Volume: 341, Issue:8840 Topics: Asthma; Belgium; Coal Mining; Cyanates; Disability Evaluation; Humans; Isocyanates; Male; Occupational Diseases; Occupational Exposure	1993
Sputum eosinophilia after asthmatic responses induced by isocyanates in sensitized subjects. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1994, Volume: 24, Issue:1 Topics: Adult; Aerosols; Asthma; Bronchial Hyperreactivity; Eosinophilia; Female; Humans; Isocyanates; Leukocyte Count; Male; Occupational Diseases; Sputum; Toluene 2,4-Diisocyanate	1994
[An immunological study of workers exposed to diphenylmethane diisocyanate (MDI)]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 1993, Volume: 27, Issue:3 Topics: Adult; Asthma; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoglobulin E; Isocyanates; Male; Middle Aged; Occupational Exposure; Serum Albumin	1993
Automated integration of external databases: a knowledge-based approach to enhancing rule-based expert systems. Computers and biomedical research, an international journal, 1993, Volume: 26, Issue:3 Topics: Artificial Intelligence; Asthma; Cyanates; Database Management Systems; Databases, Bibliographic; Epoxy Resins; Expert Systems; Humans; Isocyanates; Nickel; Occupational Diseases; Online Systems; Phthalic Anhydrides; Software Design	1993
The low prevalence of occupational asthma and antibody-dependent sensitization to diphenylmethane diisocyanate in a plant engineered for minimal exposure to diisocyanates. The Journal of allergy and clinical immunology, 1993, Volume: 92, Issue:3 Topics: Air Pollutants, Occupational; Antibody Formation; Asthma; Cross-Sectional Studies; Cyanates; Environmental Monitoring; Facility Design and Construction; Female; Humans; Isocyanates; Male; Occupational Diseases; Peak Expiratory Flow Rate; Prevalence; Surveys and Questionnaires	1993
Epidemic of asthma in a wood products plant using methylene diphenyl diisocyanate. American journal of industrial medicine, 1997, Volume: 31, Issue:1 Topics: Adult; Asthma; Disease Outbreaks; Female; Humans; Industry; Isocyanates; Male; Middle Aged; Occupational Diseases; Wood	1997
Can reactive airways dysfunction syndrome (RADS) transform into occupational asthma due to "sensitisation" to isocyanates? Thorax, 1998, Volume: 53, Issue:2 Topics: Allergens; Asthma; Bronchial Provocation Tests; Humans; Isocyanates; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Respiratory Hypersensitivity	1998
Diisocyanate antigen-enhanced production of monocyte chemoattractant protein-1, IL-8, and tumor necrosis factor-alpha by peripheral mononuclear cells of workers with occupational asthma. The Journal of allergy and clinical immunology, 1998, Volume: 102, Issue:2 Topics: Adult; Antigens; Asthma; Biomarkers, Tumor; Chemokine CCL2; Chemokines; Cyanates; Female; Humans; Interleukin-8; Isocyanates; Leukocytes, Mononuclear; Lymphokines; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha; Tumor Protein, Translationally-Controlled 1	1998
Specific IgG response to monomeric and polymeric diphenylmethane diisocyanate conjugates in subjects with respiratory reactions to isocyanates. The Journal of allergy and clinical immunology, 1999, Volume: 103, Issue:5 Pt 1 Topics: Adult; Allergens; Antibody Specificity; Asthma; Cross Reactions; Female; Forced Expiratory Volume; Humans; Immunoglobulin G; Isocyanates; Male; Middle Aged; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate	1999
Long-term follow-up of hexamethylene diisocyanate-, diphenylmethane diisocyanate-, and toluene diisocyanate-induced asthma. American journal of respiratory and critical care medicine, 2000, Volume: 162, Issue:2 Pt 1 Topics: Adult; Air Pollutants; Allergens; Asthma; Cyanates; Female; Follow-Up Studies; Humans; Immunoglobulin E; Isocyanates; Male; Surveys and Questionnaires; Toluene 2,4-Diisocyanate	2000
Asthma-like symptoms in wood product plant workers exposed to methylene diphenyl diisocyanate. Chest, 2000, Volume: 118, Issue:4 Topics: Adult; Air Pollutants, Occupational; Allergens; Asthma; Confidence Intervals; Diagnosis, Differential; Female; Humans; Isocyanates; Male; Occupational Diseases; Occupational Exposure; Odds Ratio; Prevalence; Respiratory Function Tests; Retrospective Studies; Surveys and Questionnaires; United States; Wood	2000
Asthma from diisocyanates is not mediated through a Type IV, patch-test-positive mechanism. Contact dermatitis, 2001, Volume: 44, Issue:4 Topics: Adult; Allergens; Asthma; Dermatitis, Allergic Contact; Dermatitis, Occupational; Female; Hand Dermatoses; Humans; Isocyanates; Male; Middle Aged; Paint; Patch Tests; Toluene 2,4-Diisocyanate	2001
DNA damage in human white blood cells after inhalative exposure to methylenediphenyl diisocyanate (MDI)--case report. Toxicology letters, 1992, Volume: 60, Issue:2 Topics: Administration, Inhalation; Asthma; Atmosphere Exposure Chambers; Chromatography, Ion Exchange; Cyanates; DNA; DNA Damage; Electrophoresis, Polyacrylamide Gel; Environmental Exposure; Humans; Isocyanates; Leukocytes; Male; Middle Aged	1992
Isocyanate-induced asthma: results of inhalation tests with TDI, MDI and methacholine. International archives of occupational and environmental health, 1991, Volume: 63, Issue:1 Topics: Asthma; Bronchial Provocation Tests; Cyanates; Female; Humans; Isocyanates; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Respiratory Function Tests; Skin Tests; Toluene 2,4-Diisocyanate	1991
RAST-detection of specific IgE in diphenylmethane diisocyanate exposed workers: considerations in performance of the test. Allergy, 1991, Volume: 46, Issue:3 Topics: Asthma; Cyanates; Humans; Immunoglobulin E; Isocyanates; Ligands; Occupational Diseases; Radioallergosorbent Test; Sensitivity and Specificity; Serum Albumin; Time Factors	1991
Epiglottic dysfunction after isocyanate inhalation exposure. Archives of otolaryngology--head & neck surgery, 1990, Volume: 116, Issue:6 Topics: Adult; Airway Obstruction; Asthma; Cyanates; Epiglottis; Humans; Isocyanates; Male; Occupational Diseases	1990
Immunologic specificity of isocyanate-induced IgE antibodies in serum from 10 sensitized workers. The Journal of allergy and clinical immunology, 1989, Volume: 83, Issue:1 Topics: Antibody Specificity; Asthma; Carrier Proteins; Cyanates; Haptens; Humans; Immunoglobulin E; Isocyanates; Male; Occupational Diseases; Radioallergosorbent Test; Serum Albumin; Toluene 2,4-Diisocyanate	1989
Significant changes in nonspecific bronchial responsiveness after isolated immediate bronchospecific reactions caused by isocyanates but not after a late reaction caused by plicatic acid. The Journal of allergy and clinical immunology, 1989, Volume: 83, Issue:1 Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Cyanates; Forced Expiratory Volume; Histamine; Humans; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Isocyanates; Lignans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Naphthols; Occupational Diseases	1989
Specific serum antibodies against isocyanates: association with occupational asthma. The Journal of allergy and clinical immunology, 1989, Volume: 84, Issue:4 Pt 1 Topics: Antibodies; Asthma; Cyanates; Female; Humans; Immunoglobulin E; Immunoglobulin G; Isocyanates; Male; Occupational Diseases; Skin Tests	1989
Cross-reaction between aromatic isocyanates (TDI and MDI): a specific bronchial provocation test study. Clinical allergy, 1988, Volume: 18, Issue:4 Topics: Adult; Asthma; Bronchial Provocation Tests; Cross Reactions; Cyanates; Female; Humans; Isocyanates; Male; Middle Aged; Occupational Diseases; Polyurethanes; Toluene 2,4-Diisocyanate	1988
Combined asthma and alveolitis due to diphenylmethane diisocyanate (MDI) with demonstration of no crossed respiratory reactivity to toluene diisocyanate (TDI). Annals of allergy, 1985, Volume: 54, Issue:5 Topics: Adult; Alveolitis, Extrinsic Allergic; Asthma; Bronchi; Bronchial Provocation Tests; Cyanates; Female; Forced Expiratory Volume; Humans; Isocyanates; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Neutrophils; Therapeutic Irrigation; Toluene 2,4-Diisocyanate	1985
[Health hazards in workers of small scale polyurethane production factory]. Sangyo igaku. Japanese journal of industrial health, 1986, Volume: 28, Issue:2 Topics: Adolescent; Adult; Aged; Asthma; Chemical Industry; Cyanates; Female; Humans; Isocyanates; Male; Middle Aged; Morbidity; Occupational Diseases; Polyurethanes; Toluene 2,4-Diisocyanate	1986
Workers risk occupational asthma by exposure to myriad of chemicals. Occupational health & safety (Waco, Tex.), 1988, Volume: 57, Issue:3 Topics: Asthma; Bronchial Provocation Tests; Cyanates; Humans; Isocyanates; Male; Occupational Diseases; Recurrence; Respiratory Function Tests	1988
Pulmonary and immunologic evaluation of foundry workers exposed to methylene diphenyldiisocyanate (MDI). The Journal of allergy and clinical immunology, 1988, Volume: 82, Issue:1 Topics: Adult; Alloys; Asthma; Cyanates; Humans; Immunoglobulin E; Isocyanates; Male; Middle Aged; Occupational Diseases; Radioallergosorbent Test; Respiratory Function Tests; Skin Tests; Steel	1988
Absence of hyperresponsiveness to methacholine in a worker with methylene diphenyl diisocyanate (MDI)-induced asthma. Chest, 1986, Volume: 89, Issue:3 Topics: Adult; Asthma; Bronchial Provocation Tests; Cyanates; False Negative Reactions; Forced Expiratory Volume; Humans; Isocyanates; Male; Methacholine Chloride; Methacholine Compounds; Occupational Diseases; Time Factors; Vital Capacity	1986
A study of serum antibody activity in workers with occupational exposure to diphenylmethane diisocyanate. Allergy, 1985, Volume: 40, Issue:5 Topics: Antibodies; Antibody Specificity; Asthma; Cross Reactions; Cyanates; Haptens; Humans; Immunoglobulin E; Immunoglobulin G; Isocyanates; Occupational Diseases; Serum Albumin	1985