Compounds > 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid
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4,4'-diisothiocyanostilbene-2,2'-disulfonic acid and HbS Disease

4,4'-diisothiocyanostilbene-2,2'-disulfonic acid has been researched along with HbS Disease in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's4 (50.00)18.2507
2000's0 (0.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alper, SL; Brugnara, C; Gottlieb, PA; Otterbein, LE; Sachs, F; Shmukler, BE; Trudel, M; Vandorpe, DH; Xu, C1
Ellory, JC; Gibson, JS; Ma, YL; Rees, DC1
Kaji, DM1
Clark, MR; Rossi, ME1
Apovo, M; Beuzard, Y; Giraud, F; Rhoda, MD1
Joiner, CH2
Joiner, CH; Lux, SE; Platt, OS1

Other Studies

8 other study(ies) available for 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid and HbS Disease

ArticleYear
Hypoxia activates a Ca2+-permeable cation conductance sensitive to carbon monoxide and to GsMTx-4 in human and mouse sickle erythrocytes.
    PloS one, 2010, Jan-15, Volume: 5, Issue:1

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Anemia, Sickle Cell; Animals; Calcium; Calcium Channels; Carbon Monoxide; Cell Hypoxia; Dipyridamole; Erythrocyte Membrane; Erythrocytes, Abnormal; Humans; Intercellular Signaling Peptides and Proteins; Mice; Patch-Clamp Techniques; Peptides; Spider Venoms

2010
The conductance of red blood cells from sickle cell patients: ion selectivity and inhibitors.
    The Journal of physiology, 2012, May-01, Volume: 590, Issue:9

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Anemia, Sickle Cell; Benzaldehydes; Calcium; Cell Membrane Permeability; Dose-Response Relationship, Drug; Electric Conductivity; Erythrocyte Membrane; Hemoglobin, Sickle; Humans; Hydrogen-Ion Concentration; Intercellular Signaling Peptides and Proteins; Ion Transport; Magnesium; Manganese; Membrane Potentials; Membrane Transport Modulators; Oxygen; Patch-Clamp Techniques; Peptides; Potassium; Protein Multimerization; Rubidium; Sodium; Spider Venoms; Time Factors

2012
Hemisodium, a novel selective Na ionophore. Effect on normal human erythrocytes.
    The Journal of general physiology, 1992, Volume: 99, Issue:2

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Anemia, Sickle Cell; Biological Transport; Cell Membrane Permeability; Cells, Cultured; Dose-Response Relationship, Drug; Electric Conductivity; Erythrocytes; Erythrocytes, Abnormal; Humans; Ionophores; Kidney Tubules; Osmolar Concentration; Potassium; Sodium

1992
Permeability characteristics of deoxygenated sickle cells.
    Blood, 1990, Nov-15, Volume: 76, Issue:10

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Anemia, Sickle Cell; Arabinose; Cell Membrane Permeability; Chlorides; Cytochalasin B; Diamide; Dose-Response Relationship, Drug; Erythritol; Erythrocyte Membrane; Humans; Mannitol; Ouabain; Oxidation-Reduction; Potassium; Sodium; Sulfates

1990
Ca2+ permeability in deoxygenated sickle cells.
    Blood, 1990, Jun-15, Volume: 75, Issue:12

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Anemia, Sickle Cell; Biological Transport; Calcium; Calcium Channels; Cell Membrane Permeability; Endocytosis; Erythrocyte Membrane; Humans; Nifedipine; Oxygen

1990
Deoxygenation-induced cation fluxes in sickle cells: II. Inhibition by stilbene disulfonates.
    Blood, 1990, Jul-01, Volume: 76, Issue:1

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Anemia, Sickle Cell; Anion Exchange Resins; Benzenesulfonates; Cations; Cell Membrane Permeability; Erythrocytes, Abnormal; Heterozygote; Humans; Isothiocyanates; Oxidation-Reduction; Phloretin; Stilbenes; Thiocyanates; Time Factors

1990
Cation depletion by the sodium pump in red cells with pathologic cation leaks. Sickle cells and xerocytes.
    The Journal of clinical investigation, 1986, Volume: 78, Issue:6

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Anemia, Hemolytic, Congenital; Anemia, Sickle Cell; Biological Transport; Calcium; Dehydration; Erythrocytes; Hemoglobins; Humans; Ion Channels; Ouabain; Potassium; Sodium

1986
Studies on the mechanism of passive cation fluxes activated by deoxygenation of sickle cells.
    Progress in clinical and biological research, 1987, Volume: 240

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Anemia, Sickle Cell; Anion Transport Proteins; Carrier Proteins; Cell Membrane Permeability; Erythrocyte Membrane; Hemoglobin, Sickle; Humans; In Vitro Techniques; Niflumic Acid; Phloretin; Potassium; Sodium; Stilbenes

1987