4,4'-diisothiocyanostilbene-2,2'-disulfonic acid has been researched along with Cystic Fibrosis of Pancreas in 47 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.26) | 18.7374 |
| 1990's | 29 (61.70) | 18.2507 |
| 2000's | 13 (27.66) | 29.6817 |
| 2010's | 3 (6.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| deCourcey, F; Ennis, M; Stott, JB; Zholos, AV | 1 |
| Antigny, F; Becq, F; Blondel, M; Dannhoffer, L; Norez, C; Vandebrouck, C | 1 |
| Garcia, MA; Quinton, PM; Yang, N | 1 |
| Dankó, T; Hakim, H; Hargitai, D; Molnár, M; Pataki, A; Zsembery, A | 1 |
| Li, X; Shen, B; Wang, F; Yang, D; Yao, X | 1 |
| Boucher, RC; Coakley, RD; Paradiso, AM | 1 |
| Almaca, J; Duebbers, A; Falk, S; Haberle, J; Huber, SM; Kunzelmann, K; Oberleithner, H; Schillers, H; Stumpf, A; Walte, M; Wenners-Epping, K | 1 |
| Itani, OA; Lamb, FS; Melvin, JE; Welsh, MJ | 1 |
| Colledge, WH; Evans, MJ; O'Brien, JA; Ratcliff, R; Sepúlveda, FV; Valverde, MA | 1 |
| Abraham, EH; Amara, JF; Ausiello, DA; Cantiello, HF; Ercole, LB; Gregory, RJ; Prat, AG; Reisin, IL | 1 |
| Calayag, C; Matsumoto-Pon, J; Ohrui, T; Skach, W; Thompson, M; Widdicombe, JH | 1 |
| Abraham, EH; Amara, JF; Ausiello, DA; Cantiello, HF; Gregory, RJ; Prat, AG; Reisin, IL | 1 |
| Boucher, RC; Fitz, JG; Paradiso, AM; Stutts, MJ | 1 |
| Allen, SS; Carroll, TP; Cutting, GR; Flotte, TR; Fulmer, SB; Guggino, WB; Morales, MM | 1 |
| Egan, DA; Faller, DP; Ryan, MP | 1 |
| Basavappa, S; Cohn, JA; Fitz, JG; McGill, J; Melhus, O | 1 |
| Berton, G; Cabrini, G; Dechecchi, MC; Tamanini, A | 1 |
| Flezar, M; Heisler, S | 1 |
| Boucher, RC; Gabriel, SE; Gatzy, JT; O'Connell, TL; Olsen, JC; Price, EM; Stutts, MJ | 1 |
| Finkbeiner, WE; Haws, C; Krouse, ME; Moon, S; Widdicombe, JH; Wine, JJ; Xia, Y | 1 |
| Kurokawa, K; Seki, G; Suzuki, K; Taniguchi, S; Uwatoko, S | 1 |
| Cantin, AM | 1 |
| Chan, HC; Fu, LX; Law, SH; Leung, PS; Wong, PY | 1 |
| Colledge, WH; Cuthbert, AW; Evans, MJ; Gill, DR; Higgins, CF; Huang, L; Hyde, SC; MacVinish, LJ; Mofford, KA; Ratcliff, R; Sorgi, F | 1 |
| Finkbeiner, WE; Jiang, C; Miller, SS; Widdicombe, JH | 1 |
| Blank, U; Clauss, W; Lindemann, H; Möller, K; Münker, G; Rieboldt, J; Rückes, C; Weber, WM | 1 |
| Cotton, CU; Drumm, ML; Kelley, TJ | 1 |
| Devidas, S; Egan, ME; Guggino, WB; Morales, MM; Schwiebert, EM | 1 |
| Loffing, J; McCoy, D; Moyer, BD; Stanton, BA | 1 |
| Elble, RC; Fuller, CM; Gruber, AD; Ji, HL; Pauli, BU; Schreur, KD | 1 |
| Clauss, W; Lindemann, H; Münker, G; Rückes-Nilges, C; Weber, U; Weber, WM | 1 |
| Duszyk, M; Thethi, K | 1 |
| Cutting, GR; Macek, M; Mickle, JE; Milewski, MI | 1 |
| Ballmann, M; Bijman, J; Bronsveld, I; Busche, R; De Jonge, HR; Greipel, J; Halley, DJ; Hundrieser, J; Laabs, U; Mekus, F; Tümmler, B; Veeze, HJ | 1 |
| Canny, G; Coakley, RJ; Greally, P; McElvaney, NG; O'Neill, SJ; Taggart, C | 1 |
| Burnham, C; Shull, GE; Shumaker, H; Soleimani, M; Wheat, VJ; Yankaskas, JR | 1 |
| Clarke, LL; Gawenis, LR; Harline, MC; Turner, JT; Walker, NM; Weisman, GA | 1 |
| Boucher, RC; Gabriel, SE; Lethem, MI; Makhlina, M; Martsen, E; Thomas, EJ | 1 |
| Brady, KG; Drumm, ML; Kelley, TJ | 1 |
| Duszyk, M | 1 |
| Boucher, RC; Chinet, TC; Clarke, LL; Fullton, JM; Mason, SJ; Stutts, MJ | 1 |
| Benos, DJ; Cunningham, SA; Frizzell, RA; Worrell, RT | 1 |
| Boucher, RC; Gabriel, SE; Price, EM; Stutts, MJ | 1 |
| Benz, R; Hilschmann, N; Schmid, A; Thinnes, FP | 1 |
| Babel, D; Hein, A; Hilschmann, N; Jürgens, L; König, U; Schmid, A; Thinnes, FP | 1 |
| Martinez, AM; Martinez, JR | 1 |
| Lenaz, G; Romeo, G; Rugolo, M | 1 |
1 review(s) available for 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid and Cystic Fibrosis of Pancreas
| Article | Year |
|---|---|
[A flip-flop model of the chloride channel complex explains the dysregulation of the chloride flow in the plasmalemma of cells in cystic fibrosis].
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Cell Membrane Permeability; Chlorides; Cystic Fibrosis; Humans; Ion Channels; Membrane Lipids; Membrane Proteins; Molecular Weight; Porins; Voltage-Dependent Anion Channel 1; Voltage-Dependent Anion Channels | 1991 |
46 other study(ies) available for 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid and Cystic Fibrosis of Pancreas
| Article | Year |
|---|---|
Functional and pharmacological characterization of volume-regulated anion channels in human normal and cystic fibrosis bronchial and nasal epithelial cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Bronchi; Cell Line; Chloride Channels; Cyclopentanes; Cystic Fibrosis; Epithelial Cells; Humans; Indans; Membrane Transport Modulators; Nasal Mucosa; Nitrobenzoates | 2014 |
Guanabenz, an alpha2-selective adrenergic agonist, activates Ca2+-dependent chloride currents in cystic fibrosis human airway epithelial cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Apoptosis; Calcium; Caspase 3; Cell Line; Cell Survival; Chloride Channel Agonists; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Guanabenz; Humans; Iodides; Membrane Potentials; Patch-Clamp Techniques; Respiratory Mucosa | 2008 |
Normal mouse intestinal mucus release requires cystic fibrosis transmembrane regulator-dependent bicarbonate secretion.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Bicarbonates; Bumetanide; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dinoprostone; Humans; In Vitro Techniques; Intestinal Mucosa; Intestine, Small; Ion Transport; Mice; Mice, Inbred C57BL; Mice, Inbred CFTR; Models, Biological; Mucus; Serotonin; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Bicarbonate Symporters | 2009 |
Extracellular alkalinization stimulates calcium-activated chloride conductance in cystic fibrosis human airway epithelial cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Aniline Compounds; Benzoxazoles; Calcium; Cell Line; Chloride Channels; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Niflumic Acid; Patch-Clamp Techniques; Quinolinium Compounds; Respiratory Mucosa; Xanthenes; Zinc Compounds | 2011 |
A synthetic chloride channel restores chloride conductance in human cystic fibrosis epithelial cells.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Cell Line; Chloride Channels; Chlorides; Cystic Fibrosis; Electrophysiology; Epithelial Cells; Humans; Lipopolysaccharides; Mice; Niflumic Acid; ortho-Aminobenzoates; Tumor Necrosis Factor-alpha | 2012 |
Polarized distribution of HCO3- transport in human normal and cystic fibrosis nasal epithelia.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adult; Amiloride; Barium; Bicarbonates; Biological Transport, Active; Cells, Cultured; Chlorides; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Diffusion Chambers, Culture; Diuretics; Epithelial Cells; Female; Fluoresceins; Fluorometry; Humans; Hydrogen-Ion Concentration; Male; Nasal Mucosa; ortho-Aminobenzoates | 2003 |
IADS, a decomposition product of DIDS activates a cation conductance in Xenopus oocytes and human erythrocytes: new compound for the diagnosis of cystic fibrosis.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Cations; Cystic Fibrosis; Electrophysiology; Erythrocytes; Female; Hemolysis; Humans; Ion Transport; Oocytes; Patch-Clamp Techniques; Xenopus | 2006 |
Basolateral chloride current in human airway epithelia.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Bronchi; Cells, Cultured; Chloride Channels; CLC-2 Chloride Channels; Cyclic AMP; Cystic Fibrosis; Electric Conductivity; Enzyme Activation; Epithelial Cells; Humans; Hydrogen-Ion Concentration; Ion Transport; Mice; Mice, Knockout; Protein Kinase C; Signal Transduction; Trachea | 2007 |
Inactivation of the murine cftr gene abolishes cAMP-mediated but not Ca(2+)-mediated secretagogue-induced volume decrease in small-intestinal crypts.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Calcium; Carbachol; Chloride Channels; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Gene Expression Regulation; Glyburide; Intestine, Small; Membrane Proteins; Mice; Vasoactive Intestinal Peptide | 1993 |
External ATP and its analogs activate the cystic fibrosis transmembrane conductance regulator by a cyclic AMP-independent mechanism.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antimycin A; Cell Line; Chloride Channels; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Kinetics; Mammary Neoplasms, Experimental; Membrane Proteins; Mice; Stereoisomerism; Thionucleotides; Transfection; Tumor Cells, Cultured; Uridine Triphosphate | 1994 |
Radiotracer studies of cystic fibrosis transmembrane conductance regulator expressed in Xenopus oocytes.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Animals; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Electrolytes; Formates; Mannitol; Membrane Proteins; Oocytes; Radioisotopes; Rubidium; Sulfates; Tetradecanoylphorbol Acetate; Xenopus | 1994 |
The cystic fibrosis transmembrane conductance regulator is a dual ATP and chloride channel.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Animals; Chloride Channels; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Ion Transport; Membrane Potentials; Membrane Proteins; Mice; ortho-Aminobenzoates; Transfection; Tumor Cells, Cultured | 1994 |
Multiple modes of regulation of airway epithelial chloride secretion by extracellular ATP.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Calcium; Cells, Cultured; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Egtazic Acid; Extracellular Space; Humans; Intracellular Membranes; Ionomycin; Membrane Proteins; Reference Values; Respiratory System | 1994 |
Alternate translation initiation codons can create functional forms of cystic fibrosis transmembrane conductance regulator.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Base Sequence; Chloride Channels; Codon; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Ion Channel Gating; Membrane Proteins; Molecular Sequence Data; Oocytes; Patch-Clamp Techniques; Peptide Chain Initiation, Translational; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Deletion; Structure-Activity Relationship; Xenopus | 1995 |
Evidence for location of the CFTR in human placental apical membrane vesicles.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Anions; Bumetanide; Cell Membrane; Chloride Channels; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Humans; Immunochemistry; Membrane Proteins; ortho-Aminobenzoates; Placenta; Pregnancy; Time Factors | 1995 |
Regulation of membrane chloride currents in rat bile duct epithelial cells.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Bile Ducts; Calcium; Cells, Cultured; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Epithelium; Iodides; Ionomycin; Kinetics; Liver; Male; Membrane Potentials; Membrane Proteins; Rats; Rats, Sprague-Dawley; Thionucleotides | 1993 |
Protein kinase C activates chloride conductance in C127 cells stably expressing the cystic fibrosis gene.
Topics: 1-Methyl-3-isobutylxanthine; 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Line; Chloride Channels; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Ion Channels; Kinetics; Membrane Proteins; Mice; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Transfection | 1993 |
P2-purinergic receptors in human breast tumor cells: coupling of intracellular calcium signaling to anion secretion.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Breast Neoplasms; Calcium; Chloride Channels; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Humans; Iodine Radioisotopes; Ion Channels; Membrane Proteins; Receptors, Purinergic; RNA, Messenger; Signal Transduction; Tumor Cells, Cultured | 1993 |
Functional consequences of heterologous expression of the cystic fibrosis transmembrane conductance regulator in fibroblasts.
Topics: 3T3 Cells; 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Blotting, Western; Chloride Channels; Chlorides; Clone Cells; Colforsin; Colonic Neoplasms; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Fibroblasts; Humans; Ion Channels; Membrane Potentials; Membrane Proteins; Mice; Recombinant Proteins; Transfection; Tumor Cells, Cultured | 1993 |
CFTR and other Cl- channels in human airway cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Cells, Cultured; Chloride Channels; Cystic Fibrosis; Epithelium; Humans; Patch-Clamp Techniques; Respiratory Physiological Phenomena | 1994 |
Activation of the basolateral Cl- conductance by cyclic AMP in rabbit renal proximal tubule S3 segment.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Chloride Channels; Cyclic AMP; Cystic Fibrosis; Kidney; Microelectrodes; Rabbits | 1994 |
Taurine modulation of hypochlorous acid-induced lung epithelial cell injury in vitro. Role of anion transport.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adult; Aged; Animals; Anions; Bronchitis; Cats; Cell Line; Cystic Fibrosis; Dimethyl Sulfoxide; Epithelium; Female; Humans; Hypochlorous Acid; Lung; Male; Reference Values; Smoking; Taurine; Temperature | 1994 |
Angiotensin II receptor type I-regulated anion secretion in cystic fibrosis pancreatic duct cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Angiotensin II; Angiotensin Receptor Antagonists; Antiporters; Bicarbonates; Biological Transport, Active; Biphenyl Compounds; Calcium; Cell Polarity; Cells, Cultured; Chloride-Bicarbonate Antiporters; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Imidazoles; Intracellular Fluid; Ion Transport; Losartan; Microscopy, Confocal; Nystatin; Pancreatic Ducts; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Secretory Rate; Tetrazoles | 1997 |
Chloride secretion in the trachea of null cystic fibrosis mice: the effects of transfection with pTrial10-CFTR2.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Antioxidants; Avian Sarcoma Viruses; Calcimycin; Chloride Channels; Chlorides; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Diuretics; Genetic Therapy; HeLa Cells; Humans; Hydroquinones; Ionophores; Mice; Mice, Inbred CFTR; Molecular Sequence Data; Plasmids; Promoter Regions, Genetic; Trachea; Transfection | 1997 |
Fluid transport across cultures of human tracheal glands is altered in cystic fibrosis.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Biological Transport, Active; Body Fluids; Cells, Cultured; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Exocrine Glands; Humans; Ion Transport; Methacholine Chloride; Nitrobenzoates; Thionucleotides; Trachea; Uridine Triphosphate | 1997 |
Amiloride-sensitive Na+ channels in human nasal epithelium are different from classical epithelial Na+ channels.
Topics: 1-Methyl-3-isobutylxanthine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Electrophysiology; Humans; Kinetics; Nasal Mucosa; ortho-Aminobenzoates; Quaternary Ammonium Compounds; Reference Values; Sodium Channels | 1997 |
In vivo activation of CFTR-dependent chloride transport in murine airway epithelium by CNP.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chlorides; Colforsin; Cyclic GMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Mice; Mice, Knockout; Mice, Mutant Strains; Models, Biological; Nasal Mucosa; Natriuretic Peptide, C-Type; Nitroprusside; ortho-Aminobenzoates; Proteins; Trachea | 1997 |
Chloride channel and chloride conductance regulator domains of CFTR, the cystic fibrosis transmembrane conductance regulator.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Base Sequence; Bronchi; Cells, Cultured; Chloride Channels; Chlorides; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; DNA, Complementary; Epithelial Cells; Female; Humans; Membrane Potentials; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Oocytes; Patch-Clamp Techniques; Point Mutation; Protein Conformation; Recombinant Proteins; Sequence Deletion; Transcription, Genetic; Transfection; Xenopus laevis | 1998 |
Exocytosis is not involved in activation of Cl- secretion via CFTR in Calu-3 airway epithelial cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetazolamide; Amiloride; Cell Membrane; Chloride Channels; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Exocytosis; Humans; Lung; Microvilli; Nitrobenzoates; ortho-Aminobenzoates; Respiratory System | 1998 |
Genomic cloning, molecular characterization, and functional analysis of human CLCA1, the first human member of the family of Ca2+-activated Cl- channel proteins.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amino Acid Sequence; Binding Sites; Calcium; Cell Line; Chloride Channels; Chromosome Mapping; Chromosomes, Human, Pair 1; Cloning, Molecular; Cystic Fibrosis; Dithiothreitol; Electrophysiology; Humans; In Situ Hybridization; Intestinal Mucosa; Molecular Sequence Data; Niflumic Acid; Patch-Clamp Techniques; Protein Biosynthesis; Protein Processing, Post-Translational; RNA, Messenger; Sequence Alignment; Sequence Analysis, DNA; Transcription Factors; Transfection | 1998 |
Minor role of Cl- secretion in non-cystic fibrosis and cystic fibrosis human nasal epithelium.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Amiloride; Calcium Channel Blockers; Cells, Cultured; Chloride Channels; Chlorides; Cyclic AMP; Cystic Fibrosis; Humans; Membrane Potentials; Nasal Mucosa; Nitrobenzoates; ortho-Aminobenzoates; Reference Values; Sodium; Sodium Channels | 1999 |
Nitric oxide inhibits whole-cell current in cystic fibrosis pancreatic epithelial cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Calcium Channel Blockers; Cell Line; Charybdotoxin; Cyclic AMP; Cyclic GMP; Cystic Fibrosis; Diltiazem; Enzyme Inhibitors; Epithelial Cells; Glutathione; Humans; Membrane Potentials; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Oxadiazoles; Pancreas; Patch-Clamp Techniques; Penicillamine; Quinoxalines; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione | 1999 |
Effects of cystic fibrosis and congenital bilateral absence of the vas deferens-associated mutations on cystic fibrosis transmembrane conductance regulator-mediated regulation of separate channels.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amino Acid Substitution; Binding Sites; Cell Line; Chloride Channels; Chlorides; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Glyburide; Glycosylation; Humans; Male; Molecular Weight; Mutation; Mutation, Missense; Phenotype; Recombinant Proteins; Vas Deferens | 2000 |
Residual chloride secretion in intestinal tissue of deltaF508 homozygous twins and siblings with cystic fibrosis. The European CF Twin and Sibling Study Consortium.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adolescent; Adult; Child; Child, Preschool; Chlorides; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Diseases in Twins; Electrophysiology; Female; Genotype; Homozygote; Humans; Male; Mutation; Rectum; Reference Values; Twins, Dizygotic; Twins, Monozygotic | 2000 |
Altered intracellular pH regulation in neutrophils from patients with cystic fibrosis.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acids; Adolescent; Adult; Alkalies; Bronchiectasis; Bronchoalveolar Lavage Fluid; Chlorides; Cystic Fibrosis; Female; Humans; Hydrogen; Hydrogen-Ion Concentration; Intracellular Membranes; Male; Monocytes; Neutrophils; Protons; Reference Values; Zinc Compounds | 2000 |
CFTR induces the expression of DRA along with Cl(-)/HCO(3)(-) exchange activity in tracheal epithelial cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Antiporters; Carrier Proteins; Cell Line; Chloride-Bicarbonate Antiporters; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Humans; Membrane Proteins; Reference Values; RNA, Messenger; Sulfate Transporters; Trachea; Transfection; Up-Regulation | 2000 |
Extracellular UTP stimulates electrogenic bicarbonate secretion across CFTR knockout gallbladder epithelium.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Age Factors; Animals; Bicarbonates; Biological Transport; Calcium; Chlorides; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Electrophysiology; Epithelial Cells; Gallbladder; Hydrogen-Ion Concentration; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Stimulation, Chemical; Uridine Triphosphate | 2000 |
Permeabilization via the P2X7 purinoreceptor reveals the presence of a Ca2+-activated Cl- conductance in the apical membrane of murine tracheal epithelial cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Bromine; Calcium; Calcium Channel Blockers; Calixarenes; Cell Line; Cell Membrane; Chelating Agents; Chlorides; Cystic Fibrosis; DNA, Complementary; Electrophysiology; Epithelium; Gluconates; Glyburide; Hypoglycemic Agents; Iodine; Ions; Mice; Niflumic Acid; Nitrobenzoates; ortho-Aminobenzoates; Phenols; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Tamoxifen; Time Factors; Trachea; Uridine Triphosphate | 2000 |
Examining basal chloride transport using the nasal potential difference response in a murine model.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Female; Humans; Ion Transport; Membrane Potentials; Mice; Mice, Inbred Strains; Nasal Mucosa; Thionucleotides | 2001 |
CFTR and lysozyme secretion in human airway epithelial cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Biological Transport; Cell Line; Chlorides; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Enzyme Inhibitors; Humans; Muramidase; Nitric Oxide Donors; Oligonucleotides, Antisense; Respiratory Mucosa; S-Nitrosoglutathione; Thapsigargin | 2001 |
Regulation of Cl- channels in normal and cystic fibrosis airway epithelial cells by extracellular ATP.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Cells, Cultured; Chloride Channels; Chlorides; Cystic Fibrosis; Electric Conductivity; Epithelium; Humans; In Vitro Techniques; Ion Channel Gating; Ion Channels; Membrane Potentials; Membrane Proteins; Respiratory System | 1992 |
cAMP-stimulated ion currents in Xenopus oocytes expressing CFTR cRNA.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Alkaline Phosphatase; Animals; Calcium; Cells, Cultured; Chlorides; Cloning, Molecular; Colforsin; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Humans; Membrane Potentials; Membrane Proteins; Oocytes; RNA; Transcription, Genetic; Xenopus laevis | 1992 |
Small linear chloride channels are endogenous to nonepithelial cells.
Topics: 3T3 Cells; 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Chloride Channels; CHO Cells; Cricetinae; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Epithelial Cells; Epithelium; Female; Fibroblasts; Membrane Proteins; Mice; Ovary | 1992 |
Studies on human porin. III. Does the voltage-dependent anion channel "Porin 31HL" form part of the chloride channel complex, which is observed in different cells and thought to be affected in cystic fibrosis?
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; B-Lymphocytes; Bacterial Outer Membrane Proteins; Biological Transport, Active; Cell Line; Chloride Channels; Chlorides; Cystic Fibrosis; Humans; Ion Channels; Lipid Bilayers; Membrane Potentials; Membrane Proteins; Porins | 1990 |
The reserpine-treated rat as an experimental animal model for cystic fibrosis: abnormal Cl transport in pancreatic acinar cells.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetylcholine; Amiloride; Animals; Biological Transport; Ceruletide; Chlorides; Colforsin; Cystic Fibrosis; Disease Models, Animal; Furosemide; Kinetics; Male; Pancreas; Rats; Rats, Inbred Strains; Reserpine; Vasoactive Intestinal Peptide | 1988 |
Kinetic analysis of chloride efflux from normal and cystic fibrosis fibroblasts.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Cell Membrane Permeability; Chlorides; Cold Temperature; Cystic Fibrosis; Fibroblasts; Humans; Kinetics; Mathematics; Skin | 1986 |