4,4',6-trimethylangelicin has been researched along with Cystic Fibrosis in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bianchi, N; Borgatti, M; Chilin, A; dall'Acqua, F; Gambari, R; Guiotto, A; Lampronti, I; Mancini, I; Marzaro, G; Piccagli, L | 1 |
| Abbattiscianni, AC; Bezzerri, V; Cabrini, G; Casavola, V; Debellis, L; Favia, M; Gambari, R; Guerra, L; Laselva, O; Mancini, MT; Reshkin, SJ | 1 |
| Bartoszewski, R; Collawn, JF; Fu, L; Matalon, S | 1 |
| Atlante, A; Bobba, A; Casavola, V; Favia, M; Guerra, L; Reshkin, SJ | 1 |
| Bear, CE; Casavola, V; Laselva, O; Molinski, S | 1 |
1 review(s) available for 4,4',6-trimethylangelicin and Cystic Fibrosis
| Article | Year |
|---|---|
Rescuing ΔF508 CFTR with trimethylangelicin, a dual-acting corrector and potentiator.
Topics: Amino Acid Sequence; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Furocoumarins; Humans; Protein Folding; Protein Stability; Sequence Deletion | 2014 |
4 other study(ies) available for 4,4',6-trimethylangelicin and Cystic Fibrosis
| Article | Year |
|---|---|
Development of a novel furocoumarin derivative inhibiting NF-κB dependent biological functions: design, synthesis and biological effects.
Topics: Cell Line; Cystic Fibrosis; DNA; Drug Design; Furocoumarins; Gene Expression Regulation; Humans; Interleukin-8; Models, Molecular; NF-kappa B; Protein Binding; RNA, Messenger; Tumor Necrosis Factor-alpha | 2011 |
Trimethylangelicin promotes the functional rescue of mutant F508del CFTR protein in cystic fibrosis airway cells.
Topics: Animals; Cell Line; Cell Membrane; Chlorides; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furocoumarins; HEK293 Cells; Humans; Lung; Protein Transport; Rats | 2014 |
Characterization of mitochondrial function in cells with impaired cystic fibrosis transmembrane conductance regulator (CFTR) function.
Topics: Aminopyridines; Benzodioxoles; Cells, Cultured; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Energy Metabolism; Furocoumarins; Humans; Mitochondrial Diseases; Mutation; Respiratory System | 2016 |
The investigational Cystic Fibrosis drug Trimethylangelicin directly modulates CFTR by stabilizing the first membrane-spanning domain.
Topics: Aminopyridines; Benzodioxoles; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Furocoumarins; HEK293 Cells; Humans; Molecular Structure; Protein Domains | 2016 |