4--methylene-5-8-10-trideazaaminopterin and Lymphoma--Non-Hodgkin

This is the annual perspective paper on the discontinued drugs in the field of pulmonary disease allergy, rheumatology, and dermatology. It is part of series of papers discussing drugs dropped from clinical development in the previous year and presented according to therapeutic indication. Specifically, this paper presents the four rheumatology and dermatology, four pulmonary and three allergy drugs discontinued in 2010. Information for this perspective was derived from a search of the Pharmaprojects database for drugs discontinued after reaching Phase I - III clinical trials.

Topics: Aminopterin; Anti-Allergic Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antipruritics; Antirheumatic Agents; Bronchodilator Agents; Drugs, Investigational; Humans; I-kappa B Kinase; Immunologic Factors; Lymphoma, Non-Hodgkin