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4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and Pregnancy

4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone has been researched along with Pregnancy in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19909 (34.62)18.7374
1990's9 (34.62)18.2507
2000's6 (23.08)29.6817
2010's2 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ahmed, MS; Fokina, VM; Hankins, GDV; Nanovskaya, T; Oncken, C; Patrikeeva, SL1
Benowitz, NL; Hoh, E; Hovell, MF; Jacob, P; Khan, AM; Matt, GE; Northrup, TF; Stotts, AL1
Al-Wadei, HA; Schuller, HM1
Al-Wadei, HA; Al-Wadei, MH; Schuller, HM1
Castonguay, A; Miller, MS; Schuller, HM; Walker, K; Weddle, DL; Zhang, L1
Florek, E; Kornacka, MK; Lechowicz, W; Piekoszewski, W; Szymańska, A1
Castonguay, A; Hecht, SS; Tjälve, H1
Castonguay, A; Hecht, SS; Tjälve, H; Trushin, N1
Castonguay, A; Jorquera, R; Lu, X; Riechert, A; Schüller, HM1
Amin, S; Anderson, LM; Beebe, LE; Kim, YE; Kovatch, RM; Riggs, CW1
Castonguay, A; Jorquera, R; Reichert, A; Schüller, HM1
Amin, S; Anderson, LM; Desai, D; Kasprzak, KS; Sipowicz, MA1
Wise, J1
Kim, PM; Wells, PG; Winn, LM1
Carmella, SG; Chen, M; Hecht, SS; Lackmann, GM; Salzberger, U; Töllner, U1
Castonguay, A; Miller, MS; Schuller, HM; Thomas, PE; Weddle, DL; Zhang, L; Zheng, B1
Atalla, A; Maser, E1
Castonguay, A; Jorquera, R; Schuller, HM1
Castonguay, A; Correa, E; Joshi, PA; Schüller, HM1
Alaoui-Jamali, MA; Castonguay, A; Rossignol, G; Schuller, HM2
Amin, S; Anderson, LM; Dixon, DE; Dove, LF; Hecht, SS; Hoffmann, D; Kovatch, RM; Rice, JM1
Alaoui-Jamali, MA; Castonguay, A; Schuller, HM1
Preston-Martin, S1
Adams, JD; Choi, CI; LaVoie, EJ; Reinhardt, J; Stern, SL1

Reviews

1 review(s) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and Pregnancy

ArticleYear
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
    IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, 1985, Volume: 37

    Topics: Abnormalities, Drug-Induced; Animals; Biotransformation; Carcinogens; Chemical Phenomena; Chemistry; Cricetinae; Female; Humans; Male; Mesocricetus; Mice; Mice, Inbred C57BL; Mutagenicity Tests; Neoplasms, Experimental; Nicotiana; Nitrosamines; Plants, Toxic; Pregnancy; Rats; Rats, Inbred F344; Salmonella typhimurium; Tissue Distribution

1985

Other Studies

25 other study(ies) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and Pregnancy

ArticleYear
The Role of Placental Carbonyl Reducing Enzymes in Biotransformation of Bupropion and 4-methylnitrosamino-1-(3-pyridyl)-1-butanone.
    Drug metabolism letters, 2017, 11-17, Volume: 11, Issue:1

    Topics: Antidepressive Agents; Biotransformation; Bupropion; Cigarette Smoking; Female; Humans; Microsomes; Nitrosamines; Placenta; Pregnancy; Subcellular Fractions; Trophoblasts

2017
Thirdhand smoke contamination in hospital settings: assessing exposure risk for vulnerable paediatric patients.
    Tobacco control, 2016, Volume: 25, Issue:6

    Topics: Carcinogens; Cotinine; Environmental Exposure; Environmental Monitoring; Female; Humans; Infant, Newborn; Intensive Care Units, Neonatal; Nicotine; Nitrosamines; Pregnancy; Tobacco Smoke Pollution

2016
Nicotinic receptor-associated modulation of stimulatory and inhibitory neurotransmitters in NNK-induced adenocarcinoma of the lungs and pancreas.
    The Journal of pathology, 2009, Volume: 218, Issue:4

    Topics: Adenocarcinoma; Animals; Blotting, Western; Carcinoma, Pancreatic Ductal; Cricetinae; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Epinephrine; Female; gamma-Aminobutyric Acid; Lung Neoplasms; Male; Mesocricetus; Models, Animal; Neurotransmitter Agents; Nitrosamines; Norepinephrine; Pancreatic Neoplasms; Pregnancy; Receptors, Nicotinic; Signal Transduction; Smoking

2009
Prevention of pancreatic cancer by the beta-blocker propranolol.
    Anti-cancer drugs, 2009, Volume: 20, Issue:6

    Topics: Adrenergic beta-Antagonists; alpha7 Nicotinic Acetylcholine Receptor; Animals; Anticarcinogenic Agents; Carcinoma, Pancreatic Ductal; Cricetinae; Cyclic AMP; Ethanol; Female; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Pancreatitis; Pregnancy; Prenatal Exposure Delayed Effects; Propranolol; Receptors, Adrenergic, beta; Receptors, Nicotinic

2009
The cyclooxygenase inhibitor ibuprofen and the FLAP inhibitor MK886 inhibit pancreatic carcinogenesis induced in hamsters by transplacental exposure to ethanol and the tobacco carcinogen NNK.
    Journal of cancer research and clinical oncology, 2002, Volume: 128, Issue:10

    Topics: Adenocarcinoma; Animals; Arachidonic Acid; Cricetinae; Cyclooxygenase Inhibitors; DNA Primers; Ethanol; Female; Genes, p53; Genes, ras; Ibuprofen; Indoles; Lipoxygenase Inhibitors; Male; Maternal-Fetal Exchange; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Pregnancy

2002
[Determination of 4-(methylnirosamino) -4-(3-pyridyl)-1-butanol (NNA) in urine of pregnant women by means of LC/MS/MS].
    Przeglad lekarski, 2006, Volume: 63, Issue:10

    Topics: Biomarkers; Environmental Monitoring; Female; Humans; Maternal Exposure; Maternal-Fetal Exchange; Nitrosamines; Pregnancy; Pregnancy Complications; Smoking; Surveys and Questionnaires; Tobacco Smoke Pollution; Tobacco Use Disorder

2006
Fate of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in pregnant and newborn C57BL mice.
    IARC scientific publications, 1984, Issue:57

    Topics: Animals; Animals, Newborn; Autoradiography; Carcinogens; Female; Fetus; Mice; Mice, Inbred C57BL; Nicotiana; Nitrosamines; Plants, Toxic; Pregnancy; Pregnancy, Animal; Tissue Distribution

1984
Perinatal metabolism of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in C57BL mice.
    Journal of the National Cancer Institute, 1984, Volume: 72, Issue:5

    Topics: Animals; Autoradiography; Carbon Radioisotopes; Carcinogens; Chromatography, High Pressure Liquid; Female; Fetus; In Vitro Techniques; Liver; Lung; Mice; Mice, Inbred C57BL; Nasal Mucosa; Nitrosamines; Pregnancy; Scintillation Counting; Tissue Distribution

1984
Transplacental carcinogenicity of low doses of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone administered subcutaneously or intratracheally to hamsters.
    Journal of cancer research and clinical oncology, 1994, Volume: 120, Issue:4

    Topics: Animals; Carcinogens; Cricetinae; Dose-Response Relationship, Drug; Drug Administration Routes; Female; Injections, Subcutaneous; Male; Maternal-Fetal Exchange; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Pregnancy; Prenatal Exposure Delayed Effects; Trachea

1994
Comparison of transplacental and neonatal initiation of mouse lung and liver tumors by N-nitrosodimethylamine (NDMA) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and promotability by a polychlorinated biphenyls mixture (Aroclor 1254).
    Carcinogenesis, 1993, Volume: 14, Issue:8

    Topics: Animals; Animals, Newborn; Aroclors; Carcinogens; Chlorodiphenyl (54% Chlorine); Cocarcinogenesis; Dimethylnitrosamine; Female; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Maternal-Fetal Exchange; Mice; Nitrosamines; Pregnancy; Time Factors

1993
Transplacental induction of pancreas tumors in hamsters by ethanol and the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Cancer research, 1993, Jun-01, Volume: 53, Issue:11

    Topics: Animals; Cricetinae; Drug Synergism; Ethanol; Female; Male; Maternal-Fetal Exchange; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms; Pregnancy; Sex Factors

1993
Oxidative DNA damage in tissues of pregnant female mice and fetuses caused by the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
    Cancer letters, 1997, Jul-15, Volume: 117, Issue:1

    Topics: Animals; DNA Damage; Female; Maternal-Fetal Exchange; Mice; Nicotiana; Nitrosamines; Oxidation-Reduction; Plants, Toxic; Pregnancy

1997
Carcinogen in tobacco smoke can be passed to fetus.
    BMJ (Clinical research ed.), 1998, Aug-29, Volume: 317, Issue:7158

    Topics: Carcinogens; Female; Humans; Maternal-Fetal Exchange; Nitrosamines; Pregnancy; Pregnancy Complications; Smoking

1998
Investigation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone for in vivo and iIn vitro murine embryopathy and embryonic ras mutations.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Carcinogens; Embryo, Mammalian; Female; Fetus; Genes, ras; Mice; Mutation; Nicotiana; Nitrosamines; Organ Culture Techniques; Phenobarbital; Plants, Toxic; Pregnancy

1998
Metabolites of a tobacco-specific carcinogen in urine from newborns.
    Journal of the National Cancer Institute, 1999, Mar-03, Volume: 91, Issue:5

    Topics: Adult; Carcinogens; Cotinine; Female; Gas Chromatography-Mass Spectrometry; Glucuronates; Humans; Infant, Newborn; Nicotine; Nitrosamines; Pregnancy; Prenatal Exposure Delayed Effects; Smoking

1999
Low levels of expression of cytochromes P-450 in normal and cancerous fetal pancreatic tissues of hamsters treated with NNK and/or ethanol.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 56, Issue:2

    Topics: Animals; Blotting, Western; Carcinogens; Cricetinae; Cytochrome P-450 Enzyme System; DNA Adducts; Ethanol; Female; Fetal Diseases; Liver; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms; Pregnancy

2000
Characterization of enzymes participating in carbonyl reduction of 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in human placenta.
    Chemico-biological interactions, 2001, Jan-30, Volume: 130-132, Issue:1-3

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Animals; Base Sequence; Cytosol; DNA Primers; Female; Gene Expression; Humans; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Mice; Microsomes; Nitrosamines; Oxidation-Reduction; Placenta; Pregnancy; RNA, Messenger

2001
Placental transfer of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone instilled intratracheally in Syrian golden hamsters.
    Cancer research, 1992, Jun-15, Volume: 52, Issue:12

    Topics: Animals; Carcinogens; Cricetinae; Female; Maternal-Fetal Exchange; Mesocricetus; Nitrosamines; Pregnancy; Time Factors; Tissue Distribution; Trachea

1992
The tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone is an active transplacental carcinogen in Syrian golden hamsters.
    Cancer research, 1990, Jun-01, Volume: 50, Issue:11

    Topics: Animals; Cricetinae; Female; Injections, Subcutaneous; Litter Size; Male; Maternal-Fetal Exchange; Mesocricetus; Nicotiana; Nitrosamines; Plants, Toxic; Pregnancy; Respiratory Tract Neoplasms; Sex Factors

1990
Transplacental genotoxicity of a tobacco-specific N-nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, in Syrian golden hamster.
    Mutation research, 1989, Volume: 223, Issue:1

    Topics: Animals; Cricetinae; Dose-Response Relationship, Drug; Erythrocytes; Female; Liver; Maternal-Fetal Exchange; Mesocricetus; Micronucleus Tests; Mutagens; Nicotiana; Nitrosamines; Plants, Toxic; Pregnancy

1989
Evaluation of the transplacental tumorigenicity of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mice.
    Cancer research, 1989, Jul-15, Volume: 49, Issue:14

    Topics: Animals; Carcinogens; Female; Fetus; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Neoplasms, Experimental; Nicotiana; Nitrosamines; Placenta; Plants, Toxic; Pregnancy

1989
Metabolism and DNA damage induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in fetal tissues of the Syrian golden hamster.
    Cancer research, 1989, Oct-15, Volume: 49, Issue:20

    Topics: Alkylating Agents; Animals; Chromosome Aberrations; Cricetinae; Culture Techniques; DNA Damage; Female; Fetus; Guanine; Lung; Maternal-Fetal Exchange; Methylation; Nitrosamines; Placenta; Pregnancy; Trachea

1989
In vitro genotoxicity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone activated by hamster maternal and fetal tissues.
    Carcinogenesis, 1988, Volume: 9, Issue:12

    Topics: Animals; Biotransformation; Carcinogens; Chromosome Aberrations; Cricetinae; Female; Fetus; Liver; Lung; Mesocricetus; Mutagens; Nicotiana; Nitrosamines; Plants, Toxic; Pregnancy

1988
N-nitroso compounds as a cause of human cancer.
    IARC scientific publications, 1987, Issue:84

    Topics: Adult; China; Epidemiologic Methods; Esophageal Neoplasms; Female; Humans; Nasopharyngeal Neoplasms; Neoplasms; Nicotiana; Nitrosamines; Nitroso Compounds; Plants, Toxic; Pregnancy; Prenatal Exposure Delayed Effects; Risk Factors; Tobacco Smoke Pollution; Tobacco, Smokeless

1987
Transfer of the tobacco-specific carcinogens N'-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and benzo[a]pyrene into the milk of lactating rats.
    Carcinogenesis, 1987, Volume: 8, Issue:3

    Topics: Animals; Benzo(a)pyrene; Carbon Radioisotopes; Carcinogens; Female; Lactation; Milk; Nicotiana; Nitrosamines; Plants, Toxic; Pregnancy; Rats; Rats, Inbred Strains; Smoking

1987