Compounds > 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone
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4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and Precancerous Conditions

4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone has been researched along with Precancerous Conditions in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's6 (66.67)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brunnemann, KD; Enzmann, HG; Iatropoulos, MJ; Kaestner, B; Williams, GM1
Abe, M; Endo, Y; Igarashi, M; Miyajima, N; Nakae, D; Sugano, S; Sugaya, K; Watanabe, M; Yoshida, M1
Chen, GG; Hsin, MK; Kong, AW; Li, MY; Ma, LT; Underwood, MJ; Yip, JH; Yuan, H1
Kim, Y; Liu, C; Liu, XS; Russell, RM; Smith, DE; Wang, XD1
Aggarwal, BB; Deo, SV; Gupta, SD; Kaur, J; Ralhan, R; Rohatgi, N; Sawhney, M; Sethi, G; Shishodia, S; Shukla, NK1
Chen, HL; Lai, BT; Liu, MQ; Xia, D; Yang, F; Ye, B; Zhang, YX1
Choudhary, S; Siriwardhana, N; Wang, HC1
Baylin, SB; Belinsky, SA; Gabrielson, E; Herman, JG; Michels, R; Nikula, KJ; Palmisano, WA; Saccomanno, G1
Belinsky, SA; March, TH; Wardlaw, SA1

Other Studies

9 other study(ies) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and Precancerous Conditions

ArticleYear
Dose-dependent induction of preneoplastic lesions by the tobacco-specific nitrosamine carcinogen NNK in the in ovo carcinogenicity assessment (IOCA) assay.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2014, Volume: 66, Issue:1

    Topics: Animals; Carcinogenicity Tests; Carcinogens; Dose-Response Relationship, Drug; Female; Hepatocytes; Nicotiana; Nitrosamines; Ovum; Precancerous Conditions; Turkeys

2014
Enhancement of lung carcinogenesis initiated with 4-(N-hydroxymethylnitrosamino)-1-(3-pyridyl)-1-butanone by Ogg1 gene deficiency in female, but not male, mice.
    The Journal of toxicological sciences, 2009, Volume: 34, Issue:2

    Topics: Adenocarcinoma; Adenoma; Administration, Oral; Animals; Antioxidants; Carcinogens; DNA Glycosylases; Drug Antagonism; Female; Genes, erbB-1; Genes, ras; Humans; Infusions, Subcutaneous; Lung; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Nitrosamines; Precancerous Conditions; Sex Factors

2009
Roles of peroxisome proliferator-activated receptor-alpha and -gamma in the development of non-small cell lung cancer.
    American journal of respiratory cell and molecular biology, 2010, Volume: 43, Issue:6

    Topics: Animals; Carcinoma, Non-Small-Cell Lung; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Humans; Hydroxyeicosatetraenoic Acids; Ligands; Linoleic Acids; Lipid Metabolism; Lung Neoplasms; Male; Mice; Nitrosamines; Pioglitazone; PPAR alpha; PPAR gamma; Precancerous Conditions; Retinoid X Receptor alpha; Signal Transduction; Thiazolidinediones; Transcription, Genetic

2010
Induction of pulmonary neoplasia in the smoke-exposed ferret by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK): a model for human lung cancer.
    Cancer letters, 2006, Mar-28, Volume: 234, Issue:2

    Topics: Adenocarcinoma; Animals; Carcinogens; Carcinoma, Squamous Cell; Disease Models, Animal; Ferrets; Humans; Immunohistochemistry; Lung Neoplasms; Male; Nitrosamines; Precancerous Conditions; Smoking

2006
Expression of NF-kappaB parallels COX-2 expression in oral precancer and cancer: association with smokeless tobacco.
    International journal of cancer, 2007, Jun-15, Volume: 120, Issue:12

    Topics: Adult; Aged; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Chi-Square Distribution; Cyclooxygenase 2; Cytoplasm; Dose-Response Relationship, Drug; Female; Humans; Immunohistochemistry; Male; Membrane Proteins; Microscopy, Confocal; Middle Aged; Mouth Neoplasms; NF-kappa B; Nitrosamines; Oligonucleotides; Plant Extracts; Precancerous Conditions; Protein Binding; Time Factors; Tobacco, Smokeless

2007
Induction of lung lesions in Wistar rats by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and its inhibition by aspirin and phenethyl isothiocyanate.
    BMC cancer, 2007, May-29, Volume: 7

    Topics: Animals; Anticarcinogenic Agents; Aspirin; Carcinogens; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Female; Immunohistochemistry; Isothiocyanates; Lung Neoplasms; Nicotiana; Nitrosamines; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar

2007
Precancerous model of human breast epithelial cells induced by NNK for prevention.
    Breast cancer research and treatment, 2008, Volume: 109, Issue:3

    Topics: Breast Neoplasms; Carcinogens; Cell Line; Cell Survival; Female; Gene Expression Profiling; Grape Seed Extract; Growth Substances; Humans; Nitrosamines; Plant Extracts; Precancerous Conditions; Proanthocyanidins

2008
Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Sep-29, Volume: 95, Issue:20

    Topics: Adenoma; Animals; Biomarkers, Tumor; Carcinogens; Carcinoma in Situ; Carcinoma, Squamous Cell; DNA Methylation; DNA, Neoplasm; Genes, p16; Humans; Hyperplasia; Lung Neoplasms; Metaplasia; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred F344; Sputum

1998
Cyclooxygenase-2 expression is abundant in alveolar type II cells in lung cancer-sensitive mouse strains and in premalignant lesions.
    Carcinogenesis, 2000, Volume: 21, Issue:7

    Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinogens; Cell Division; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Susceptibility; Humans; Isoenzymes; Lung Neoplasms; Membrane Proteins; Mice; Mice, Inbred A; Mice, Inbred C3H; Mice, Nude; Neoplasm Transplantation; Nitrosamines; Precancerous Conditions; Proline; Prostaglandin-Endoperoxide Synthases; Pulmonary Alveoli; Pyrazoles; RNA, Messenger; Sulfonamides; Thiocarbamates; Transcription, Genetic; Transplantation, Heterologous; Tumor Cells, Cultured

2000