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4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and Mouth Neoplasms

4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone has been researched along with Mouth Neoplasms in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19905 (26.32)18.7374
1990's6 (31.58)18.2507
2000's3 (15.79)29.6817
2010's4 (21.05)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Chang, HJ; Chang, JY; Chou, ST; Hsiao, JR; Hsu, YM; Kuo, CC; Peng, HY; Shiah, SG; Wu, GH1
Chen, CT; Ko, HT; Lee, CH; Liu, TY; Tsou, HH; Wang, HT; Wang, TW1
Chen, SF; Chu, YH; Jao, SW; Lee, TY; Lin, YS; Liu, CL; Liu, TY; Nieh, S; Tseng, YH; Yang, CY1
Carmella, SG; Hecht, SS; Stepanov, I1
Kathman, S; Naufal, Z; Wilson, C1
Bernard, HU; Grando, SA; Kalantari-Dehaghi, M1
Aggarwal, BB; Deo, SV; Gupta, SD; Kaur, J; Ralhan, R; Rohatgi, N; Sawhney, M; Sethi, G; Shishodia, S; Shukla, NK1
Arredondo, J; Chernyavsky, AI; Grando, SA1
Bhide, SV; Nagarajrao, D; Nair, J; Shah, AS1
Adams, JD; Hoffmann, D1
Baek, JH; Cherrick, HM; Kim, MS; Park, NH; Shin, KH1
Djordjevic, MV; Hoffmann, D1
Lazarus, P; Park, JY; Ren, Q; Richie, JP; Schantz, SP; Sheikh, SN; Stern, JC1
Hecht, SS; Hoffmann, D1
Hoffmann, D; Prokopczyk, B; Rivenson, A1
Bowman, D; Davis, WJ; Heiblum, R; King, PG; Murphy, SE; Stoner, GD1
Bhide, SV; Gijare, PS; Rao, KV1
Amonkar, AJ; Bhide, SV; Lalitha, VS; Padma, PR1
Adams, JD; Braley, J; DiBello, J; Hecht, SS; Hoffmann, D; Rivenson, A1

Reviews

1 review(s) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and Mouth Neoplasms

ArticleYear
Chemical composition and carcinogenicity of smokeless tobacco.
    Advances in dental research, 1997, Volume: 11, Issue:3

    Topics: Animals; Biotransformation; Carcinogenicity Tests; Carcinogens; Cricetinae; Humans; Mouth Neoplasms; Nitrosamines; Plants, Toxic; Rats; Tobacco, Smokeless; United States

1997

Other Studies

18 other study(ies) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and Mouth Neoplasms

ArticleYear
MiR-30a and miR-379 modulate retinoic acid pathway by targeting DNA methyltransferase 3B in oral cancer.
    Journal of biomedical science, 2020, Apr-02, Volume: 27, Issue:1

    Topics: Alcohol Oxidoreductases; Aldehyde Dehydrogenase 1 Family; Arecoline; Carcinogenesis; Carcinoma, Squamous Cell; Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3B; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Metabolic Networks and Pathways; MicroRNAs; Mitochondrial Proteins; Mouth Neoplasms; Nitrosamines; Retinal Dehydrogenase; Tretinoin

2020
Betel quid containing safrole enhances metabolic activation of tobacco specific 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
    Environmental pollution (Barking, Essex : 1987), 2019, Volume: 251

    Topics: Activation, Metabolic; Animals; Carcinoma, Squamous Cell; Cricetinae; Cytochrome P-450 CYP2A6; Female; Humans; Liver; Mouth Neoplasms; Nicotiana; Nitrosamines; Safrole; Taiwan; Tobacco Use

2019
Regulation of tumor progression via the Snail-RKIP signaling pathway by nicotine exposure in head and neck squamous cell carcinoma.
    Head & neck, 2015, Volume: 37, Issue:12

    Topics: Aldehyde Dehydrogenase 1 Family; alpha7 Nicotinic Acetylcholine Receptor; Apoptosis; Carcinogens; Carcinoma, Squamous Cell; Cell Culture Techniques; Cell Line, Tumor; Cell Movement; Disease Progression; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Head and Neck Neoplasms; Humans; Hypopharyngeal Neoplasms; Isoenzymes; Mouth Neoplasms; Neoplasm Invasiveness; Neoplasm Staging; Neoplastic Stem Cells; Nicotine; Nicotinic Agonists; Nitrosamines; Retinal Dehydrogenase; Signal Transduction; Snail Family Transcription Factors; Tongue Neoplasms; Transcription Factors; Up-Regulation

2015
Exposure and Metabolic Activation Biomarkers of Carcinogenic Tobacco-Specific Nitrosamines.
    Accounts of chemical research, 2016, Jan-19, Volume: 49, Issue:1

    Topics: Activation, Metabolic; Animals; Biomarkers, Tumor; Carcinogens; Humans; Lung Neoplasms; Mouth Neoplasms; Nitrosamines; Rats; Smoking; Tobacco Products

2016
Bayesian derivation of an oral cancer slope factor distribution for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
    Regulatory toxicology and pharmacology : RTP, 2009, Volume: 55, Issue:1

    Topics: Animals; Bayes Theorem; Carcinogenicity Tests; Carcinogens; Decision Support Techniques; Disease Models, Animal; Dose-Response Relationship, Drug; Environmental Exposure; Female; Humans; Lung Neoplasms; Male; Mice; Models, Biological; Monte Carlo Method; Mouth Neoplasms; Neoplasms, Experimental; Nitrosamines; Pancreatic Neoplasms; Rats; Risk Assessment; United States; United States Environmental Protection Agency

2009
Reciprocal effects of NNK and SLURP-1 on oncogene expression in target epithelial cells.
    Life sciences, 2012, Nov-27, Volume: 91, Issue:21-22

    Topics: Antigens, Ly; Bronchi; Carcinogens; Cell Line, Tumor; Cell Transformation, Neoplastic; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mouth; Mouth Neoplasms; Nitrosamines; Urokinase-Type Plasminogen Activator

2012
Expression of NF-kappaB parallels COX-2 expression in oral precancer and cancer: association with smokeless tobacco.
    International journal of cancer, 2007, Jun-15, Volume: 120, Issue:12

    Topics: Adult; Aged; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Chi-Square Distribution; Cyclooxygenase 2; Cytoplasm; Dose-Response Relationship, Drug; Female; Humans; Immunohistochemistry; Male; Membrane Proteins; Microscopy, Confocal; Middle Aged; Mouth Neoplasms; NF-kappa B; Nitrosamines; Oligonucleotides; Plant Extracts; Precancerous Conditions; Protein Binding; Time Factors; Tobacco, Smokeless

2007
Overexpression of SLURP-1 and -2 alleviates the tumorigenic action of tobacco-derived nitrosamine on immortalized oral epithelial cells.
    Biochemical pharmacology, 2007, Oct-15, Volume: 74, Issue:8

    Topics: Adaptor Proteins, Signal Transducing; Antigens, Ly; Carcinogens; Cell Line; GPI-Linked Proteins; Humans; Membrane Glycoproteins; Mouth Neoplasms; Nitrosamines; Urokinase-Type Plasminogen Activator

2007
Epidemiological and experimental studies on tobacco-related oral cancer in India.
    IARC scientific publications, 1984, Issue:57

    Topics: Animals; Carcinogens; Female; Humans; India; Male; Mice; Mice, Inbred Strains; Mouth Neoplasms; Mutagenicity Tests; Mutagens; Nicotiana; Nitrosamines; Pharyngeal Neoplasms; Plants, Toxic; Salmonella typhimurium; Smoking

1984
Carcinogenic tobacco-specific N-nitrosamines in snuff and in the saliva of snuff dippers.
    Cancer research, 1981, Volume: 41, Issue:11 Pt 1

    Topics: Adult; Alkaloids; Denmark; Germany, West; Humans; Male; Middle Aged; Mouth Neoplasms; Nicotiana; Nicotine; Nitrosamines; Plants, Toxic; Pyridines; Saliva; Sweden; Tobacco, Smokeless; United States

1981
HPV-16, tobacco-specific N-nitrosamine, and N-methyl-N'-nitro-N-nitrosoguanidine in oral carcinogenesis.
    Cancer research, 1993, Oct-15, Volume: 53, Issue:20

    Topics: Base Sequence; Carcinogens; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Colonic Neoplasms; DNA Primers; ErbB Receptors; Exons; Genes, myc; Genes, p53; Genes, ras; Humans; Keratinocytes; Male; Methylnitronitrosoguanidine; Molecular Sequence Data; Mouth Neoplasms; Mutagenesis; Nicotiana; Nitrosamines; Oligonucleotides, Antisense; Papillomaviridae; Plants, Toxic; Polymerase Chain Reaction; Transforming Growth Factor alpha

1993
p53, but not p16 mutations in oral squamous cell carcinomas are associated with specific CYP1A1 and GSTM1 polymorphic genotypes and patient tobacco use.
    Carcinogenesis, 1998, Volume: 19, Issue:3

    Topics: Benzo(a)pyrene; Carcinoma, Squamous Cell; Cyclin-Dependent Kinase Inhibitor p16; Cytochrome P-450 CYP1A1; Exons; Genes, p53; Genotype; Glutathione Transferase; Humans; Mouth Neoplasms; Mutation; Nicotiana; Nitrosamines; Plants, Toxic; Polymorphism, Genetic; Smoking

1998
N-nitroso compounds and tobacco-induced cancers in man.
    IARC scientific publications, 1991, Issue:105

    Topics: Carcinogens; Esophageal Neoplasms; Humans; Lung Neoplasms; Mouth Neoplasms; Nitrosamines; Pancreatic Neoplasms; Smoking

1991
A study of betel quid carcinogenesis. IX. Comparative carcinogenicity of 3-(methylnitrosamino)propionitrile and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone upon local application to mouse skin and rat oral mucosa.
    Cancer letters, 1991, Volume: 60, Issue:2

    Topics: Administration, Topical; Animals; Areca; Body Weight; Carcinogens; Esophageal Neoplasms; Female; Humans; Infant, Newborn; Lung Neoplasms; Male; Mice; Mouth Neoplasms; Nitrosamines; Nose Neoplasms; Plants, Medicinal; Rats; Rats, Inbred F344; Skin Neoplasms

1991
Effect of phenethyl isothiocyanate on the metabolism of tobacco-specific nitrosamines by cultured rat oral tissue.
    Carcinogenesis, 1991, Volume: 12, Issue:6

    Topics: Animals; Carcinogens; Culture Techniques; Hydroxylation; Isothiocyanates; Male; Mouth Mucosa; Mouth Neoplasms; Nitrosamines; Plants, Toxic; Rats; Rats, Inbred F344; Thiocyanates; Tobacco, Smokeless

1991
Effects of tobacco-specific nitrosamines and snuff extract on cell proliferation and activities of ornithine decarboxylase and aryl hydrocarbon hydroxylase in mouse tongue primary epithelial cell cultures.
    Journal of cancer research and clinical oncology, 1989, Volume: 115, Issue:6

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Carcinogens; Cell Division; Cells, Cultured; Epithelium; Mice; Mice, Inbred BALB C; Mouth Neoplasms; Nicotiana; Nitrosamines; Ornithine Decarboxylase; Plants, Toxic; Tobacco, Smokeless; Tongue

1989
Carcinogenicity studies on the two tobacco-specific N-nitrosamines, N'-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Carcinogenesis, 1989, Volume: 10, Issue:11

    Topics: Animals; Body Weight; Carcinogens; Cricetinae; Diet; Hydrogen Peroxide; Mesocricetus; Mice; Mice, Inbred Strains; Mouth Neoplasms; Nitrosamines; Survival Analysis; Vitamin A Deficiency

1989
Induction of oral cavity tumors in F344 rats by tobacco-specific nitrosamines and snuff.
    Cancer research, 1986, Volume: 46, Issue:8

    Topics: Animals; Carcinogens; Herpes Simplex; Male; Mouth Neoplasms; Nicotiana; Nitrosamines; Plants, Toxic; Rats; Rats, Inbred F344; Tobacco, Smokeless

1986