Compounds > 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone
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4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and Liver Neoplasms

4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone has been researched along with Liver Neoplasms in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19905 (55.56)18.7374
1990's4 (44.44)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, CB; Hecht, SS; Hoffmann, D; Ohmori, T1
Gonzalez, FJ; Guengerich, FP; Guo, Z; Smith, TJ; Stoner, GD; Yang, CS1
Castonguay, A; Gerson, SL; Liu, L1
Amin, S; Anderson, LM; Hecht, SS; Hoffmann, D; Kovatch, RM; Rice, JM1
Anderson, MW; Belinsky, SA; Foley, JF; Maronpot, RR; White, CM1
Amin, SG; Chung, FL; Conran, PB; Hecht, SS; Mandal, S; Morse, MA; Stoner, GD; Wang, CX1
Amin, SG; Chung, FL; Hecht, SS; Morse, MA; Wang, CX1
Castonguay, A; Hecht, SS; Lin, D; Rivenson, A1
Castonguay, A; Hecht, SS; Rivenson, A; Trushin, N1

Other Studies

9 other study(ies) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and Liver Neoplasms

ArticleYear
Comparative carcinogenicity in F344 rats of the tobacco-specific nitrosamines, N'-nitrosonornicotine and 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone.
    Cancer research, 1980, Volume: 40, Issue:2

    Topics: Animals; Carcinogens; Female; Liver Neoplasms; Lung Neoplasms; Male; Nasal Cavity; Neoplasms, Experimental; Nicotiana; Nicotine; Nitrosamines; Nose Neoplasms; Plants, Toxic; Pyridines; Rats; Rats, Inbred F344

1980
Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human lung and liver microsomes and cytochromes P-450 expressed in hepatoma cells.
    Cancer research, 1992, Apr-01, Volume: 52, Issue:7

    Topics: Antibodies; Biotransformation; Carcinogens; Carcinoma, Hepatocellular; Cell Line; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Kinetics; Liver Neoplasms; Lung; Microsomes; Microsomes, Liver; Models, Theoretical; Nitrosamines; Recombinant Proteins; Tritium

1992
Lack of correlation between DNA methylation and hepatocarcinogenesis in rats and hamsters treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Carcinogenesis, 1992, Volume: 13, Issue:11

    Topics: Animals; Carcinogens; Cells, Cultured; Cricetinae; DNA; Guanine; Liver; Liver Neoplasms; Male; Mesocricetus; Methylation; Methyltransferases; Nitrosamines; O(6)-Methylguanine-DNA Methyltransferase; Rats; Rats, Inbred F344

1992
Tumorigenicity of the tobacco-specific carcinogen 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone in infant mice.
    Cancer letters, 1991, Jul-04, Volume: 58, Issue:3

    Topics: Animals; Animals, Newborn; Carcinogens; Female; Liver Neoplasms; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Nitrosamines

1991
Dose-response relationship between O6-methylguanine formation in Clara cells and induction of pulmonary neoplasia in the rat by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Cancer research, 1990, Jun-15, Volume: 50, Issue:12

    Topics: Animals; Cell Line; DNA; Dose-Response Relationship, Drug; Guanine; Hyperplasia; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Male; Metaplasia; Methylation; Microscopy, Electron; Nitrosamines; Nose Neoplasms; Olfactory Mucosa; Rats; Rats, Inbred F344

1990
Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA adduct formation and tumorigenicity in the lung of F344 rats by dietary phenethyl isothiocyanate.
    Cancer research, 1989, Feb-01, Volume: 49, Issue:3

    Topics: Alkylation; Animals; Biological Assay; Diet; DNA; Isothiocyanates; Liver Neoplasms; Lung Neoplasms; Methylation; Nicotiana; Nitrosamines; Nose Neoplasms; Plants, Toxic; Rats; Rats, Inbred F344; Thiocyanates

1989
Effects of dietary sinigrin or indole-3-carbinol on O6-methylguanine-DNA-transmethylase activity and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA methylation and tumorigenicity in F344 rats.
    Carcinogenesis, 1988, Volume: 9, Issue:10

    Topics: Animals; Carcinogens; Diet; DNA; Glucosinolates; Indoles; Liver Neoplasms; Lung Neoplasms; Male; Methylation; Methyltransferases; Neoplasms, Experimental; Nitrosamines; Nose Neoplasms; O(6)-Methylguanine-DNA Methyltransferase; Pancreatic Neoplasms; Rats; Rats, Inbred F344; Thioglycosides

1988
Effects of alpha-deuterium substitution on the tumorigenicity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in F344 rats.
    Carcinogenesis, 1987, Volume: 8, Issue:2

    Topics: Animals; Biotransformation; Deuterium; DNA Damage; Hydroxylation; Liver Neoplasms; Lung Neoplasms; Neoplasms, Experimental; Nitrosamines; Nose Neoplasms; Rats; Rats, Inbred F344; Structure-Activity Relationship

1987
Comparative tumorigenicity and DNA methylation in F344 rats by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N-nitrosodimethylamine.
    Cancer research, 1986, Volume: 46, Issue:2

    Topics: Animals; Dimethylnitrosamine; DNA, Neoplasm; Guanine; Liver Neoplasms; Lung Neoplasms; Male; Methylation; Neoplasms, Experimental; Nicotiana; Nitrosamines; Nose Neoplasms; Plants, Toxic; Rats

1986