Compounds > 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone
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4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and Invasiveness, Neoplasm

4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone has been researched along with Invasiveness, Neoplasm in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, SF; Chu, YH; Jao, SW; Lee, TY; Lin, YS; Liu, CL; Liu, TY; Nieh, S; Tseng, YH; Yang, CY1
Hung, WC; Hung, YH1
Curran, WJ; Deng, X; Khuri, FR; Owonikoko, TK; Shen, J; Sun, SY; Xu, L1
Deng, X; Xu, L1
Caamano, J; Garcia-Palazzo, I; Harris, CC; Iizasa, T; Klein-Szanto, AJ; Metcalf, R; Momiki, S; Welsh, J1

Other Studies

5 other study(ies) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and Invasiveness, Neoplasm

ArticleYear
Regulation of tumor progression via the Snail-RKIP signaling pathway by nicotine exposure in head and neck squamous cell carcinoma.
    Head & neck, 2015, Volume: 37, Issue:12

    Topics: Aldehyde Dehydrogenase 1 Family; alpha7 Nicotinic Acetylcholine Receptor; Apoptosis; Carcinogens; Carcinoma, Squamous Cell; Cell Culture Techniques; Cell Line, Tumor; Cell Movement; Disease Progression; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Head and Neck Neoplasms; Humans; Hypopharyngeal Neoplasms; Isoenzymes; Mouth Neoplasms; Neoplasm Invasiveness; Neoplasm Staging; Neoplastic Stem Cells; Nicotine; Nicotinic Agonists; Nitrosamines; Retinal Dehydrogenase; Signal Transduction; Snail Family Transcription Factors; Tongue Neoplasms; Transcription Factors; Up-Regulation

2015
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) enhances invasiveness of lung cancer cells by up-regulating contactin-1 via the alpha7 nicotinic acetylcholine receptor/ERK signaling pathway.
    Chemico-biological interactions, 2009, May-15, Volume: 179, Issue:2-3

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Bungarotoxins; Cell Adhesion Molecules, Neuronal; Contactin 1; Contactins; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression Profiling; Humans; Lung Neoplasms; Neoplasm Invasiveness; Nitrosamines; Receptors, Nicotinic; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transcription, Genetic; Tumor Cells, Cultured; Up-Regulation

2009
NNK promotes migration and invasion of lung cancer cells through activation of c-Src/PKCĪ¹/FAK loop.
    Cancer letters, 2012, May-01, Volume: 318, Issue:1

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Blotting, Western; Bungarotoxins; Carcinogens; Cell Adhesion; Cell Movement; Fluorescent Antibody Technique; Focal Adhesion Kinase 1; Humans; Isoenzymes; Lung Neoplasms; Neoplasm Invasiveness; Nitrosamines; Protein Kinase C; Proto-Oncogene Proteins pp60(c-src); Receptors, Nicotinic; RNA, Small Interfering; Tumor Cells, Cultured; Wound Healing

2012
Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induces phosphorylation of mu- and m-calpain in association with increased secretion, cell migration, and invasion.
    The Journal of biological chemistry, 2004, Dec-17, Volume: 279, Issue:51

    Topics: Blotting, Western; Calpain; Carcinogens; Cell Line, Tumor; Cell Movement; Disease Progression; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Flavonoids; Gene Silencing; Genetic Vectors; Humans; Immunoprecipitation; Lung Neoplasms; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Models, Biological; Neoplasm Invasiveness; Neoplasm Metastasis; Nicotiana; Nitrosamines; Phosphorylation; RNA Interference; RNA, Small Interfering; Signal Transduction

2004
A tobacco-specific N-nitrosamine or cigarette smoke condensate causes neoplastic transformation of xenotransplanted human bronchial epithelial cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Aug-01, Volume: 89, Issue:15

    Topics: Animals; Biomarkers, Tumor; Bronchi; Carcinogens; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Chemotaxis; Epithelium; ErbB Receptors; Gelatinases; Humans; Isoenzymes; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Invasiveness; Nitrosamines; Pepsin A; Rats; Smoke; Smoking; Tetradecanoylphorbol Acetate; Trachea; Transforming Growth Factor alpha; Transplantation, Heterologous

1992