4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone has been researched along with Hyperplasia in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (52.94) | 18.2507 |
| 2000's | 5 (29.41) | 29.6817 |
| 2010's | 3 (17.65) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Imaida, K; Inoue, T; Kishi, S; Kuno, T; Nakano, Y; Ninomiya, F; Yamakawa, K; Yokohira, M | 1 |
| Imaida, K; Kinouch, S; Kishi, S; Nakano, Y; Ninomiya, F; Saoo, K; Tanizawa, J; Yamakawa, K; Yokohira, M | 1 |
| Hosokawa, K; Imaida, K; Kuno, T; Matsuda, Y; Saoo, K; Takeuchi, H; Yamakawa, K; Yokohira, M | 1 |
| Linnoila, RI; Naizhen, X; Poulsen, HS; Poulsen, TT | 1 |
| Chen, GG; Hsin, MK; Kong, AW; Li, MY; Ma, LT; Underwood, MJ; Wan, IY; Yuan, H | 1 |
| Bartels, T; Ehrhardt, A; Halter, R; Klocke, R; Paul, D | 1 |
| Belinsky, SA; Devereux, TR; Hutt, JA; Pulling, LC; Vuillemenot, BR | 1 |
| Hosokawa, K; Imaida, K; Matsuda, Y; Saoo, K; Takeuchi, H; Yamakawa, K; Yokohira, M; Zeng, Y | 1 |
| Graham, SA; Linnoila, RI; Oreffo, VI; Sunday, ME; Willett, CG; Witschi, H | 1 |
| Richards, RJ | 1 |
| Chen, YP; Johnson, GK; Squier, CA | 1 |
| Graham, SA; Patidar, K; Sunday, ME; Willett, CG | 1 |
| Baylin, SB; Belinsky, SA; Issa, JP; Nikula, KJ | 1 |
| Bondoc, F; Ding, W; Kim, S; Liao, J; Liu, Z; Seril, DN; Yang, CS; Yang, GY | 1 |
| Baylin, SB; Belinsky, SA; Gabrielson, E; Herman, JG; Michels, R; Nikula, KJ; Palmisano, WA; Saccomanno, G | 1 |
| Anderson, MW; Belinsky, SA; Devereux, TR; Foley, JF; Maronpot, RR | 1 |
| Anderson, MW; Belinsky, SA; Foley, JF; Maronpot, RR; White, CM | 1 |
17 other study(ies) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and Hyperplasia
| Article | Year |
|---|---|
Gender-dependent effects of gonadectomy on lung carcinogenesis by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in female and male A/J mice.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogenesis; Estradiol; Female; Humans; Hyperplasia; Lung; Lung Neoplasms; Male; Mice; Neoplasms, Hormone-Dependent; Nitrosamines; Orchiectomy; Ovariectomy; Sex Characteristics; Testosterone | 2013 |
Napsin A is possibly useful marker to predict the tumorigenic potential of lung bronchiolo-alveolar hyperplasia in F344 rats.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Adenoma; Animals; Aspartic Acid Endopeptidases; Biomarkers, Tumor; Bronchioles; Hyperplasia; Immunohistochemistry; Lung; Lung Neoplasms; Nitrosamines; Prognosis; Pulmonary Alveoli; Rats; Rats, Inbred F344 | 2014 |
Establishment of a bioassay model for lung cancer chemoprevention initiated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in female A/J mice.
Topics: Adenoma; Animals; Anticarcinogenic Agents; Carcinogens; Disease Models, Animal; Drug Screening Assays, Antitumor; Female; Hyperplasia; Injections, Intraperitoneal; Lung Neoplasms; Mice; Mice, Inbred A; Nitrosamines; Time Factors | 2008 |
Acute damage by naphthalene triggers expression of the neuroendocrine marker PGP9.5 in airway epithelial cells.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cyclin-Dependent Kinase Inhibitor p27; Epithelial Cells; Hyperplasia; Lung; Lung Neoplasms; Male; Mice; Naphthalenes; Neurosecretory Systems; Nitrosamines; RNA, Messenger; Ubiquitin Thiolesterase | 2008 |
Pioglitazone prevents smoking carcinogen-induced lung tumor development in mice.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Humans; Hydroxyeicosatetraenoic Acids; Hyperplasia; Ligands; Linoleic Acids; Lung Neoplasms; Mice; Nitrosamines; Pioglitazone; PPAR gamma; Pulmonary Alveoli; Smoking; Thiazolidinediones; Time Factors; Transcription, Genetic | 2012 |
Increased susceptibility to the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in transgenic mice overexpressing c-myc and epidermal growth factor in alveolar type II cells.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Animals; Carcinogens; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Hyperplasia; Intercellular Signaling Peptides and Proteins; Lung; Lung Neoplasms; Mice; Mice, Transgenic; Nitrosamines; Peptides; Proto-Oncogene Proteins c-myc; Pulmonary Surfactant-Associated Protein C; Pulmonary Surfactants | 2003 |
Aberrant promoter hypermethylation of the death-associated protein kinase gene is early and frequent in murine lung tumors induced by cigarette smoke and tobacco carcinogens.
Topics: Animals; Apoptosis Regulatory Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Cell Line, Tumor; CpG Islands; Death-Associated Protein Kinases; DNA Methylation; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Silencing; Hyperplasia; Lung; Lung Neoplasms; Methylene Chloride; Mice; Mice, Inbred A; Nitrosamines; Promoter Regions, Genetic; Smoking; Urethane | 2004 |
Post-initiation chemopreventive effects of dietary bovine lactoferrin on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis in female A/J mice.
Topics: Adenoma; Animals; Body Weight; Caspase 3; Cattle; Dietary Supplements; Female; Hyperplasia; Lactoferrin; Lung; Lung Neoplasms; Mice; Mice, Inbred A; Nitrosamines; Organ Size; Proliferating Cell Nuclear Antigen | 2007 |
Histochemical characterization of non-neuroendocrine tumors and neuroendocrine cell hyperplasia induced in hamster lung by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone with or without hyperoxia.
Topics: Animals; Carcinogens; Cricetinae; Histocytochemistry; Hyperplasia; Immunoenzyme Techniques; Lung Neoplasms; Male; Mesocricetus; Neurosecretory Systems; Nitrosamines; Oxygen | 1995 |
Networks controlling pneumocyte proliferation. Modulation of oncogene and tumor suppressor gene expression in a hamster model of chronic lung injury with varying degrees of pulmonary neuroendocrine cell hyperplasia.
Topics: Animals; Carcinogens; Cell Differentiation; Cell Division; Cricetinae; Diethylnitrosamine; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Genes, myc; Genes, Tumor Suppressor; Hyperplasia; Lung; Neurosecretory Systems; Nitrosamines | 1994 |
Effects of nicotine and tobacco-specific nitrosamines on hamster cheek pouch and gastric mucosa.
Topics: Animals; Carcinogens; Cheek; Cricetinae; Drug Synergism; Epithelium; Gastric Mucosa; Hyperplasia; Keratosis; Leukoplakia, Oral; Male; Mesocricetus; Mouth Mucosa; Nicotine; Nitrosamines; Papilloma; Plants, Toxic; Tobacco, Smokeless | 1994 |
Modulation of oncogene and tumor suppressor gene expression in a hamster model of chronic lung injury with varying degrees of pulmonary neuroendocrine cell hyperplasia.
Topics: Animals; Base Sequence; Carcinogens; Cell Differentiation; Cell Division; Cricetinae; Diethylnitrosamine; Disease Models, Animal; DNA Primers; Female; Gene Expression Regulation; Genes, myc; Genes, p53; Genes, ras; Genes, Retinoblastoma; Genes, Tumor Suppressor; Hyperplasia; Lung; Mesocricetus; Molecular Sequence Data; Neurosecretory Systems; Nitrosamines; Oligonucleotide Probes; Oncogenes; Polymerase Chain Reaction; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Proto-Oncogenes; Transcription, Genetic | 1994 |
Increased cytosine DNA-methyltransferase activity is target-cell-specific and an early event in lung cancer.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; DNA Modification Methylases; DNA-Cytosine Methylases; Gene Expression; Hyperplasia; Lung; Lung Neoplasms; Methylation; Mice; Mice, Inbred A; Mice, Inbred C3H; Nitrosamines; Species Specificity | 1996 |
Black tea constituents, theaflavins, inhibit 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumorigenesis in A/J mice.
Topics: Animals; Antineoplastic Agents; Biflavonoids; Body Weight; Bromodeoxyuridine; Carcinogens; Catechin; Cell Division; Chemoprevention; Female; Hyperplasia; Lung Neoplasms; Mice; Mice, Inbred A; Nitrosamines; Tea; Vitamin A; Vitamin E | 1997 |
Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis.
Topics: Adenoma; Animals; Biomarkers, Tumor; Carcinogens; Carcinoma in Situ; Carcinoma, Squamous Cell; DNA Methylation; DNA, Neoplasm; Genes, p16; Humans; Hyperplasia; Lung Neoplasms; Metaplasia; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred F344; Sputum | 1998 |
Role of the alveolar type II cell in the development and progression of pulmonary tumors induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in the A/J mouse.
Topics: Adenoma; Animals; Carcinogens; Carcinoma; Female; Hyperplasia; Lung; Lung Neoplasms; Mice; Mice, Inbred A; Microscopy, Electron; Nitrosamines; Pulmonary Alveoli; Time Factors | 1992 |
Dose-response relationship between O6-methylguanine formation in Clara cells and induction of pulmonary neoplasia in the rat by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
Topics: Animals; Cell Line; DNA; Dose-Response Relationship, Drug; Guanine; Hyperplasia; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Male; Metaplasia; Methylation; Microscopy, Electron; Nitrosamines; Nose Neoplasms; Olfactory Mucosa; Rats; Rats, Inbred F344 | 1990 |