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4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and Genetic Predisposition

4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone has been researched along with Genetic Predisposition in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (80.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Angstadt, AY; Berg, A; Gallagher, CJ; Hull, A; Lazarus, P; Modesto, JL; Muscat, JE1
Huang, W; Jin, G; Jin, L; Liu, G; Lu, D; Qian, J; Shen, H; Wang, H; Wei, Q1
Andersen, B; Edwards, R; Galitovskiy, V; Gordon, W; Grando, SA1
Hao, B; He, F; Lin, D; Miao, X; Tan, W; Wang, H; Zhou, G1
Calin, GA; Croce, CM; Gnarra, JR; Huebner, K; Kaou, M; Mancini, R; Pekarsky, Y; Sevignani, C; Valtieri, M; Vecchione, A; Zanesi, N1
Howard, EF; Kanehira, T; Nakano, Y; Takagi, T; Tamura, M; Tani, T1
El-Zein, RA; Etzel, CJ; Franklin, JD; Lopez, MS; Schabath, MB; Spitz, MR1
Abdel-Aziz, HO; Hiraga, K; Hsu, DK; Kato, I; Liu, FT; Murai, Y; Nomoto, K; Tabuchi, Y; Takahashi, H; Takano, Y; Takasaki, I; Tsuneyama, K; Zheng, HC1
El-Zein, RA; Etzel, CJ; Fenech, M; Lopez, MS; Spitz, MR1
Abdel-Rahman, SZ; Au, WW; Hamada, FA; Salama, SA1

Other Studies

10 other study(ies) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and Genetic Predisposition

ArticleYear
NNK reduction pathway gene polymorphisms and risk of lung cancer.
    Molecular carcinogenesis, 2015, Volume: 54 Suppl 1

    Topics: Aged; Case-Control Studies; Female; Genetic Predisposition to Disease; Humans; Lung Neoplasms; Male; Middle Aged; Nitrosamines; Polymorphism, Single Nucleotide

2015
Genetic susceptibility of lung cancer associated with common variants in the 3' untranslated regions of the adenosine triphosphate-binding cassette B1 (ABCB1) and ABCC1 candidate transporter genes for carcinogen export.
    Cancer, 2009, Feb-01, Volume: 115, Issue:3

    Topics: 3' Untranslated Regions; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinogens; Case-Control Studies; Female; Genetic Predisposition to Disease; Humans; Lung Neoplasms; Male; Middle Aged; Multidrug Resistance-Associated Proteins; Nitrosamines; Polymorphism, Single Nucleotide; Smoking

2009
The tobacco carcinogen nitrosamine induces a differential gene expression response in tumour susceptible A/J and resistant C3H mouse lungs.
    European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:3

    Topics: Animals; Carcinogens; Genetic Predisposition to Disease; Immunity, Innate; Lung Neoplasms; Mice; Mice, Inbred C3H; Nitrosamines

2013
Substantial reduction in risk of lung adenocarcinoma associated with genetic polymorphism in CYP2A13, the most active cytochrome P450 for the metabolic activation of tobacco-specific carcinogen NNK.
    Cancer research, 2003, Nov-15, Volume: 63, Issue:22

    Topics: Adenocarcinoma; Alleles; Aryl Hydrocarbon Hydroxylases; Biotransformation; Carcinogens; Carcinoma, Squamous Cell; Case-Control Studies; Cytochrome P-450 CYP2A6; Female; Gene Deletion; Genetic Predisposition to Disease; Humans; Lung Neoplasms; Male; Middle Aged; Mixed Function Oxygenases; Nitrosamines; Polymorphism, Genetic; Smoking

2003
Lung cancer susceptibility in Fhit-deficient mice is increased by Vhl haploinsufficiency.
    Cancer research, 2005, Aug-01, Volume: 65, Issue:15

    Topics: Acid Anhydride Hydrolases; Alleles; Animals; Carcinogens; Cocarcinogenesis; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genetic Predisposition to Disease; Haploidy; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Neoplasm Proteins; Nitrosamines; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases; Von Hippel-Lindau Tumor Suppressor Protein

2005
Angiotensin II type 2 receptor gene deficiency attenuates susceptibility to tobacco-specific nitrosamine-induced lung tumorigenesis: involvement of transforming growth factor-beta-dependent cell growth attenuation.
    Cancer research, 2005, Sep-01, Volume: 65, Issue:17

    Topics: Angiotensin II Type 2 Receptor Blockers; Animals; Carcinogens; Cell Growth Processes; Cocarcinogenesis; Female; Fibroblasts; Genetic Predisposition to Disease; Humans; Lung; Lung Neoplasms; Male; Mice; Nitrosamines; Proteins; Receptor, Angiotensin, Type 2

2005
Cytokinesis-blocked micronucleus assay as a novel biomarker for lung cancer risk.
    Cancer research, 2006, Jun-15, Volume: 66, Issue:12

    Topics: Carcinogens; Case-Control Studies; Cytokinesis; DNA Repair; Female; Genetic Predisposition to Disease; Humans; Lung Neoplasms; Male; Micronuclei, Chromosome-Defective; Micronucleus Tests; Middle Aged; Nitrosamines

2006
Targeted disruption of the galectin-3 gene results in decreased susceptibility to NNK-induced lung tumorigenesis: an oligonucleotide microarray study.
    Journal of cancer research and clinical oncology, 2008, Volume: 134, Issue:7

    Topics: Adenocarcinoma; Animals; Carcinogens; Galectin 3; Gene Expression; Genetic Predisposition to Disease; Lung Neoplasms; Mice; Mice, Knockout; Nitrosamines; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction

2008
Cytokinesis-blocked micronucleus cytome assay biomarkers identify lung cancer cases amongst smokers.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2008, Volume: 17, Issue:5

    Topics: Apoptosis; Biomarkers, Tumor; Case-Control Studies; Chi-Square Distribution; Chromosome Aberrations; Cytokinesis; DNA Damage; Female; Genetic Predisposition to Disease; Humans; Logistic Models; Lung Neoplasms; Male; Micronuclei, Chromosome-Defective; Micronucleus Tests; Middle Aged; Nitrosamines; Risk Factors; Smoking; Surveys and Questionnaires

2008
Role of polymorphic CYP2E1 and CYP2D6 genes in NNK-induced chromosome aberrations in cultured human lymphocytes.
    Pharmacogenetics, 2000, Volume: 10, Issue:3

    Topics: Adult; Alleles; Carcinogenicity Tests; Carcinogens; Cells, Cultured; Chromosome Aberrations; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Genetic Predisposition to Disease; Genetic Variation; Humans; In Situ Hybridization, Fluorescence; Lymphocytes; Neoplasms; Nitrosamines; Smoking

2000