Compounds > 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone
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4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and Experimental Hepatoma

4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone has been researched along with Experimental Hepatoma in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's6 (66.67)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bäckbro, A; Beije, B; Diaz-Pohl, C; Jenssen, D; Romert, L; Swedmark, S1
Amin, S; Anderson, LM; Beebe, LE; Kim, YE; Kovatch, RM; Riggs, CW1
Anderson, MW; Castonguay, A; Chen, B; Liu, L; Maronpot, RR; You, M1
Castonguay, A; Cloutier, JF1
Amin, SG; Chung, FL; Ho, CT; Iatropoulos, MJ; Pittman, B; Reinhardt, JC; Rivenson, A; Wang, M1
Belinsky, SA; Klinge, DM; Pulling, LC1
Chung, FL; Hecht, SS; Morse, MA1
Amin, S; Anderson, LM; Dixon, DE; Dove, LF; Hecht, SS; Hoffmann, D; Kovatch, RM; Rice, JM1
Amin, S; Hecht, SS; Hoffmann, D; Prokopczyk, B; Rivenson, A1

Other Studies

9 other study(ies) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and Experimental Hepatoma

ArticleYear
Comparison of co-cultivation of V79 cells with rat hepatocytes and rat H4IIE hepatoma cells for studying nitrosamine-induced hprt gene mutations.
    Mutagenesis, 1994, Volume: 9, Issue:4

    Topics: Animals; Biotransformation; Cells, Cultured; Cricetinae; Cricetulus; Culture Techniques; Diethylnitrosamine; Dimethylnitrosamine; Dose-Response Relationship, Drug; Fibroblasts; Genes; Hypoxanthine Phosphoribosyltransferase; Liver; Liver Neoplasms, Experimental; Male; Mutagenesis; Mutagenicity Tests; Mutagens; Nicotiana; Nitrosamines; Plants, Toxic; Rats; Rats, Wistar; Tumor Cells, Cultured

1994
Comparison of transplacental and neonatal initiation of mouse lung and liver tumors by N-nitrosodimethylamine (NDMA) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and promotability by a polychlorinated biphenyls mixture (Aroclor 1254).
    Carcinogenesis, 1993, Volume: 14, Issue:8

    Topics: Animals; Animals, Newborn; Aroclors; Carcinogens; Chlorodiphenyl (54% Chlorine); Cocarcinogenesis; Dimethylnitrosamine; Female; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Maternal-Fetal Exchange; Mice; Nitrosamines; Pregnancy; Time Factors

1993
Dose-dependent ras mutation spectra in N-nitrosodiethylamine induced mouse liver tumors and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced mouse lung tumors.
    Carcinogenesis, 1993, Volume: 14, Issue:8

    Topics: Animals; Base Sequence; Diethylnitrosamine; DNA, Neoplasm; DNA, Single-Stranded; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Genes, p53; Genes, ras; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Molecular Sequence Data; Mutation; Nitrosamines; Polymerase Chain Reaction

1993
Modulation of DNA repair by various inhibitors of DNA synthesis following 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induced DNA damage.
    Chemico-biological interactions, 1998, Mar-12, Volume: 110, Issue:1-2

    Topics: Animals; Carcinogens; Cells, Cultured; DNA Damage; DNA Methylation; DNA Repair; Liver; Liver Neoplasms, Experimental; Male; Methylnitrosourea; Nitrosamines; Nucleic Acid Synthesis Inhibitors; Pyridines; Rats; Rats, Inbred F344; Tobacco Smoke Pollution; Topoisomerase I Inhibitors

1998
Inhibition of lung carcinogenesis by black tea in Fischer rats treated with a tobacco-specific carcinogen: caffeine as an important constituent.
    Cancer research, 1998, Sep-15, Volume: 58, Issue:18

    Topics: Animals; Anticarcinogenic Agents; Body Weight; Caffeine; Carcinogens; Drug Screening Assays, Antitumor; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Nose Neoplasms; Rats; Rats, Inbred F344; Survival Rate; Tea

1998
p16INK4a and beta-catenin alterations in rat liver tumors induced by NNK.
    Carcinogenesis, 2001, Volume: 22, Issue:3

    Topics: Animals; Base Sequence; beta Catenin; Cyclin-Dependent Kinase Inhibitor p16; Cytoskeletal Proteins; DNA Methylation; Humans; Liver Neoplasms, Experimental; Male; Molecular Sequence Data; Mutation; Nitrosamines; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Rats; Rats, Inbred F344; Trans-Activators

2001
Inhibition of tobacco-specific nitrosamine 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumors and DNA methylation in F344 rats and A/J mice by phenethyl isothiocyanate.
    Basic life sciences, 1990, Volume: 52

    Topics: Animals; DNA; Isothiocyanates; Liver Neoplasms, Experimental; Lung Neoplasms; Methylation; Mice; Mice, Inbred A; Nitrosamines; Nose Neoplasms; Organ Specificity; Rats; Rats, Inbred F344; Thiocyanates

1990
Evaluation of the transplacental tumorigenicity of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mice.
    Cancer research, 1989, Jul-15, Volume: 49, Issue:14

    Topics: Animals; Carcinogens; Female; Fetus; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Neoplasms, Experimental; Nicotiana; Nitrosamines; Placenta; Plants, Toxic; Pregnancy

1989
Induction of lung and exocrine pancreas tumors in F344 rats by tobacco-specific and Areca-derived N-nitrosamines.
    Cancer research, 1988, Dec-01, Volume: 48, Issue:23

    Topics: Animals; Areca; Carcinogens; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Nicotiana; Nitrosamines; Nitroso Compounds; Nose Neoplasms; Pancreatic Neoplasms; Plants, Medicinal; Plants, Toxic; Rats; Rats, Inbred F344

1988