Compounds > 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone

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4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and Carcinoma, Squamous Cell

4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone has been researched along with Carcinoma, Squamous Cell in 19 studies

Research

Studies (19)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (26.32)	18.2507
2000's	3 (15.79)	29.6817
2010's	9 (47.37)	24.3611
2020's	2 (10.53)	2.80

Authors

Authors	Studies
Chang, HJ; Chang, JY; Chou, ST; Hsiao, JR; Hsu, YM; Kuo, CC; Peng, HY; Shiah, SG; Wu, GH	1
Alam, N; Iqbal, S; Islam, M; Najnin, H; Zaidi, R	1
Chen, CT; Ko, HT; Lee, CH; Liu, TY; Tsou, HH; Wang, HT; Wang, TW	1
Chen, SF; Chu, YH; Jao, SW; Lee, TY; Lin, YS; Liu, CL; Liu, TY; Nieh, S; Tseng, YH; Yang, CY	1
Chen, L; Gao, W; Keohavong, P; Lu, C	1
Li, P; Ma, D; Sun, M; Sun, X; Wang, L; Wang, Y; Zhang, N; Zhang, S; Zhu, S	1
Dong, H; Guo, Y; Li, Y; Liang, H; Liu, Q; Meng, X; Pang, Y; Qi, X; Wang, Y; Wen, J; Xuan, B; Zhao, M; Zhou, T	1
Baldi, A; Beleford, D; Boccellino, M; Liu, Z; Maguire, J; Molina, J; Quagliuolo, L; Rattan, R; Shridhar, V; Staub, J	1
Bornstein, S; Kulesz-Martin, MF; Li, Y; Lu, SL; Malkoski, SP; Rustgi, AK; Wang, D; Wang, XJ; Weber, SM	1
Ji, WY; Li, J; Sun, X; Wang, J; Wang, LP; Xu, Y	1
Li, Y; Meng, M; Qin, CY; Wang, J; Zhao, SL	1
Hao, B; He, F; Lin, D; Miao, X; Tan, W; Wang, H; Zhou, G	1
Kim, Y; Liu, C; Liu, XS; Russell, RM; Smith, DE; Wang, XD	1
Aggarwal, BB; Deo, SV; Gupta, SD; Kaur, J; Ralhan, R; Rohatgi, N; Sawhney, M; Sethi, G; Shishodia, S; Shukla, NK	1
Hoffmann, D; Wynder, EL	1
Furukawa, F; Kleihues, P; Ohgaki, H; Takahashi, M	1
Calcagnotto, A; Hoffmann, D; Idris, AM; Kim, J; Lazarus, P	1
Lazarus, P; Park, JY; Ren, Q; Richie, JP; Schantz, SP; Sheikh, SN; Stern, JC	1
Baylin, SB; Belinsky, SA; Gabrielson, E; Herman, JG; Michels, R; Nikula, KJ; Palmisano, WA; Saccomanno, G	1

Other Studies

19 other study(ies) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and Carcinoma, Squamous Cell

Article	Year
MiR-30a and miR-379 modulate retinoic acid pathway by targeting DNA methyltransferase 3B in oral cancer. Journal of biomedical science, 2020, Apr-02, Volume: 27, Issue:1 Topics: Alcohol Oxidoreductases; Aldehyde Dehydrogenase 1 Family; Arecoline; Carcinogenesis; Carcinoma, Squamous Cell; Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3B; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Metabolic Networks and Pathways; MicroRNAs; Mitochondrial Proteins; Mouth Neoplasms; Nitrosamines; Retinal Dehydrogenase; Tretinoin	2020
Development of a Lung Cancer Model in Wistar Rat and In Silico Screening of its Biomarkers. Current computer-aided drug design, 2021, Volume: 17, Issue:3 Topics: Adenocarcinoma of Lung; Animals; Biomarkers, Tumor; Carcinoma, Squamous Cell; Computer Simulation; Disease Models, Animal; Drug Design; ErbB Receptors; Lung Neoplasms; Male; Molecular Docking Simulation; Molecular Targeted Therapy; Nitrosamines; Rats; Rats, Wistar	2021
Betel quid containing safrole enhances metabolic activation of tobacco specific 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). Environmental pollution (Barking, Essex : 1987), 2019, Volume: 251 Topics: Activation, Metabolic; Animals; Carcinoma, Squamous Cell; Cricetinae; Cytochrome P-450 CYP2A6; Female; Humans; Liver; Mouth Neoplasms; Nicotiana; Nitrosamines; Safrole; Taiwan; Tobacco Use	2019
Regulation of tumor progression via the Snail-RKIP signaling pathway by nicotine exposure in head and neck squamous cell carcinoma. Head & neck, 2015, Volume: 37, Issue:12 Topics: Aldehyde Dehydrogenase 1 Family; alpha7 Nicotinic Acetylcholine Receptor; Apoptosis; Carcinogens; Carcinoma, Squamous Cell; Cell Culture Techniques; Cell Line, Tumor; Cell Movement; Disease Progression; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Head and Neck Neoplasms; Humans; Hypopharyngeal Neoplasms; Isoenzymes; Mouth Neoplasms; Neoplasm Invasiveness; Neoplasm Staging; Neoplastic Stem Cells; Nicotine; Nicotinic Agonists; Nitrosamines; Retinal Dehydrogenase; Signal Transduction; Snail Family Transcription Factors; Tongue Neoplasms; Transcription Factors; Up-Regulation	2015
Overexpression of CRM1: A Characteristic Feature in a Transformed Phenotype of Lung Carcinogenesis and a Molecular Target for Lung Cancer Adjuvant Therapy. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2015, Volume: 10, Issue:5 Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Cycle Checkpoints; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Cisplatin; Cyclin-Dependent Kinase Inhibitor p21; Exportin 1 Protein; Fatty Acids, Unsaturated; Female; Gene Expression; Gene Silencing; Humans; Inhibitor of Apoptosis Proteins; Karyopherins; Lung; Lung Neoplasms; Male; Mice; Mice, Nude; Middle Aged; Nitrosamines; Phosphorylation; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Smoking; Survivin; Transfection; Tumor Stem Cell Assay; Tumor Suppressor Protein p53	2015
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone promotes esophageal squamous cell carcinoma growth via beta-adrenoceptors in vitro and in vivo. PloS one, 2015, Volume: 10, Issue:3 Topics: Adrenergic beta-Antagonists; Carcinogens; Carcinoma, Squamous Cell; Cell Line, Tumor; Esophageal Neoplasms; Humans; In Vitro Techniques; Nitrosamines; Receptors, Adrenergic, beta; RNA Interference; RNA, Small Interfering	2015
Essential role of Na+/Ca2+ exchanger 1 in smoking-induced growth and migration of esophageal squamous cell carcinoma. Oncotarget, 2016, Sep-27, Volume: 7, Issue:39 Topics: Benzyl Compounds; Calcium; Carcinoma, Squamous Cell; Cell Line; Cell Line, Tumor; Cell Movement; Cell Proliferation; Epithelial Cells; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Humans; Nitrosamines; Risk Factors; Smoking; Sodium; Sodium-Calcium Exchanger; Thiazolidines; Thiourea; Tobacco Products	2016
Methylation induced gene silencing of HtrA3 in smoking-related lung cancer. Clinical cancer research : an official journal of the American Association for Cancer Research, 2010, Jan-15, Volume: 16, Issue:2 Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Large Cell; Carcinoma, Squamous Cell; Cell Line, Tumor; Cells, Cultured; Cisplatin; DNA Methylation; Drug Resistance, Neoplasm; Etoposide; Gene Silencing; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Nitrosamines; Serine Endopeptidases; Smoking	2010
Tobacco-specific carcinogen nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induces AKT activation in head and neck epithelia. International journal of oncology, 2011, Volume: 39, Issue:5 Topics: Animals; Apoptosis; Carcinogens; Carcinoma, Squamous Cell; Cell Line; Cell Proliferation; Enzyme Activation; Head and Neck Neoplasms; Humans; Mice; Mice, Inbred C57BL; Nicotiana; Nitrosamines; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Squamous Cell Carcinoma of Head and Neck	2011
The tobacco-specific carcinogen NNK induces DNA methyltransferase 1 accumulation in laryngeal carcinoma. Oral oncology, 2012, Volume: 48, Issue:6 Topics: Adult; Aged; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Female; Humans; Laryngeal Neoplasms; Male; Middle Aged; Nitrosamines; Prognosis; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; RNA, Messenger; Smoking	2012
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone induces retinoic acid receptor β hypermethylation through DNA methyltransferase 1 accumulation in esophageal squamous epithelial cells. Asian Pacific journal of cancer prevention : APJCP, 2012, Volume: 13, Issue:5 Topics: Apoptosis; Blotting, Western; Carcinogens; Carcinoma, Squamous Cell; Cell Proliferation; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Esophageal Neoplasms; Humans; Nitrosamines; Real-Time Polymerase Chain Reaction; Receptors, Retinoic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured	2012
Substantial reduction in risk of lung adenocarcinoma associated with genetic polymorphism in CYP2A13, the most active cytochrome P450 for the metabolic activation of tobacco-specific carcinogen NNK. Cancer research, 2003, Nov-15, Volume: 63, Issue:22 Topics: Adenocarcinoma; Alleles; Aryl Hydrocarbon Hydroxylases; Biotransformation; Carcinogens; Carcinoma, Squamous Cell; Case-Control Studies; Cytochrome P-450 CYP2A6; Female; Gene Deletion; Genetic Predisposition to Disease; Humans; Lung Neoplasms; Male; Middle Aged; Mixed Function Oxygenases; Nitrosamines; Polymorphism, Genetic; Smoking	2003
Induction of pulmonary neoplasia in the smoke-exposed ferret by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK): a model for human lung cancer. Cancer letters, 2006, Mar-28, Volume: 234, Issue:2 Topics: Adenocarcinoma; Animals; Carcinogens; Carcinoma, Squamous Cell; Disease Models, Animal; Ferrets; Humans; Immunohistochemistry; Lung Neoplasms; Male; Nitrosamines; Precancerous Conditions; Smoking	2006
Expression of NF-kappaB parallels COX-2 expression in oral precancer and cancer: association with smokeless tobacco. International journal of cancer, 2007, Jun-15, Volume: 120, Issue:12 Topics: Adult; Aged; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Chi-Square Distribution; Cyclooxygenase 2; Cytoplasm; Dose-Response Relationship, Drug; Female; Humans; Immunohistochemistry; Male; Membrane Proteins; Microscopy, Confocal; Middle Aged; Mouth Neoplasms; NF-kappa B; Nitrosamines; Oligonucleotides; Plant Extracts; Precancerous Conditions; Protein Binding; Time Factors; Tobacco, Smokeless	2007
Smoking and lung cancer: scientific challenges and opportunities. Cancer research, 1994, Oct-15, Volume: 54, Issue:20 Topics: Adenocarcinoma; Black or African American; Black People; Carcinoma, Squamous Cell; Disease Susceptibility; Female; Humans; Incidence; Japan; Lung Neoplasms; Male; Nitrosamines; Risk Factors; Sex Factors; Smoking; Tobacco Smoke Pollution; United Kingdom; United States; White People	1994
K-ras mutations are frequent in pulmonary squamous cell carcinomas but not in adenocarcinomas of WBN/Kob rats induced by N-nitrosobis(2-oxopropyl)amine. Carcinogenesis, 1993, Volume: 14, Issue:7 Topics: Adenocarcinoma; Animals; Base Sequence; Carcinoma, Squamous Cell; DNA, Single-Stranded; Genes, ras; Lung Neoplasms; Male; Molecular Sequence Data; Nitrosamines; Point Mutation; Rats	1993
p53 mutations in head and neck squamous cell carcinomas from Sudanese snuff (toombak) users. Cancer detection and prevention, 1996, Volume: 20, Issue:4 Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Genes, p53; Genes, ras; Head and Neck Neoplasms; Humans; Mice; Mutation; Nitrosamines; Plants, Toxic; Polymorphism, Single-Stranded Conformational; Tobacco, Smokeless	1996
p53, but not p16 mutations in oral squamous cell carcinomas are associated with specific CYP1A1 and GSTM1 polymorphic genotypes and patient tobacco use. Carcinogenesis, 1998, Volume: 19, Issue:3 Topics: Benzo(a)pyrene; Carcinoma, Squamous Cell; Cyclin-Dependent Kinase Inhibitor p16; Cytochrome P-450 CYP1A1; Exons; Genes, p53; Genotype; Glutathione Transferase; Humans; Mouth Neoplasms; Mutation; Nicotiana; Nitrosamines; Plants, Toxic; Polymorphism, Genetic; Smoking	1998
Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis. Proceedings of the National Academy of Sciences of the United States of America, 1998, Sep-29, Volume: 95, Issue:20 Topics: Adenoma; Animals; Biomarkers, Tumor; Carcinogens; Carcinoma in Situ; Carcinoma, Squamous Cell; DNA Methylation; DNA, Neoplasm; Genes, p16; Humans; Hyperplasia; Lung Neoplasms; Metaplasia; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred F344; Sputum	1998