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4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and Carcinoma, Non-Small Cell Lung

4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone has been researched along with Carcinoma, Non-Small Cell Lung in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.25)18.2507
2000's5 (31.25)29.6817
2010's10 (62.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bai, R; Bode, AM; Chang, X; Dong, Z; Li, X; Liu, K; Ma, W; Ryu, J; Song, Y; Wang, K; Wang, Q; Wang, T; Xia, Q; Zhang, T1
Charoensinphon, N; Han, Y; Qiu, P; Song, M; Sun, Y; Wu, X; Xiao, H; Zheng, J1
Harada, D; Hotta, K; Ichihara, E; Kiura, K; Ochi, N; Tabata, M; Takigawa, N; Tanimoto, M; Yasugi, M1
Brooks, GD; Jenkins, BJ; McLeod, L; Miller, A; Ruwanpura, S1
Chen, L; Gao, W; Keohavong, P; Lu, C1
Bora, HK; Farhan, M; Khan, S; Kumar, S; Maurya, R; Meeran, SM; Shukla, S; Sinha, S1
Chen, GG; Du, J; Huang, R; Li, MY; Liu, Y; Long, X; Mok, TS; Ng, CS; Underwood, MJ; Wan, IY; Wu, B; Wu, J; Yang, S1
Khan, S; Kumar, S; Maurya, R; Meeran, SM; Mitra, K; Shukla, S; Singh, K; Sinha, S1
Linnoila, RI; Naizhen, X; Poulsen, HS; Poulsen, TT1
Spindel, ER1
Chen, GG; Hsin, MK; Kong, AW; Li, MY; Ma, LT; Underwood, MJ; Yip, JH; Yuan, H1
Chen, GG; Hsin, MK; Li, MY; Ma, LT; Mok, TS; Underwood, MJ; Yuan, H1
Brognard, J; Castillo, SS; Dennis, PA; Gills, JJ; Granville, CA; Sayyah, J; Tsurutani, J; Zhang, C1
Cekanova, M; Schuller, HM1
Hisamoto, A; Hosokawa, S; Kiura, K; Kondo, E; Mimoto, J; Okada, T; Tabata, M; Takigawa, N; Tanimoto, M1
Jarrard, JA; Lee, H; Linnoila, RI; Steinberg, SM; Szabo, E; Witschi, H1

Other Studies

16 other study(ies) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and Carcinoma, Non-Small Cell Lung

ArticleYear
Fluvastatin Inhibits HMG-CoA Reductase and Prevents Non-Small Cell Lung Carcinogenesis.
    Cancer prevention research (Philadelphia, Pa.), 2019, Volume: 12, Issue:12

    Topics: Acyl Coenzyme A; Adult; Aged; Animals; Apoptosis; Carcinogenesis; Carcinogens; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Female; Fluvastatin; Gene Knockdown Techniques; HEK293 Cells; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lung; Lung Neoplasms; Male; Mevalonic Acid; Mice; Middle Aged; Neoplasms, Experimental; Nitrosamines; RNA, Small Interfering; Xenograft Model Antitumor Assays

2019
Inhibitory effects of nobiletin and its major metabolites on lung tumorigenesis.
    Food & function, 2019, Nov-01, Volume: 10, Issue:11

    Topics: Animals; Antioxidants; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Female; Flavones; Humans; Mice; Neoplasms, Experimental; Nitrosamines

2019
Src mediates ERK reactivation in gefitinib resistance in non-small cell lung cancer.
    Experimental cell research, 2014, Mar-10, Volume: 322, Issue:1

    Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Resistance, Neoplasm; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Gefitinib; Humans; Lung Neoplasms; Nitrosamines; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins pp60(c-src); Quinazolines

2014
Differential involvement of gp130 signalling pathways in modulating tobacco carcinogen-induced lung tumourigenesis.
    Oncogene, 2015, Mar-19, Volume: 34, Issue:12

    Topics: Animals; Carcinogens; Carcinoma, Non-Small-Cell Lung; Cell Line; Cell Proliferation; Cytokine Receptor gp130; Female; Gene Expression Regulation, Neoplastic; Humans; Interleukin-6; Lung Neoplasms; Male; MAP Kinase Signaling System; Mice; Nitrosamines

2015
Overexpression of CRM1: A Characteristic Feature in a Transformed Phenotype of Lung Carcinogenesis and a Molecular Target for Lung Cancer Adjuvant Therapy.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2015, Volume: 10, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Cycle Checkpoints; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Cisplatin; Cyclin-Dependent Kinase Inhibitor p21; Exportin 1 Protein; Fatty Acids, Unsaturated; Female; Gene Expression; Gene Silencing; Humans; Inhibitor of Apoptosis Proteins; Karyopherins; Lung; Lung Neoplasms; Male; Mice; Mice, Nude; Middle Aged; Nitrosamines; Phosphorylation; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Smoking; Survivin; Transfection; Tumor Stem Cell Assay; Tumor Suppressor Protein p53

2015
Cucurbitacin B Alters the Expression of Tumor-Related Genes by Epigenetic Modifications in NSCLC and Inhibits NNK-Induced Lung Tumorigenesis.
    Cancer prevention research (Philadelphia, Pa.), 2015, Volume: 8, Issue:6

    Topics: Animals; Apoptosis; Blotting, Southwestern; Blotting, Western; Carcinogens; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Proliferation; Cell Transformation, Neoplastic; Chromatin Immunoprecipitation; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Histone Deacetylases; Humans; Immunoenzyme Techniques; Lung Neoplasms; Mice; Mice, Inbred A; Nitrosamines; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Triterpenes; Tumor Cells, Cultured

2015
Tumorigenesis of smoking carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone is related to its ability to stimulate thromboxane synthase and enhance stemness of non-small cell lung cancer stem cells.
    Cancer letters, 2016, Jan-28, Volume: 370, Issue:2

    Topics: beta Catenin; Carcinogens; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Humans; Lung Neoplasms; Neoplastic Stem Cells; Nitrosamines; Thromboxane-A Synthase

2016
Cucurbitacin B inhibits the stemness and metastatic abilities of NSCLC via downregulation of canonical Wnt/β-catenin signaling axis.
    Scientific reports, 2016, Feb-24, Volume: 6

    Topics: A549 Cells; Animals; beta Catenin; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Down-Regulation; Epithelial-Mesenchymal Transition; Female; Human Umbilical Vein Endothelial Cells; Humans; Immunoprecipitation; Lung Neoplasms; Mice; Microscopy, Fluorescence; Neovascularization, Physiologic; Nitrosamines; RNA Interference; RNA, Small Interfering; Transforming Growth Factor beta1; Triterpenes; Wnt Signaling Pathway; Wnt3 Protein; Wnt3A Protein

2016
Acute damage by naphthalene triggers expression of the neuroendocrine marker PGP9.5 in airway epithelial cells.
    Toxicology letters, 2008, Sep-26, Volume: 181, Issue:2

    Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cyclin-Dependent Kinase Inhibitor p27; Epithelial Cells; Hyperplasia; Lung; Lung Neoplasms; Male; Mice; Naphthalenes; Neurosecretory Systems; Nitrosamines; RNA, Messenger; Ubiquitin Thiolesterase

2008
Is nicotine the estrogen of lung cancer?
    American journal of respiratory and critical care medicine, 2009, Jun-15, Volume: 179, Issue:12

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Bungarotoxins; Carcinogens; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Lung; Lung Neoplasms; Nicotine; Nitrosamines; Prognosis; Receptors, Nicotinic; Risk Factors; Tobacco Smoke Pollution

2009
Roles of peroxisome proliferator-activated receptor-alpha and -gamma in the development of non-small cell lung cancer.
    American journal of respiratory cell and molecular biology, 2010, Volume: 43, Issue:6

    Topics: Animals; Carcinoma, Non-Small-Cell Lung; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Humans; Hydroxyeicosatetraenoic Acids; Ligands; Linoleic Acids; Lipid Metabolism; Lung Neoplasms; Male; Mice; Nitrosamines; Pioglitazone; PPAR alpha; PPAR gamma; Precancerous Conditions; Retinoid X Receptor alpha; Signal Transduction; Thiazolidinediones; Transcription, Genetic

2010
15-Lipoxygenases and its metabolites 15(S)-HETE and 13(S)-HODE in the development of non-small cell lung cancer.
    Thorax, 2010, Volume: 65, Issue:4

    Topics: Animals; Arachidonate 15-Lipoxygenase; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Cell Transformation, Neoplastic; Disease Models, Animal; Disease Progression; Female; Humans; Hydroxyeicosatetraenoic Acids; Linoleic Acids; Lung; Lung Neoplasms; Mice; Mice, Inbred A; Neoplasm Proteins; Nitrosamines; PPAR gamma

2010
Tobacco components stimulate Akt-dependent proliferation and NFkappaB-dependent survival in lung cancer cells.
    Carcinogenesis, 2005, Volume: 26, Issue:7

    Topics: Carcinogens; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Proliferation; Cell Survival; Ganglionic Stimulants; Humans; Lung; Lung Neoplasms; NF-kappa B; Nicotine; Nitrosamines; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Smoking; Tumor Cells, Cultured

2005
NNK-induced hamster lung adenocarcinomas over-express beta2-adrenergic and EGFR signaling pathways.
    Lung cancer (Amsterdam, Netherlands), 2005, Volume: 49, Issue:1

    Topics: Adenocarcinoma; Animals; Carcinogens; Carcinoma, Non-Small-Cell Lung; Cricetinae; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; ErbB Receptors; Gene Expression Profiling; Immunohistochemistry; Lung Neoplasms; Male; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Protein Serine-Threonine Kinases; Receptors, Adrenergic, beta-2; Signal Transduction

2005
Point mutation of K-ras gene in cisplatin-induced lung tumours in A/J mice.
    Lung cancer (Amsterdam, Netherlands), 2007, Volume: 58, Issue:1

    Topics: Adenocarcinoma; Animals; Benzo(a)pyrene; Carcinogens; Carcinoma, Non-Small-Cell Lung; Cisplatin; Codon; Female; Genes, ras; Lung Neoplasms; Mice; Neoplasms, Experimental; Neoplasms, Second Primary; Nitrosamines; Point Mutation

2007
MUC1 is a novel marker for the type II pneumocyte lineage during lung carcinogenesis.
    Cancer research, 1998, Dec-01, Volume: 58, Issue:23

    Topics: Animals; Biomarkers, Tumor; Carcinogens; Carcinoma, Non-Small-Cell Lung; Cell Differentiation; Cell Lineage; Cricetinae; Down-Regulation; Female; Histone Deacetylase Inhibitors; Humans; Immunohistochemistry; Lung; Lung Neoplasms; Male; Mesocricetus; Middle Aged; Mucin-1; Nitrosamines; Oligopeptides; Peptide Fragments; Pulmonary Alveoli; RNA, Messenger

1998