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4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide and Muscle Contraction

4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide has been researched along with Muscle Contraction in 10 studies

*Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments. [MeSH]

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (50.00)18.2507
2000's3 (30.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Becketts, K; Bilsky, EJ; Calderon, SN; Davis, P; Flippen-Anderson, JL; Horvath, R; Kayakiri, H; Porreca, F; Rice, KC; Rothman, RB; Smith, LE; Xu, H1
Becketts, K; Calderon, SN; Davis, P; Flippen-Anderson, JL; Foltz, EJ; Homma, K; Katsura, Y; Porreca, F; Rice, KC; Rothman, RB; Xu, H; Yamamura, HI; Zhang, X1
Alfaro-Lopez, J; Davis, P; Hosohata, K; Hruby, VJ; Jernigan, KA; Li, X; Liao, S; Lin, J; Porreca, F; Shenderovich, MD; Stropova, D; Yamamura, HI1
Coop, A; Davis, P; Dersch, C; Jacobson, AE; Partilla, J; Porreca, F; Rice, KC; Rothman, RB1
Calderon, SN; Coop, A; Davis, P; Dersch, CM; Jacobson, AE; Kayakiri, H; Porreca, F; Rice, KC; Rothman, RB; Smith, L; Zhang, X1
Ananthan, S; Bartlett, JL; Bilsky, EJ; Davis, P; Dersch, CM; Khare, NK; Porreca, F; Rothman, RB; Saini, SK; Seitz, LE1
Bunnett, NW; Canals, M; Carbone, SE; DiCello, JJ; Eriksson, EM; Fichna, J; McQuade, RM; Nowell, CJ; Poole, DP; Rajasekhar, P; Saito, A; Sebastian, BW; Veldhuis, NA1
Canals, M; Carbone, SE; DiCello, JJ; Gondin, AB; McQuade, RM; Poole, DP; Rajasekhar, P; Saito, A; Sebastian, BW; Veldhuis, NA1
Ahmadiani, A; Dehpour, AR; Joharchi, K; Jorjani, M; Rastegar, H; Roushanzamir, F1
Broom, DC; Coop, A; Guo, L; Husbands, SM; Lewis, JW; Traynor, JR; Woods, JH1

Other Studies

10 other study(ies) available for 4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide and Muscle Contraction

ArticleYear
Probes for narcotic receptor mediated phenomena. 23. Synthesis, opioid receptor binding, and bioassay of the highly selective delta agonist (+)-4-[(alpha R)-alpha-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]- N,N-diethylbenzamide (SNC 80)
    Journal of medicinal chemistry, 1997, Feb-28, Volume: 40, Issue:5

    Topics: Animals; Benzamides; Binding, Competitive; Brain; Crystallography, X-Ray; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; Ileum; Magnetic Resonance Spectroscopy; Male; Mice; Molecular Conformation; Molecular Structure; Muscle Contraction; Piperazines; Radioligand Assay; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Stereoisomerism; Vas Deferens

1997
Probes for narcotic receptor-mediated phenomena. 25. Synthesis and evaluation of N-alkyl-substituted (alpha-piperazinylbenzyl)benzamides as novel, highly selective delta opioid receptor agonists.
    Journal of medicinal chemistry, 1997, Aug-29, Volume: 40, Issue:18

    Topics: Alkylation; Animals; Benzamides; Brain; Cell Membrane; CHO Cells; Cricetinae; Crystallography, X-Ray; Guinea Pigs; Humans; Kinetics; Male; Mice; Mice, Inbred ICR; Models, Molecular; Molecular Conformation; Molecular Structure; Muscle Contraction; Muscle, Smooth; Narcotics; Piperazines; Radioligand Assay; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Structure-Activity Relationship; Transfection; Vas Deferens

1997
De novo design, synthesis, and biological activities of high-affinity and selective non-peptide agonists of the delta-opioid receptor.
    Journal of medicinal chemistry, 1998, Nov-19, Volume: 41, Issue:24

    Topics: Animals; Benzhydryl Compounds; Brain; Drug Design; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Ligands; Male; Mice; Mice, Inbred ICR; Molecular Mimicry; Muscle Contraction; Muscle, Smooth; Mutation; Peptides; Piperazines; Radioligand Assay; Rats; Receptors, Opioid, delta; Stereoisomerism; Structure-Activity Relationship; Vas Deferens

1998
delta Opioid affinity and selectivity of 4-hydroxy-3-methoxyindolomorphinan analogues related to naltrindole.
    Journal of medicinal chemistry, 1999, May-06, Volume: 42, Issue:9

    Topics: Animals; Binding, Competitive; Brain; Guanosine 5'-O-(3-Thiotriphosphate); Ileum; In Vitro Techniques; Indoles; Ligands; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Muscle, Smooth; Naltrexone; Narcotic Antagonists; Rabbits; Receptors, Opioid, delta; Vas Deferens

1999
Probes for narcotic receptor mediated phenomena. 26. Synthesis and biological evaluation of diarylmethylpiperazines and diarylmethylpiperidines as novel, nonpeptidic delta opioid receptor ligands.
    Journal of medicinal chemistry, 1999, Dec-30, Volume: 42, Issue:26

    Topics: Animals; Brain; Guinea Pigs; In Vitro Techniques; Ligands; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Mice, Inbred ICR; Molecular Probes; Muscle Contraction; Muscle, Smooth; Piperazines; Radioligand Assay; Rats; Receptors, Opioid, delta; Structure-Activity Relationship

1999
Identification of opioid ligands possessing mixed micro agonist/delta antagonist activity among pyridomorphinans derived from naloxone, oxymorphone, and hydromorphone [correction of hydropmorphone].
    Journal of medicinal chemistry, 2004, Mar-11, Volume: 47, Issue:6

    Topics: Analgesics; Animals; Binding Sites; Brain; Drug Tolerance; Electric Stimulation; Guinea Pigs; Hydromorphone; Ileum; In Vitro Techniques; Ligands; Male; Mice; Mice, Inbred ICR; Morphinans; Muscle Contraction; Muscle, Smooth; Naloxone; Oxymorphone; Pyridines; Radioligand Assay; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Vas Deferens

2004
Inflammation-associated changes in DOR expression and function in the mouse colon.
    American journal of physiology. Gastrointestinal and liver physiology, 2018, 10-01, Volume: 315, Issue:4

    Topics: Animals; Benzamides; Colitis, Ulcerative; Colon; Endocytosis; Enkephalin, Leucine-2-Alanine; Enteric Nervous System; Female; Gastrointestinal Motility; Male; Mice; Mice, Inbred C57BL; Muscle Contraction; Oligopeptides; Piperazines; Receptors, Opioid, delta

2018
Agonist-dependent development of delta opioid receptor tolerance in the colon.
    Cellular and molecular life sciences : CMLS, 2019, Volume: 76, Issue:15

    Topics: Analgesics, Opioid; Animals; Benzamides; Colon; Drug Tolerance; Electric Stimulation; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Muscle Contraction; Neurons; Piperazines; Receptors, Opioid, delta; Receptors, Opioid, mu

2019
Subsensitivity to opioids is receptor-specific in isolated guinea pig ileum and mouse vas deferens after obstructive cholestasis.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 293, Issue:3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzamides; Cholestasis; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Morphine; Muscle Contraction; Narcotics; Piperazines; Receptors, Opioid; Time Factors; Vas Deferens

2000
BU48: a novel buprenorphine analog that exhibits delta-opioid-mediated convulsions but not delta-opioid-mediated antinociception in mice.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:3

    Topics: Analgesics, Opioid; Animals; Benzamides; Brain; Buprenorphine; Convulsants; Electric Stimulation; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Naltrexone; Narcotic Antagonists; Pain Measurement; Piperazines; Radioligand Assay; Rats; Receptors, Opioid, delta; Receptors, Opioid, kappa; Seizures; Vas Deferens

2000