Compounds > 4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide

Page last updated: 2024-09-03

4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide and Innate Inflammatory Response

4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide has been researched along with Innate Inflammatory Response in 11 studies

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	6 (54.55)	29.6817
2010's	5 (45.45)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Evans, C; McGuire, B; Pradhan, A; Smith, M; Walwyn, W	1
Ko, MC; Lee, H; Rice, KC; Sukhtankar, DD	1
Gavériaux-Ruff, C; Hever, X; Karchewski, LA; Kieffer, BL; Matifas, A	1
Erbs, E; Evans, C; Filliol, D; Kieffer, BL; Matifas, A; Nozaki, C; Pradhan, AA; Walwyn, W	1
Filliol, D; Gaveriaux-Ruff, C; Hever, XC; Kieffer, BL; Maldonado, R; Matifas, A; Nadal, X; Nassar, MA; Nozaki, C; Reiss, D; Weibel, R; Wood, JN	1
Dolle, RE; Gavériaux-Ruff, C; Kieffer, BL; Le Bourdonnec, B; Little, PJ; Nozaki, C; Reiss, D; Windh, RT	1
Chandran, P; Sluka, KA	1
Planas, E; Pol, O; Poveda, R; Puig, MM; Romero, A; Sánchez, S	1
Ducharme, J; Ducharme, MP; Lessard, E; Projean, D	1
Hingne, PM; Sluka, KA	1
Cao, CQ; Dray, A; Hong, Y; Perkins, M	1

Other Studies

11 other study(ies) available for 4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide and Innate Inflammatory Response

Article	Year
Chronic inflammatory injury results in increased coupling of delta opioid receptors to voltage-gated Ca2+ channels. Molecular pain, 2013, Mar-04, Volume: 9 Topics: Animals; Arrestins; Benzamides; beta-Arrestin 2; beta-Arrestins; Calcium Channels; Chronic Disease; Chronic Pain; Freund's Adjuvant; Ganglia, Spinal; Hyperalgesia; Inflammation; Ion Channel Gating; Mice; Mice, Knockout; Pain Threshold; Piperazines; Receptors, Opioid, delta	2013
Differential effects of opioid-related ligands and NSAIDs in nonhuman primate models of acute and inflammatory pain. Psychopharmacology, 2014, Volume: 231, Issue:7 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acute Pain; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fentanyl; Hyperalgesia; Imidazoles; Inflammation; Macaca; Male; Nociceptive Pain; Pain Measurement; Piperazines; Receptors, Opioid; Spiro Compounds	2014
Inflammatory pain is enhanced in delta opioid receptor-knockout mice. The European journal of neuroscience, 2008, Volume: 27, Issue:10 Topics: Analgesics, Opioid; Animals; Benzamides; Brain; Female; Freund's Adjuvant; Hyperalgesia; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Nociceptors; Pain; Piperazines; Receptors, Opioid, delta	2008
Ligand-directed trafficking of the δ-opioid receptor in vivo: two paths toward analgesic tolerance. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Dec-08, Volume: 30, Issue:49 Topics: Analgesics; Animals; Benzamides; Brain; Calcium; Cell Membrane; Disease Models, Animal; Drug Interactions; Drug Tolerance; Female; Freund's Adjuvant; Ganglia, Spinal; Green Fluorescent Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hyperalgesia; Inflammation; Ligands; Locomotion; Male; Maze Learning; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pain; Pain Threshold; Patch-Clamp Techniques; Piperazines; Piperidines; Protein Binding; Protein Transport; Receptors, Opioid, delta; Sensory Receptor Cells; Spinal Cord; Statistics, Nonparametric; Sulfur Isotopes; Time Factors	2010
Genetic ablation of delta opioid receptors in nociceptive sensory neurons increases chronic pain and abolishes opioid analgesia. Pain, 2011, Volume: 152, Issue:6 Topics: Analgesics, Opioid; Analysis of Variance; Animals; Benzamides; Disease Models, Animal; Dose-Response Relationship, Drug; Freund's Adjuvant; Ganglia, Spinal; Guanosine 5'-O-(3-Thiotriphosphate); Inflammation; Mice; Mice, Inbred C57BL; Motor Activity; NAV1.8 Voltage-Gated Sodium Channel; Nociceptors; Pain; Pain Measurement; Piperazines; Protein Binding; Receptors, Opioid, delta; Sodium Channels; Sulfur Isotopes	2011
δ-Opioid mechanisms for ADL5747 and ADL5859 effects in mice: analgesia, locomotion, and receptor internalization. The Journal of pharmacology and experimental therapeutics, 2012, Volume: 342, Issue:3 Topics: Analgesia; Analgesics, Opioid; Animals; Benzamides; Benzopyrans; Disease Models, Animal; Gene Knock-In Techniques; Humans; Inflammation; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; NAV1.8 Voltage-Gated Sodium Channel; Neuralgia; Neurons; Pain Measurement; Piperazines; Receptors, Opioid, delta; Spiro Compounds	2012
Development of opioid tolerance with repeated transcutaneous electrical nerve stimulation administration. Pain, 2003, Volume: 102, Issue:1-2 Topics: Animals; Benzamides; Dose-Response Relationship, Drug; Drug Tolerance; Inflammation; Knee Joint; Male; Morphine; Pain; Pain Measurement; Physical Stimulation; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Transcutaneous Electric Nerve Stimulation	2003
Anti-exudative effects of opioid receptor agonists in a rat model of carrageenan-induced acute inflammation of the paw. European journal of pharmacology, 2005, Mar-28, Volume: 511, Issue:2-3 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Benzamides; Capsaicin; Carrageenan; Cyclosporine; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Enkephalin, D-Penicillamine (2,5)-; Extravasation of Diagnostic and Therapeutic Materials; Fentanyl; Hindlimb; Histamine Antagonists; Inflammation; Male; Morphine; Narcotic Antagonists; Oxidopamine; p-Methoxy-N-methylphenethylamine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	2005
Use of Freund's Complete Adjuvant (FCA) in inflammatory pain models: consequences on the metabolism and pharmacokinetics of the non-peptidic delta receptor agonist SNC80 in the rat. Xenobiotica; the fate of foreign compounds in biological systems, 2007, Volume: 37, Issue:8 Topics: Animals; Benzamides; Biological Availability; Blood Proteins; Cytochrome P-450 Enzyme System; Disease Models, Animal; Freund's Adjuvant; Glycoproteins; Humans; Inflammation; Male; Microsomes, Liver; Orosomucoid; Pain; Piperazines; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Recombinant Proteins; Solutions	2007
Blockade of NMDA receptors prevents analgesic tolerance to repeated transcutaneous electrical nerve stimulation (TENS) in rats. The journal of pain, 2008, Volume: 9, Issue:3 Topics: Analgesics; Animals; Behavior, Animal; Benzamides; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Drug Tolerance; Excitatory Amino Acid Antagonists; Inflammation; Knee Joint; Male; Pain Measurement; Pain Threshold; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Time Factors; Transcutaneous Electric Nerve Stimulation	2008
Spinal delta-opioid receptors mediate suppression of systemic SNC80 on excitability of the flexor reflex in normal and inflamed rat. European journal of pharmacology, 2001, Apr-20, Volume: 418, Issue:1-2 Topics: Afferent Pathways; Animals; Benzamides; Central Nervous System; Conditioning, Psychological; Dose-Response Relationship, Drug; Drug Hypersensitivity; Electric Stimulation; Electrophysiology; Freund's Adjuvant; Hindlimb; Indoles; Inflammation; Male; Morphinans; Motor Neurons; Naloxone; Narcotic Antagonists; Pain Measurement; Piperazines; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Reflex; Somatostatin; Tartrates; Touch	2001