4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide has been researched along with Allodynia in 19 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 6 (31.58) | 29.6817 |
2010's | 12 (63.16) | 24.3611 |
2020's | 1 (5.26) | 2.80 |
Authors | Studies |
---|---|
Baca, SM; Bertels, Z; Dripps, IJ; Kieffer, BL; Moye, LS; Pradhan, AA; Siegersma, K; Tipton, AF | 1 |
Leánez, S; McDonnell, C; Pol, O | 1 |
Boyer, BT; Dripps, IJ; Jutkiewicz, EM; Neubig, RR; Rice, KC; Traynor, JR | 1 |
Crombie, A; Dripps, I; Moye, LS; Pradhan, AA; Sheets, Z; Tipton, AF; Violin, JD | 1 |
Evans, C; McGuire, B; Pradhan, A; Smith, M; Walwyn, W | 1 |
Ko, MC; Lee, H; Rice, KC; Sukhtankar, DD | 1 |
Charles, A; Pradhan, AA; Smith, ML; Zyuzin, J | 1 |
Gaveriaux-Ruff, C; Kieffer, BL; Matifas, A; Nagase, H; Nemoto, T; Nozaki, C | 1 |
Doyle, AP; Gomez, R; Henry, MA; Jeske, NA; Rowan, MP; Szteyn, K | 1 |
Bana, A; Evans, CJ; Kieffer, BL; Perroy, J; Pradhan, AA; Segura, L; Smith, ML; Vicente-Sanchez, A; Walwyn, WM | 1 |
Dripps, IJ; Jutkiewicz, EM; Neubig, RR; Rice, KC; Traynor, JR; Wang, Q | 1 |
Gavériaux-Ruff, C; Hever, X; Karchewski, LA; Kieffer, BL; Matifas, A | 1 |
da Silva, LFS; DeSantana, JM; Sluka, KA | 1 |
Erbs, E; Evans, C; Filliol, D; Kieffer, BL; Matifas, A; Nozaki, C; Pradhan, AA; Walwyn, W | 1 |
Bussey, RA; Eikenberry, SA; Rohlwing, JJ; Sluka, KA; Wilken, JM | 1 |
Gallantine, EL; Meert, TF | 1 |
Castro, MS; Duarte, ID; Francischi, JN; Pacheco, DF; Perez, AC; Reis, GM | 1 |
da Fonseca Pacheco, CM; da Fonseca Pacheco, D; de Castro Perez, A; de Francischi, JN; Duarte, ID; Klein, A | 1 |
Brandt, MR; Furness, MS; Mello, NK; Negus, SS; Rice, KC | 1 |
19 other study(ies) available for 4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide and Allodynia
Article | Year |
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Forebrain delta opioid receptors regulate the response of delta agonist in models of migraine and opioid-induced hyperalgesia.
Topics: Analgesics, Opioid; Animals; Benzamides; Cortical Spreading Depression; Disease Models, Animal; GABAergic Neurons; Hyperalgesia; Mice; Mice, Knockout; Migraine Disorders; Nitroglycerin; Piperazines; Prosencephalon; Receptors, Opioid, delta | 2020 |
The induction of the transcription factor Nrf2 enhances the antinociceptive effects of delta-opioid receptors in diabetic mice.
Topics: Animals; Benzamides; Blood Glucose; Blotting, Western; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Enkephalin, D-Penicillamine (2,5)-; Hyperalgesia; Isothiocyanates; Male; Mice; NF-E2-Related Factor 2; Piperazines; Receptors, Opioid, delta; Sulfoxides | 2017 |
Role of signalling molecules in behaviours mediated by the δ opioid receptor agonist SNC80.
Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Arrestins; Behavior, Animal; Benzamides; Disease Models, Animal; Female; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Piperazines; Receptors, Opioid, delta; Seizures; Signal Transduction; Swimming | 2018 |
Delta opioid receptor agonists are effective for multiple types of headache disorders.
Topics: Animals; Benzamides; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Headache Disorders; Hyperalgesia; Male; Mice; Morphine; Nitroglycerin; Piperazines; Receptors, Opioid, delta; Sumatriptan | 2019 |
Chronic inflammatory injury results in increased coupling of delta opioid receptors to voltage-gated Ca2+ channels.
Topics: Animals; Arrestins; Benzamides; beta-Arrestin 2; beta-Arrestins; Calcium Channels; Chronic Disease; Chronic Pain; Freund's Adjuvant; Ganglia, Spinal; Hyperalgesia; Inflammation; Ion Channel Gating; Mice; Mice, Knockout; Pain Threshold; Piperazines; Receptors, Opioid, delta | 2013 |
Differential effects of opioid-related ligands and NSAIDs in nonhuman primate models of acute and inflammatory pain.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acute Pain; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fentanyl; Hyperalgesia; Imidazoles; Inflammation; Macaca; Male; Nociceptive Pain; Pain Measurement; Piperazines; Receptors, Opioid; Spiro Compounds | 2014 |
δ-Opioid receptor agonists inhibit migraine-related hyperalgesia, aversive state and cortical spreading depression in mice.
Topics: Animals; Avoidance Learning; Benzamides; Cortical Spreading Depression; Female; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Migraine Disorders; Nitroglycerin; Piperazines; Receptors, Opioid, delta | 2014 |
In vivo properties of KNT-127, a novel δ opioid receptor agonist: receptor internalization, antihyperalgesia and antidepressant effects in mice.
Topics: Analgesics; Animals; Antidepressive Agents; Behavior, Animal; Benzamides; Depression; Drug Tolerance; Freund's Adjuvant; Hot Temperature; Hyperalgesia; Male; Mice, Inbred C57BL; Mice, Knockout; Morphinans; Motor Activity; Pain; Piperazines; Receptors, Opioid, delta | 2014 |
β-arrestin-2-biased agonism of delta opioid receptors sensitizes transient receptor potential vanilloid type 1 (TRPV1) in primary sensory neurons.
Topics: Animals; Arrestins; Benzamides; beta-Arrestin 2; beta-Arrestins; Capsaicin; Cells, Cultured; Disease Models, Animal; Hyperalgesia; Lectins; Male; Mice; Mice, Inbred C57BL; Pain Threshold; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Sensory Receptor Cells; Sensory System Agents; Species Specificity; Time Factors; Trigeminal Ganglion; TRPV Cation Channels | 2014 |
Agonist-Specific Recruitment of Arrestin Isoforms Differentially Modify Delta Opioid Receptor Function.
Topics: Animals; Arrestins; Benzamides; Drug Tolerance; Female; Hyperalgesia; Male; Mice; Mice, Knockout; Pain Perception; Piperazines; Protein Isoforms; Receptors, Opioid, delta | 2016 |
The role of regulator of G protein signaling 4 in delta-opioid receptor-mediated behaviors.
Topics: Animals; Antidepressive Agents; Benzamides; Corpus Striatum; Hyperalgesia; Male; Mice; Mice, Knockout; Phosphorylation; Piperazines; Receptors, Opioid, delta; RGS Proteins; Signal Transduction; Swimming | 2017 |
Inflammatory pain is enhanced in delta opioid receptor-knockout mice.
Topics: Analgesics, Opioid; Animals; Benzamides; Brain; Female; Freund's Adjuvant; Hyperalgesia; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Nociceptors; Pain; Piperazines; Receptors, Opioid, delta | 2008 |
Cholecystokinin receptors mediate tolerance to the analgesic effect of TENS in arthritic rats.
Topics: Analgesics, Opioid; Animals; Arthritis, Experimental; Benzamides; Biophysics; Carrageenan; Cholecystokinin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Hyperalgesia; Kaolin; Knee Joint; Male; Pain Measurement; Pain Threshold; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Statistics, Nonparametric; Transcutaneous Electric Nerve Stimulation | 2010 |
Ligand-directed trafficking of the δ-opioid receptor in vivo: two paths toward analgesic tolerance.
Topics: Analgesics; Animals; Benzamides; Brain; Calcium; Cell Membrane; Disease Models, Animal; Drug Interactions; Drug Tolerance; Female; Freund's Adjuvant; Ganglia, Spinal; Green Fluorescent Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hyperalgesia; Inflammation; Ligands; Locomotion; Male; Maze Learning; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pain; Pain Threshold; Patch-Clamp Techniques; Piperazines; Piperidines; Protein Binding; Protein Transport; Receptors, Opioid, delta; Sensory Receptor Cells; Spinal Cord; Statistics, Nonparametric; Sulfur Isotopes; Time Factors | 2010 |
Chronic muscle pain induced by repeated acid Injection is reversed by spinally administered mu- and delta-, but not kappa-, opioid receptor agonists.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Behavior, Animal; Benzamides; Chronic Disease; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Hydrochloric Acid; Hydrogen-Ion Concentration; Hyperalgesia; Injections, Spinal; Morphine; Muscular Diseases; Pain Threshold; Physical Stimulation; Piperazines; Rats; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2002 |
A comparison of the antinociceptive and adverse effects of the mu-opioid agonist morphine and the delta-opioid agonist SNC80.
Topics: Animals; Benzamides; Carbon Dioxide; Discrimination Learning; Hyperalgesia; Male; Morphine; Motor Activity; Pain; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu | 2005 |
delta-Opioid receptor agonist SNC80 elicits peripheral antinociception via delta(1) and delta(2) receptors and activation of the l-arginine/nitric oxide/cyclic GMP pathway.
Topics: Analgesics; Animals; Arginine; Benzamides; Benzylidene Compounds; Cyclic GMP; Dinoprostone; Enzyme Inhibitors; Hyperalgesia; Male; Naltrexone; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Piperazines; Rats; Receptors, Opioid, delta | 2005 |
The mu-opioid receptor agonist morphine, but not agonists at delta- or kappa-opioid receptors, induces peripheral antinociception mediated by cannabinoid receptors.
Topics: Amidohydrolases; Analgesics, Opioid; Animals; Arachidonic Acids; Benzamides; Benzomorphans; Cannabinoid Receptor Modulators; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hyperalgesia; Indoles; Male; Morphine; Organophosphonates; Pain; Pain Measurement; Piperazines; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2008 |
Antinociceptive effects of delta-opioid agonists in Rhesus monkeys: effects on chemically induced thermal hypersensitivity.
Topics: Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Capsaicin; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Freund's Adjuvant; Hyperalgesia; Ketorolac; Macaca mulatta; Male; Morphine; Pain; Pain Measurement; Piperazines; Receptors, Opioid, delta | 2001 |