4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol has been researched along with Dementia Praecox in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (11.54) | 18.7374 |
| 1990's | 20 (76.92) | 18.2507 |
| 2000's | 3 (11.54) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Furukori, H; Inoue, Y; Kaneko, S; Kondo, T; Mihara, K; Otani, K; Suzuki, A; Yasui-Furukori, N | 1 |
| Hamachi, C; Imamura, Y; Kishikawa, N; Kuroda, N; Nakashima, K; Ohba, Y; Tagawa, Y | 1 |
| Costakos, DT; Kleinman, JE; Korpi, ER; Linnoila, M; Wyatt, RJ | 1 |
| Knorr, W; Meyer, FP; Neuhof, S; Ulrich, S | 1 |
| Eyles, DW; Pond, SM; Stedman, TJ | 1 |
| Chang, WH; Chien, CP; Jann, MW; Liu, HC; Shieh, YS | 1 |
| Aravagiri, M; Marder, SR; Marshall, BD; Van Putten, T | 1 |
| Chang, WH; Chen, LC; Chien, CP; Hu, WH; Jann, MW; Juang, DJ; Lam, YF; Lin, SK; Yang, CH | 1 |
| Chang, WH; Chen, LC; Chien, CP; Hu, WH; Jann, MW; Juang, DJ; Lam, YW; Lin, SK; Yang, CH | 1 |
| Chang, WH; Chiang, TS; Chien, CP; Hu, WH; Jann, MW; Lin, HN | 1 |
| Carter, JG; Crabtree, BL; Jann, MW; Lam, YW; Pitts, WM | 1 |
| Chang, WH; Chang, YC; Hu, OY; Hu, WH; Jann, MW; Lane, HY; Lin, HN | 1 |
| Han, CS; Kim, SH; Lee, MS; You, YW | 1 |
| Braun, V; Meyer, FP; Neuhof, S; Ulrich, S | 1 |
| Belpaire, FM; Berlo, JA; De Schepper, N; Pan, L; Rosseel, MT; Vander Stichele, R | 1 |
| Furukori, H; Inoue, Y; Kaneko, S; Kondo, T; Mihara, K; Nagashima, U; Ono, S; Otani, K; Suzuki, A; Yasui, N | 1 |
| Gaertner, HJ; Mahal, A; Stevens, A | 1 |
| Hasegawa, K; Hirayama, H; Matsuno, H; Nakashima, M; Sato, H; Uematsu, T | 1 |
| Gaertner, HJ; Mahal, A; Stevens, A; Stevens, I | 1 |
| Chang, WH | 1 |
| Cooper, TB; Czobor, P; Volavka, J | 1 |
| Chang, WH; Chen, H; Jann, MW; Lam, YW | 1 |
| Chang, WH; Chen, H; Chen, TY; Chien, CP; Davis, CM; Hwu, HG; Jann, MW; Lam, YW; Lin, HN; Lin, SK | 1 |
| Chang, WH; Jann, MW; Lin, SK | 1 |
| Chang, WH; Chen, TY; Hu, WH; Lee, CF; Yeh, EK | 1 |
| Browning, JL; Davis, CM; Harrington, CA | 1 |
1 review(s) available for 4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol and Dementia Praecox
| Article | Year |
|---|---|
Reduced haloperidol: a factor in determining the therapeutic benefit of haloperidol treatment?
Topics: Animals; Haloperidol; Humans; Schizophrenia | 1992 |
10 trial(s) available for 4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol and Dementia Praecox
| Article | Year |
|---|---|
Histamine H1-receptor antagonists, promethazine and homochlorcyclizine, increase the steady-state plasma concentrations of haloperidol and reduced haloperidol.
Topics: Adult; Aged; Antipsychotic Agents; Cyclizine; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Female; Haloperidol; Histamine H1 Antagonists; Humans; Male; Middle Aged; Promethazine; Schizophrenia | 2003 |
Megabore capillary gas-liquid chromatographic method with nitrogen-phosphorus selective detection for the assay of haloperidol and reduced haloperidol in serum: results of therapeutic drug-monitoring during acute therapy of eight schizophrenics.
Topics: Adult; Chromatography, Gas; Drug Monitoring; Female; Haloperidol; Humans; Male; Middle Aged; Schizophrenia | 1995 |
Nonlinear relationship between circulating concentrations of reduced haloperidol and haloperidol: evaluation of possible mechanisms.
Topics: Adolescent; Adult; Aged; Blood Proteins; Chronic Disease; Cytosol; Erythrocytes; Female; Haloperidol; Humans; Hydrogen-Ion Concentration; Ketone Oxidoreductases; Liver; Male; Microsomes, Liver; Middle Aged; Protein Binding; Schizophrenia; Stereoisomerism | 1994 |
Plasma reduced haloperidol/haloperidol ratios in schizophrenic patients treated with high dosages of haloperidol.
Topics: Adult; Chronic Disease; Dose-Response Relationship, Drug; Drug Resistance; Haloperidol; Humans; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia | 1994 |
Simultaneous determination of plasma haloperidol and its metabolite reduced haloperidol by liquid chromatography with electrochemical detection. Plasma levels in schizophrenic patients treated with oral or intramuscular depot haloperidol.
Topics: Administration, Oral; Chromatography, Liquid; Delayed-Action Preparations; Drug Resistance; Electrochemistry; Haloperidol; Humans; Injections, Intramuscular; Schizophrenia | 1994 |
Plasma alpha-one acid glycoprotein and haloperidol concentrations in schizophrenic patients.
Topics: Adult; Antipsychotic Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Male; Middle Aged; Neurologic Examination; Orosomucoid; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology | 1997 |
Co-administration of sertraline and haloperidol.
Topics: Adult; Aged; Antidepressive Agents; Antipsychotic Agents; Drug Interactions; Drug Therapy, Combination; Female; Haloperidol; Humans; Male; Metabolic Clearance Rate; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia; Sertraline | 1998 |
Reduced haloperidol does not interfere with the antipsychotic activity of haloperidol in the treatment of acute schizophrenia.
Topics: Acute Disease; Adult; Antipsychotic Agents; Basal Ganglia Diseases; Dose-Response Relationship, Drug; Drug Interactions; Female; Haloperidol; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia | 1999 |
Haloperidol and lorazepam combined: clinical effects and drug plasma levels in the treatment of acute schizophrenic psychosis.
Topics: Acute Disease; Adult; Drug Therapy, Combination; Female; Haloperidol; Humans; Lorazepam; Male; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology | 1992 |
Plasma drug level and clinical response.
Topics: Chronic Disease; Dose-Response Relationship, Drug; Haloperidol; Humans; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology | 1992 |
15 other study(ies) available for 4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol and Dementia Praecox
| Article | Year |
|---|---|
Determination of haloperidol and reduced haloperidol in human serum by liquid chromatography after fluorescence labeling based on the Suzuki coupling reaction.
Topics: Boron Compounds; Chromatography, High Pressure Liquid; Drug Monitoring; Female; Fluorescence; Haloperidol; Humans; Male; Molecular Structure; Oxidation-Reduction; Reference Values; Reproducibility of Results; Schizophrenia; Sensitivity and Specificity | 2006 |
Reduced haloperidol in the post-mortem brains of haloperidol-treated patients.
Topics: Adult; Animals; Brain Chemistry; Cerebellum; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Corpus Striatum; Female; Haloperidol; Humans; Liver; Male; Middle Aged; Occipital Lobe; Rats; Rats, Inbred Strains; Schizophrenia | 1984 |
Reduced haloperidol/haloperidol ratios after oral haloperidol and decanoate administration in schizophrenics.
Topics: Administration, Oral; Adult; Chromatography, High Pressure Liquid; Female; Haloperidol; Humans; Male; Middle Aged; Regression Analysis; Schizophrenia | 1993 |
Prolonged haloperidol and reduced haloperidol plasma concentrations after decanoate withdrawal.
Topics: Adult; Female; Half-Life; Haloperidol; Humans; Injections, Intramuscular; Male; Metabolic Clearance Rate; Middle Aged; Schizophrenia; Schizophrenic Psychology; Substance Withdrawal Syndrome | 1993 |
Plasma haloperidol and reduced haloperidol concentrations in a geriatric population.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antipsychotic Agents; Bipolar Disorder; Dementia; Dose-Response Relationship, Drug; Female; Haloperidol; Humans; Male; Metabolic Clearance Rate; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology | 1996 |
Dose-dependent reduced haloperidol/haloperidol ratios: influence of patient-related variables.
Topics: Adult; Age Factors; Antipsychotic Agents; Body Weight; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Male; Metabolic Clearance Rate; Middle Aged; Schizophrenia; Sex Factors | 1997 |
Effects of smoking, CYP2D6 genotype, and concomitant drug intake on the steady state plasma concentrations of haloperidol and reduced haloperidol in schizophrenic inpatients.
Topics: Adult; Aged; Antipsychotic Agents; Cytochrome P-450 CYP2D6; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Enzyme Induction; Enzyme Inhibitors; Genotype; Haloperidol; Humans; Inpatients; Middle Aged; Polymorphism, Genetic; Polypharmacy; Schizophrenia; Smoking | 1999 |
Effect of a genetic polymorphism of CYP1A2 inducibility on the steady state plasma concentrations of haloperidol and reduced haloperidol in Japanese patients with schizophrenia.
Topics: Alleles; Antipsychotic Agents; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Enzyme Induction; Female; Genotype; Haloperidol; Humans; Male; Middle Aged; Point Mutation; Polymorphism, Genetic; Schizophrenia; Smoking | 2000 |
Haloperidol and reduced haloperidol serum levels: correlation with psychopathology in acute schizophrenia.
Topics: Adult; Chromatography, High Pressure Liquid; Haloperidol; Humans; Middle Aged; Psychiatric Status Rating Scales; Regression Analysis; Schizophrenia; Schizophrenic Psychology | 1992 |
Steady-state pharmacokinetics of haloperidol and reduced haloperidol in schizophrenic patients: analysis of factors determining their concentrations in hair.
Topics: Administration, Oral; Adult; Aged; Chromatography, High Pressure Liquid; Female; Hair; Haloperidol; Humans; Male; Middle Aged; Schizophrenia | 1992 |
Pharmacokinetics of haloperidol and reduced haloperidol in Chinese schizophrenic patients after intravenous and oral administration of haloperidol.
Topics: Administration, Oral; Adult; Biological Availability; China; Chromatography, High Pressure Liquid; Half-Life; Haloperidol; Humans; Injections, Intravenous; Male; Middle Aged; Models, Biological; Schizophrenia | 1992 |
Comparison of haloperidol and reduced haloperidol plasma levels in four different ethnic populations.
Topics: Black or African American; Black People; China; Chromatography, Liquid; Ethnicity; Haloperidol; Hispanic or Latino; Humans; Psychiatric Status Rating Scales; Radioimmunoassay; Schizophrenia; United States; White People | 1992 |
Interconversions between haloperidol and reduced haloperidol in schizophrenic patients and guinea pigs: a steady-state study.
Topics: Adult; Animals; Biotransformation; Corpus Striatum; Dose-Response Relationship, Drug; Guinea Pigs; Haloperidol; Humans; Male; Middle Aged; Schizophrenia; Schizophrenic Psychology | 1991 |
Low plasma reduced haloperidol/haloperidol ratios in Chinese patients.
Topics: China; Ethnicity; Female; Haloperidol; Humans; Male; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology | 1987 |
Quantification of reduced haloperidol and haloperidol by radioimmunoassay.
Topics: Chromatography, Liquid; Cross Reactions; Haloperidol; Humans; Radioimmunoassay; Schizophrenia | 1985 |