4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic-acid has been researched along with Pain* in 1 studies
1 other study(ies) available for 4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic-acid and Pain
| Article | Year |
|---|---|
Synthesis and biological evaluation of new series of benzamide derivatives containing urea moiety as sEH inhibitors.
The pharmacological inhibition of soluble epoxide hydrolase (sEH) was shown to reduce inflammation and pain. Herein, we described a series of newly synthesized sEH inhibitors with the trident-shaped skeleton. Intensive structural modifications led to the identification of compound B15 as a potent sEH inhibitor with an IC Topics: Animals; Benzamides; Enzyme Inhibitors; Epoxide Hydrolases; Pain; Rats; Structure-Activity Relationship; Urea | 2022 |