4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone has been researched along with Substance Withdrawal Syndrome in 5 studies
4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone: Inhibitor of phosphodiesterases.
Substance Withdrawal Syndrome: Physiological and psychological symptoms associated with withdrawal from the use of a drug after prolonged administration or habituation. The concept includes withdrawal from smoking or drinking, as well as withdrawal from an administered drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adenosine A1 receptors were not desensitized, because the potency of the metabolically stable adenosine analog N6-cyclopentyl-adenosine was unchanged after chronic cocaine withdrawal." | 1.30 | Decreased presynaptic sensitivity to adenosine after cocaine withdrawal. ( Bockaert, J; Manzoni, O; Pujalte, D; Williams, J, 1998) |
| " The naltrexone stimulus-generalization curve and dose-response curve for loss of body weight were shifted to the left by IBMX and Ro 20-1724, which produce quasi-withdrawal, but not by papaverine, which does not." | 1.28 | Phosphodiesterase inhibitors potentiate opiate-antagonist discrimination by morphine-dependent rats. ( Holtzman, SG, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Collier, HO | 2 |
| Cuthbert, NJ | 1 |
| Francis, DL | 2 |
| Manzoni, O | 1 |
| Pujalte, D | 1 |
| Williams, J | 1 |
| Bockaert, J | 1 |
| Kaplan, GB | 1 |
| Coyle, TS | 1 |
| Roy, AC | 1 |
| Holtzman, SG | 1 |
5 other studies available for 4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone and Substance Withdrawal Syndrome
| Article | Year |
|---|---|
Character and meaning of quasi-morphine withdrawal phenomena elicited by methylxanthines.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Caffeine; Huma | 1981 |
Decreased presynaptic sensitivity to adenosine after cocaine withdrawal.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Affinity Labels; Animals; Cocaine; Dipyri | 1998 |
Adenosine kinase inhibitors attenuate opiate withdrawal via adenosine receptor activation.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine Kinase; Animals; Body Weight; Caffeine; De | 1998 |
Morphone abstinence and quasi-abstinence effects after phosphodiesterase inhibitors and naloxone.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Caffei | 1975 |
Phosphodiesterase inhibitors potentiate opiate-antagonist discrimination by morphine-dependent rats.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Body Weight; D | 1989 |