4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone has been researched along with Muscle Relaxation in 10 studies
4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone: Inhibitor of phosphodiesterases.
Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chlorogenic acid (CGA) is a polyphenol found in coffee and medicinal herbs such as Lonicera japonica." | 1.48 | Effects of chlorogenic acid on carbachol-induced contraction of mouse urinary bladder. ( Kaneda, T; Sasaki, N; Shimizu, K; Urakawa, N, 2018) |
| "Rolipram caused an increase in the frequency of Ca(2+) sparks and the spontaneous transient BK currents (TBKCs), hyperpolarized the cell membrane potential (MP), and decreased the intracellular Ca(2+) levels." | 1.40 | BK channel-mediated relaxation of urinary bladder smooth muscle: a novel paradigm for phosphodiesterase type 4 regulation of bladder function. ( Cheng, Q; Li, N; Petkov, GV; Xin, W, 2014) |
| " Among them, 3,4-dipropyl-4,5,7,8-tetrahydro-3H-imidazo[1,2-i]-purin-5-one (1c), which was the most selective and potent PDE IV inhibitor, did not cause emesis in Suncus murinus at a dosage range of 10-100 mg/kg (po), while an imidazole analogue of 1c (4c) and known PDE IV inhibitors such as rolipram and denbufylline caused emesis even at 10 or 30 mg/kg." | 1.30 | Selective inhibitors of cyclic AMP-specific phosphodiesterase: heterocycle-condensed purines. ( Kasugai, S; Miyamoto, K; Ohya, K; Sawanishi, H; Suzuki, H; Suzuki, N; Takagi, K; Waki, Y; Yamamoto, S, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sawanishi, H | 1 |
| Suzuki, H | 1 |
| Yamamoto, S | 1 |
| Waki, Y | 1 |
| Kasugai, S | 1 |
| Ohya, K | 1 |
| Suzuki, N | 1 |
| Miyamoto, K | 1 |
| Takagi, K | 1 |
| Kaneda, T | 1 |
| Sasaki, N | 1 |
| Urakawa, N | 1 |
| Shimizu, K | 1 |
| Xin, W | 1 |
| Li, N | 1 |
| Cheng, Q | 1 |
| Petkov, GV | 1 |
| Birowo, P | 1 |
| Uckert, S | 1 |
| Kedia, GT | 1 |
| Sonnenberg, JE | 1 |
| Sandner, P | 1 |
| Thon, WF | 1 |
| Scheller, F | 1 |
| Rahardjo, D | 1 |
| Kuczyk, MA | 1 |
| Larsen, GL | 1 |
| Loader, JE | 1 |
| Fratelli, C | 1 |
| Brian Kang, JK | 1 |
| Dakhama, A | 1 |
| Colasurdo, GN | 1 |
| Meisheri, KD | 1 |
| van Breemen, C | 2 |
| Planquois, JM | 1 |
| Ruffin-Morin, Y | 1 |
| Lagente, V | 1 |
| Payne, AN | 1 |
| Dahl, SG | 1 |
| Bültmann, R | 1 |
| Klebroff, W | 1 |
| Starke, K | 1 |
| Mueller, E | 1 |
| Tsujimoto, G | 1 |
| Lee, CH | 1 |
| Hoffman, BB | 1 |
10 other studies available for 4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone and Muscle Relaxation
| Article | Year |
|---|---|
Selective inhibitors of cyclic AMP-specific phosphodiesterase: heterocycle-condensed purines.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Administration, Oral; Animals; Cyclic Nucleotide Phosphodiester | 1997 |
Effects of chlorogenic acid on carbachol-induced contraction of mouse urinary bladder.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenylyl Cyclases; Anim | 2018 |
BK channel-mediated relaxation of urinary bladder smooth muscle: a novel paradigm for phosphodiesterase type 4 regulation of bladder function.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Calcium; Calcium Signaling; Cell Polarity; | 2014 |
Exposure of human seminal vesicle tissue to phosphodiesterase (PDE) inhibitors antagonizes the contraction induced by norepinephrine and increases production of cyclic nucleotides.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Aged; Colforsin; Cyclic AMP; Cyclic GMP; Drug Evalua | 2010 |
Phosphodiesterase IV and neutral endopeptidase in airways from developing and allergen sensitized rabbits.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Age Factors; Al | 2006 |
Effects of beta-adrenergic stimulation on calcium movements in rabbit aortic smooth muscle: relationship with cyclic AMP.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Aorta; Biological Transport; Bucladesine; C | 1982 |
Salbutamol potentiates the relaxant effects of selective phosphodiesterase inhibitors on guinea pig isolated trachea.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adrenergic beta-Agonists; Albuterol; Animals; Drug S | 1996 |
Nucleotide-evoked relaxation of rat vas deferens: possible mechanisms.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Diphosphate; Adenosine Triphosp | 2002 |
Role of intracellular Ca2+ sequestration in beta-adrenergic relaxation of a smooth muscle.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Calcium; Cyclic AMP; Isoproterenol; Muscle | 1979 |
Age-related decrease in beta adrenergic receptor-mediated vascular smooth muscle relaxation.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Acetylcholine; Aging; B | 1986 |