4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone has been researched along with Bronchial Hyperreactivity in 3 studies
4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone: Inhibitor of phosphodiesterases.
Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.
| Excerpt | Relevance | Reference |
|---|---|---|
| ") administered 30 min before and 6 h after antigen challenge (double dosing regimen), did not affect the development of the early or late phase responses." | 1.30 | Effects of inhibitors of phosphodiesterase, on antigen-induced bronchial hyperreactivity in conscious sensitized guinea-pigs and airway leukocyte infiltration. ( Broadley, KJ; Danahay, H, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Danahay, H | 2 |
| Broadley, KJ | 2 |
| Ikemura, T | 1 |
| Schwarze, J | 1 |
| Makela, M | 1 |
| Kanehiro, A | 1 |
| Joetham, A | 1 |
| Ohmori, K | 1 |
| Gelfand, EW | 1 |
3 other studies available for 4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone and Bronchial Hyperreactivity
| Article | Year |
|---|---|
Effects of inhibitors of phosphodiesterase, on antigen-induced bronchial hyperreactivity in conscious sensitized guinea-pigs and airway leukocyte infiltration.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4-(3-Butoxy-4-methoxybenzyl)-2-i | 1997 |
PDE4 inhibition and a corticosteroid in chronically antigen exposed conscious guinea-pigs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3',5'-Cyclic-AMP Phosphodiestera | 1998 |
Type 4 phosphodiesterase inhibitors attenuate respiratory syncytial virus-induced airway hyper-responsiveness and lung eosinophilia.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Bronch | 2000 |