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4-(2-chlorophenyl)-2-(2-(4-isobutylphenyl)ethyl)-6,9-dimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine and Asthma, Bronchial

4-(2-chlorophenyl)-2-(2-(4-isobutylphenyl)ethyl)-6,9-dimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine has been researched along with Asthma, Bronchial in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Haruta, Y; Hozawa, S; Ishioka, S; Yamakido, M1
Fujimura, M; Matsuda, T; Ogawa, H; Saito, M2
Fujimura, M; Matsuda, T; Myou, S; Songür, N; Tsujiura, M1
Fukuda, T; Makino, S; Sagara, H1
Iwahisa, Y; Kagoshima, M; Kawakami, Y; Terasawa, M; Tomomatsu, N; Yamaguchi, S1
Iwahisa, Y; Kagoshima, M; Kawakami, Y; Matsuura, M; Terasawa, M; Tomomatsu, N; Yamaguchi, S1
Kagoshima, M; Kohge, S; Terasawa, M; Yamaguchi, S1
Akiyama, Y; Iwane, S; Komatsu, H; Mizuki, M; Tsuda, T1
Katayama, K; Katayama, S; Sakuma, Y; Shirato, M; Tsunoda, H; Yamatsu, I1
Harada, K; Katayama, K; Katayama, S; Muramoto, K; Sakuma, Y; Tsunoda, H1

Reviews

1 review(s) available for 4-(2-chlorophenyl)-2-(2-(4-isobutylphenyl)ethyl)-6,9-dimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine and Asthma, Bronchial

ArticleYear
[PAF receptor antagonist in asthma therapy].
    Nihon rinsho. Japanese journal of clinical medicine, 1996, Volume: 54, Issue:11

    Topics: Animals; Asthma; Azepines; Humans; Platelet Activating Factor; Triazoles

1996

Trials

1 trial(s) available for 4-(2-chlorophenyl)-2-(2-(4-isobutylphenyl)ethyl)-6,9-dimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine and Asthma, Bronchial

ArticleYear
Effects of a PAF antagonist, Y-24180, on bronchial hyperresponsiveness in patients with asthma.
    American journal of respiratory and critical care medicine, 1995, Volume: 152, Issue:4 Pt 1

    Topics: Adult; Analysis of Variance; Asthma; Azepines; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Cross-Over Studies; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Platelet Activating Factor; Platelet Aggregation Inhibitors; Triazoles

1995

Other Studies

9 other study(ies) available for 4-(2-chlorophenyl)-2-(2-(4-isobutylphenyl)ethyl)-6,9-dimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine and Asthma, Bronchial

ArticleYear
Role of thromboxane A2 and platelet-activating factor in allergic bronchoconstriction in guinea pig airway in vivo.
    Journal of lipid mediators and cell signalling, 1995, Volume: 11, Issue:1

    Topics: Administration, Inhalation; Animals; Antigens; Asthma; Azepines; Bridged Bicyclo Compounds; Bronchoconstriction; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Guinea Pigs; Hypersensitivity; Male; Platelet Activating Factor; Receptors, Prostaglandin; Thromboxane A2; Triazoles

1995
Role of leukotrienes and platelet activating factor in allergic bronchoconstriction and their interactions in guinea pig airway in vivo.
    Prostaglandins, leukotrienes, and essential fatty acids, 1993, Volume: 49, Issue:2

    Topics: Animals; Asthma; Azepines; Bronchoconstriction; Bronchodilator Agents; Guinea Pigs; Leukotriene Antagonists; Leukotrienes; Male; Platelet Activating Factor; Pyridines; Pyrimidinones; Respiratory Hypersensitivity; Tetrazoles; Triazoles

1993
Involvement of PAF in postallergic propranolol-induced bronchoconstriction in guinea-pigs.
    The European respiratory journal, 1996, Volume: 9, Issue:10

    Topics: Administration, Inhalation; Adrenergic beta-Antagonists; Anesthesia, General; Animals; Antigens; Asthma; Azepines; Bronchoconstriction; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Hypersensitivity; Immunization; Inflammation Mediators; Injections, Intravenous; Male; Platelet Activating Factor; Propranolol; Respiration, Artificial; Time Factors; Triazoles

1996
Effects of Y-24180, a long-acting and potent antagonist to platelet-activating factor, on immediate asthmatic response in guinea pigs.
    Pharmacology, 1997, Volume: 54, Issue:1

    Topics: Animals; Anti-Asthmatic Agents; Asthma; Azepines; Benzoquinones; Bronchodilator Agents; Chromones; Drug Interactions; Drug Therapy, Combination; Guinea Pigs; Heptanoic Acids; Male; Methacrylates; Platelet Activating Factor; Theophylline; Triazoles

1997
Suppressive effects of Y-24180, a receptor antagonist to platelet activating factor (PAF), on antigen-induced asthmatic responses in guinea pigs.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1997, Volume: 46, Issue:4

    Topics: Administration, Oral; Aerosols; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Azepines; Benzoquinones; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchodilator Agents; Chromones; Enzyme Inhibitors; Guinea Pigs; Heptanoic Acids; Histamine Antagonists; Leukotriene Antagonists; Male; Methacrylates; Ovalbumin; Platelet Membrane Glycoproteins; Pyrilamine; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serine Proteinase Inhibitors; Signal Transduction; Theophylline; Thromboxane-A Synthase; Triazoles

1997
Suppressive effects of Y-24180, a long-acting antagonist for platelet-activating factor, on allergic pulmonary eosinophilia in mice.
    Japanese journal of pharmacology, 1997, Volume: 75, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Asthma; Azepines; Bronchoalveolar Lavage Fluid; Eosinophils; Interleukin-5; Lung; Male; Mice; Mice, Inbred BALB C; Platelet Aggregation Inhibitors; Prednisolone; Pulmonary Eosinophilia; Triazoles

1997
Inhibition of eosinophil activation in bronchoalveolar lavage fluid from atopic asthmatics by Y-24180, an antagonist to platelet-activating factor.
    Life sciences, 1999, Volume: 65, Issue:20

    Topics: Adult; Antigens, CD; Asthma; Azepines; Blood Proteins; Bronchi; Bronchoalveolar Lavage Fluid; Eosinophil Granule Proteins; Eosinophils; Female; Fibronectins; Humans; Integrin alpha1; Intercellular Adhesion Molecule-1; Leukocyte Count; Macrophage-1 Antigen; Male; Middle Aged; Platelet Activating Factor; Ribonucleases; Triazoles

1999
Pharmacological effects of oral E6123, a novel PAF antagonist, on biological changes induced by PAF inhalation in guinea pigs.
    Prostaglandins, 1991, Volume: 42, Issue:5

    Topics: Administration, Oral; Analysis of Variance; Animals; Asthma; Azepines; Bronchial Hyperreactivity; Bronchoconstriction; Calcium; Eosinophils; Guinea Pigs; Lung; Male; Platelet Activating Factor; Triazoles

1991
Inhibitory effects of a novel PAF antagonist E6123 on anaphylactic responses in passively and actively sensitized guinea pigs and passively sensitized mice.
    Prostaglandins, 1991, Volume: 42, Issue:6

    Topics: Administration, Inhalation; Anaphylaxis; Animals; Antigens; Asthma; Azepines; Guinea Pigs; Male; Mice; Mice, Inbred ICR; Ovalbumin; Platelet Activating Factor; Propranolol; Pyrilamine; Triazoles

1991