Page last updated: 2024-10-21

4-(2-aminoethyl)benzenesulfonylfluoride and Melanoma

4-(2-aminoethyl)benzenesulfonylfluoride has been researched along with Melanoma in 2 studies

Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)

Research Excerpts

ExcerptRelevanceReference
"In the present study, we have investigated the influence of telomerase inhibition in chemosensitivity of melanoma cells to temozolomide (TMZ), a methylating agent with promising antitumor activity against metastatic melanoma."7.72Inhibition of telomerase increases resistance of melanoma cells to temozolomide, but not to temozolomide combined with poly (adp-ribose) polymerase inhibitor. ( Balduzzi, A; Barbarino, M; Biroccio, A; Gold, B; Graziani, G; Levati, L; Lombardi, ML; Portarena, I; Tentori, L; Vergati, M, 2003)
"In the present study, we have investigated the influence of telomerase inhibition in chemosensitivity of melanoma cells to temozolomide (TMZ), a methylating agent with promising antitumor activity against metastatic melanoma."3.72Inhibition of telomerase increases resistance of melanoma cells to temozolomide, but not to temozolomide combined with poly (adp-ribose) polymerase inhibitor. ( Balduzzi, A; Barbarino, M; Biroccio, A; Gold, B; Graziani, G; Levati, L; Lombardi, ML; Portarena, I; Tentori, L; Vergati, M, 2003)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tentori, L1
Portarena, I1
Barbarino, M1
Balduzzi, A1
Levati, L1
Vergati, M1
Biroccio, A1
Gold, B1
Lombardi, ML1
Graziani, G1
Ahrens, T1
Sleeman, JP1
Schempp, CM1
Howells, N1
Hofmann, M1
Ponta, H1
Herrlich, P1
Simon, JC1

Other Studies

2 other studies available for 4-(2-aminoethyl)benzenesulfonylfluoride and Melanoma

ArticleYear
Inhibition of telomerase increases resistance of melanoma cells to temozolomide, but not to temozolomide combined with poly (adp-ribose) polymerase inhibitor.
    Molecular pharmacology, 2003, Volume: 63, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Carmustine; Cell Division; Dacarbazine; DNA Ligases; Drug Combina

2003
Soluble CD44 inhibits melanoma tumor growth by blocking cell surface CD44 binding to hyaluronic acid.
    Oncogene, 2001, Jun-07, Volume: 20, Issue:26

    Topics: Animals; Binding Sites; Binding, Competitive; Cell Adhesion; Cell Division; Culture Media; Glycopept

2001