4-(2-amino-6-chloro-9h-purin-9-yl)-1,3-dioxolane-2-methanol has been researched along with Melanoma in 1 studies
*Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445) [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Acevedo-Duncan, M; Apostolatos, AH; Ostrov, DA; Ratnayake, WS | 1 |
1 other study(ies) available for 4-(2-amino-6-chloro-9h-purin-9-yl)-1,3-dioxolane-2-methanol and Melanoma
| Article | Year |
|---|---|
Two novel atypical PKC inhibitors; ACPD and DNDA effectively mitigate cell proliferation and epithelial to mesenchymal transition of metastatic melanoma while inducing apoptosis.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Dioxolanes; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Isoenzymes; Melanocytes; Melanoma; Molecular Docking Simulation; Naphthalenes; Neoplasm Metastasis; Protein Kinase C; Purines; RNA, Small Interfering; Signal Transduction; Sulfonic Acids | 2017 |