4-(2-(5-6-7-8-tetrahydro-5-5-8-8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic-acid and Teratoma

4-(2-(5-6-7-8-tetrahydro-5-5-8-8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic-acid has been researched along with Teratoma* in 2 studies

Other Studies

2 other study(ies) available for 4-(2-(5-6-7-8-tetrahydro-5-5-8-8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic-acid and Teratoma

ArticleYear
Induction of mouse totipotent stem cells by a defined chemical cocktail.
    Nature, 2023, Volume: 617, Issue:7962

    In mice, only the zygotes and blastomeres from 2-cell embryos are authentic totipotent stem cells (TotiSCs) capable of producing all the differentiated cells in both embryonic and extraembryonic tissues and forming an entire organism

    Topics: Animals; Blastomeres; Cell Differentiation; Cell Lineage; Embryonic Stem Cells; Mice; Pluripotent Stem Cells; Teratoma; Totipotent Stem Cells

2023
Effects of arotinoids upon murine embryonal carcinoma cells.
    Cancer research, 1983, Volume: 43, Issue:9

    Five arotinoids have been compared with all-trans- and 13-cisretinoic acids for their ability to promote differentiation of cells from murine embryonal carcinoma line Nulli-SCC1. Ro-13-7410, which contains a terminal carboxylic acid residue, and Ro-14-9572, the sodium sulfinate derivative, are potent inducers of differentiation. The sodium sulfonate derivative, Ro-14-3899, is somewhat less active, whereas the ethyl sulfone (Ro-15-1570) and Ro-15-0778, an arotinoid lacking a terminal group, have little or no effect on embryonal carcinoma cell differentiation. Competition by the arotinoids with all-trans-retinoic acid for sites on the cellular retinoic acid-binding protein is qualitatively consistent with their capacity for promoting differentiation. This relationship and the response of differentiation-defective embryonal carcinoma cells to Ro-13-7410 support the view that arotinoids and retinoids promote differentiation of embryonal carcinoma cells via the same mechanism.

    Topics: Animals; Benzoates; Carrier Proteins; Cell Division; Cell Line; Isomerism; Kinetics; Mice; Neoplasm Proteins; Neoplasms, Experimental; Receptors, Retinoic Acid; Retinoids; Structure-Activity Relationship; Teratoma; Tretinoin; Vitamin A

1983