4-((3-(1-6-dihyro-6-oxo-9h-purin-9-yl)-1-oxopropyl)amino)benzoic-acid and Tremor

4-((3-(1-6-dihyro-6-oxo-9h-purin-9-yl)-1-oxopropyl)amino)benzoic-acid has been researched along with Tremor* in 1 studies

Other Studies

1 other study(ies) available for 4-((3-(1-6-dihyro-6-oxo-9h-purin-9-yl)-1-oxopropyl)amino)benzoic-acid and Tremor

Article	Year
Effects of AIT-082, a purine derivative, on tremor induced by arecoline or oxotremorine in mice. Pharmacology, 2007, Volume: 80, Issue:1 The effects of AIT-082, a hypoxanthine derivative, on tremor in mice were investigated. The mice received intragastric administration of AIT-082 for consecutive 60 days at doses of 150, 300 and 600 mg.kg(-1). The results showed that AIT-082 not only effectively inhibited the tremor induced by arecoline or oxotremorine, but also alleviated the tremor intensity and significantly shortened the tremor durations. The inhibition of tremor was perhaps associated with the central cholinergic nerve depressant effects as well as the stimulation of proliferation and differentiation of nerve cells. Topics: Aminobenzoates; Animals; Arecoline; Dose-Response Relationship, Drug; Hypoxanthines; Male; Mice; Mice, Inbred ICR; Muscarinic Agonists; Oxotremorine; Tremor	2007

Article

Year

Effects of AIT-082, a purine derivative, on tremor induced by arecoline or oxotremorine in mice.

Pharmacology, 2007, Volume: 80, Issue:1

The effects of AIT-082, a hypoxanthine derivative, on tremor in mice were investigated. The mice received intragastric administration of AIT-082 for consecutive 60 days at doses of 150, 300 and 600 mg.kg(-1). The results showed that AIT-082 not only effectively inhibited the tremor induced by arecoline or oxotremorine, but also alleviated the tremor intensity and significantly shortened the tremor durations. The inhibition of tremor was perhaps associated with the central cholinergic nerve depressant effects as well as the stimulation of proliferation and differentiation of nerve cells.

Topics: Aminobenzoates; Animals; Arecoline; Dose-Response Relationship, Drug; Hypoxanthines; Male; Mice; Mice, Inbred ICR; Muscarinic Agonists; Oxotremorine; Tremor

2007