4-((2-chloroethyl)(2-mesyloxyethyl)amino)benzoylglutamic acid has been researched along with Cancer of Ovary in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brueggen, J; Friedlos, F; Marais, R; Matter, A; Maycroft, K; O'Reilly, T; Roussel, J; Spooner, RA; Springer, CJ; Stolz, B; Stribbling, SM; Wood, J | 1 |
| Friedlos, F; Marais, R; Schepelmann, S; Spooner, R | 1 |
| Light, Y; Marais, R; Martin, J; Spooner, RA; Springer, CJ | 1 |
| Friedlos, F; Marais, R; Martin, J; Spooner, RA; Springer, CJ | 1 |
4 other study(ies) available for 4-((2-chloroethyl)(2-mesyloxyethyl)amino)benzoylglutamic acid and Cancer of Ovary
| Article | Year |
|---|---|
A novel vascular endothelial growth factor-directed therapy that selectively activates cytotoxic prodrugs.
Topics: Adenocarcinoma; Endothelial Growth Factors; Endothelium; Female; gamma-Glutamyl Hydrolase; Glutamates; Glutamine; Humans; Intercellular Signaling Peptides and Proteins; Lymphokines; Mutagenesis, Site-Directed; Neovascularization, Pathologic; Nitrogen Mustard Compounds; Ovarian Neoplasms; Plasmids; Point Mutation; Prodrugs; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Vascular Endothelial Growth Factors | 2003 |
Methods to improve efficacy in suicide gene therapy approaches: targeting prodrug-activating enzymes carboxypeptidase G2 and nitroreductase to different subcellular compartments.
Topics: Antineoplastic Agents; Aziridines; Bystander Effect; Cell Survival; Female; gamma-Glutamyl Hydrolase; Genes, Transgenic, Suicide; Genetic Therapy; Glutamates; Humans; Nitrogen Mustard Compounds; Nitroreductases; Ovarian Neoplasms; Prodrugs; Subcellular Fractions; Transfection; Tumor Cells, Cultured | 2004 |
Gene-directed enzyme prodrug therapy with a mustard prodrug/carboxypeptidase G2 combination.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Colonic Neoplasms; COS Cells; Drug Screening Assays, Antitumor; Female; gamma-Glutamyl Hydrolase; Genetic Therapy; Genetic Vectors; Gentamicins; Glutamates; Humans; Mutagenesis, Site-Directed; Nitrogen Mustard Compounds; Ovarian Neoplasms; Prodrugs; Transfection; Tumor Cells, Cultured | 1996 |
In suicide gene therapy, the site of subcellular localization of the activating enzyme is more important than the rate at which it activates prodrug.
Topics: Animals; Chlorocebus aethiops; Colorectal Neoplasms; COS Cells; DNA Primers; Electrophoresis, Polyacrylamide Gel; Female; gamma-Glutamyl Hydrolase; Genetic Therapy; Genetic Vectors; Glutamates; Humans; Mutation; Nitrogen Mustard Compounds; Ovarian Neoplasms; Polymerase Chain Reaction; Prodrugs; Tumor Cells, Cultured | 2000 |