Compounds > 4-((2-chloroethyl)(2-mesyloxyethyl)amino)benzoylglutamic acid
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4-((2-chloroethyl)(2-mesyloxyethyl)amino)benzoylglutamic acid and Breast Cancer

4-((2-chloroethyl)(2-mesyloxyethyl)amino)benzoylglutamic acid has been researched along with Breast Cancer in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davies, LC; Friedlos, F; Hedley, D; Martin, J; Ogilvie, LM; Scanlon, IJ; Springer, CJ1
Light, Y; Marais, R; Martin, J; Spooner, RA; Springer, CJ; Stribbling, SM1
Davies, L; Friedlos, F; Marais, R; Martin, J; Spooner, RA; Springer, CJ; Stribbling, SM1

Other Studies

3 other study(ies) available for 4-((2-chloroethyl)(2-mesyloxyethyl)amino)benzoylglutamic acid and Breast Cancer

ArticleYear
Novel fluorinated prodrugs for activation by carboxypeptidase G2 showing good in vivo antitumor activity in gene-directed enzyme prodrug therapy.
    Journal of medicinal chemistry, 2005, Aug-11, Volume: 48, Issue:16

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Fluorine; gamma-Glutamyl Hydrolase; Humans; Mice; Mice, Nude; Mustard Compounds; Neoplasm Transplantation; Prodrugs; Structure-Activity Relationship; Transplantation, Heterologous

2005
A cell surface tethered enzyme improves efficiency in gene-directed enzyme prodrug therapy.
    Nature biotechnology, 1997, Volume: 15, Issue:13

    Topics: 3T3 Cells; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Drug Delivery Systems; Female; gamma-Glutamyl Hydrolase; Gene Expression Regulation, Enzymologic; Glutamates; Glycosylation; Humans; Membrane Proteins; Methotrexate; Mice; Mice, Nude; Mutation; Neoplasm Transplantation; Nitrogen Mustard Compounds; Prodrugs; Transfection; Tumor Cells, Cultured

1997
Regressions of established breast carcinoma xenografts by carboxypeptidase G2 suicide gene therapy and the prodrug CMDA are due to a bystander effect.
    Human gene therapy, 2000, Jan-20, Volume: 11, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Body Weight; Breast Neoplasms; Female; gamma-Glutamyl Hydrolase; Genetic Therapy; Glutamates; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Nitrogen Mustard Compounds; Prodrugs; Time Factors

2000